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Brown University biochemist targets diabetes

People with type 2 diabetes can make insulin but their bodies use it so poorly that glucose levels run amok. It's been difficult for scientists to understand what's going awry in the way that tiny, fast-moving proteins signal and regulate glucose metabolism. As a result, while drugs can help somewhat, many patients still must monitor their glucose and inject insulin.

10 Jan 2014

Researchers reveal newest weapon to visualize shape and motion of RNA

Qi Zhang sees himself as a warrior. In his lab at the University of North Carolina at Chapel Hill, he wages war on genetic diseases such as cancer and heart disease on a battlefield measured with single atoms.

10 Jan 2014

Biologists discover new pathway for repairing nerve cells

Penn State University molecular biologists have discovered a brand-new pathway for repairing nerve cells that could have implications for faster and improved healing. The researchers describe their findings in a paper titled "Dendrite injury triggers DLK-independent regeneration," which will be published in the 30 January 2014 issue of the journal Cell Reports.

10 Jan 2014

Aetna is helping to reverse abuse of prescription painkillers

Abuse of prescription painkillers, known as opioids, is a widespread and growing problem in the United States. The epidemic adds billions of dollars to health care, work place and criminal justice costs each year.

10 Jan 2014

Researchers discover key step to stem bleeding, reduce obstruction in blood flow during clot formation

Red blood cells are the body's true shape shifters, perhaps the most malleable of all cell types, transforming - among many other forms -- into compressed discs capable of going through capillaries with diameters smaller than the blood cell itself.

10 Jan 2014

Prenatal exposure to maternal stress hormones predicts nicotine dependence for daughters

Tobacco smoking by pregnant women has long been viewed as a public health risk because of smoking's adverse effects on the development of a fetus.

10 Jan 2014

Remission from depression is delayed in adults who experienced physical abuse in childhood

Remission from depression is delayed in adults who have experienced childhood physical abuse or parental addictions, a new study by University of Toronto researchers has found.

10 Jan 2014

Discovery opens new therapeutic avenue for chronic skin condition affecting millions

Researchers from the La Jolla Institute for Allergy and Immunology have revealed a critical player in the cellular interactions leading to eczema - a chronic inflammatory skin condition affecting more than 14 million U.S. children and adults.

10 Jan 2014

T2HemoStat detection of novel clot behavior could direct therapeutic choices for stroke, heart attack victims

T2 Biosystems, a company developing direct detection products enabling superior diagnostics, announced that scientists from the University of Pennsylvania and T2 Biosystems have published a paper in Blood describing novel clot structure biology detected while testing T2 Bio's T2HemoStat-.

10 Jan 2014

New study gives hope for novel glioblastoma multiforme treatment

A new study is giving researchers hope that novel targeted therapies can be developed for glioblastoma multiforme, the most common and most aggressive form of brain cancer, after demonstrating for the first time that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) is a driving force behind the disease's aggressive and invasive nature.

9 Jan 2014

Study questions widely used method of diagnosing acute mountain sickness

A study led by University of British Columbia scientists calls into question a widely used method of diagnosing acute mountain sickness.

9 Jan 2014

Researchers develop personalized tool to predict likelihood of prostate cancer overdiagnosis

Studies have found that prostate cancer is overdiagnosed in up to 42 percent of cases, prompting men to receive unnecessary treatment that can cause devastating side effects, including impotence and incontinence.

9 Jan 2014

Study provides details to help scientists design better vaccines for Plasmodium vivax

A form of malaria common in India, Southeast Asia and South America attacks human red blood cells by clamping down on the cells with a pair of proteins, new research at Washington University School of Medicine in St. Louis has revealed.

9 Jan 2014

TSRI researchers develop new fluid biopsy technique to identify patients at high risk of heart attack

A new "fluid biopsy" technique that could identify patients at high risk of a heart attack by identifying specific cells as markers in the bloodstream has been developed by a group of researchers at The Scripps Research Institute.

9 Jan 2014

Attenuated psychosis syndrome shows clinical significance

The community prevalence of attenuated psychosis syndrome is sufficient to make it a valid addition to the DSM-5, but only with revisions to the current criteria, findings from the BEAR Study show.

9 Jan 2014

Bipolar screening tools not tailored to young people

Current screening tools for bipolar disorder are poorly validated in the age group most at risk for developing the condition, say researchers.

9 Jan 2014

New study compares blood pressure management in the US and England

In the US but not in England, patients on low incomes with high blood pressure have their condition managed poorly compared with those who earn more.

9 Jan 2014

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Biogen Idec and Sangamo BioSciences, Inc. announced today an exclusive worldwide collaboration and license agreement focused on the development of therapeutics for hemoglobinopathies, inherited conditions that result from the abnormal structure or underproduction of hemoglobin.

9 Jan 2014

Nottingham scientists exploit MRI technology to assist in the treatment of IBS

Scientists at The University of Nottingham are leading the world in exploiting MRI technology to assist in the treatment and diagnosis of Irritable Bowel Syndrome, a condition that causes serious inconvenience and discomfort to sufferers.

9 Jan 2014

Zymeworks, ImClone Systems partner to develop novel bi-specific antibody oncology therapeutics

Zymeworks Inc. today announced that it has entered into a licensing and collaboration agreement with ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company, to develop an undisclosed number of novel bi-specific antibody oncology therapeutics using Zymeworks' proprietary Azymetric platform. Bi-specific antibodies have the potential to provide improved outcomes for patients by simultaneously targeting two tumor associated antigens to induce a synergistic therapeutic response.

9 Jan 2014

Medical Research News

Brown University biochemist targets diabetes

Researchers reveal newest weapon to visualize shape and motion of RNA

Biologists discover new pathway for repairing nerve cells

Aetna is helping to reverse abuse of prescription painkillers

Researchers discover key step to stem bleeding, reduce obstruction in blood flow during clot formation

Prenatal exposure to maternal stress hormones predicts nicotine dependence for daughters

Remission from depression is delayed in adults who experienced physical abuse in childhood

Discovery opens new therapeutic avenue for chronic skin condition affecting millions

T2HemoStat detection of novel clot behavior could direct therapeutic choices for stroke, heart attack victims

New study gives hope for novel glioblastoma multiforme treatment

Study questions widely used method of diagnosing acute mountain sickness

Researchers develop personalized tool to predict likelihood of prostate cancer overdiagnosis

Study provides details to help scientists design better vaccines for Plasmodium vivax

TSRI researchers develop new fluid biopsy technique to identify patients at high risk of heart attack

Attenuated psychosis syndrome shows clinical significance

Bipolar screening tools not tailored to young people

New study compares blood pressure management in the US and England

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Nottingham scientists exploit MRI technology to assist in the treatment of IBS

Zymeworks, ImClone Systems partner to develop novel bi-specific antibody oncology therapeutics

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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