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Angioplasty may not provide additional benefits compared to drug therapy for patients with stable CAD

For patients with stable coronary artery disease (CAD) who are not experiencing a heart attack and an abnormal stress test, treatment of their narrowed arteries by the common procedure of angioplasty may not provide additional benefits compared to drug therapy alone.

9 Dec 2013

Scientists identify important new genes for epilepsy

Scientists screening the DNA of large cohorts for known and suspected epilepsy associated genes are finding that, while some genes are implicated in discrete phenotypes or forms of epilepsy, other genes are implicated in a wider range of phenotypes. Although ion channel genes are a common cause of epilepsy, the researchers also report a significant number of epilepsy patients with mutations in non-ion channel genes. The studies have important implications for treatment, prognosis and risk counseling.

9 Dec 2013

Study: Uncontrolled epilepsy associated with higher healthcare utilization

Seizures in people with epilepsy are commonly treated with anti-epileptic drugs (AEDs) but 30-40 percent do not achieve adequate seizure control, predisposing them to severe health risks, impaired quality of life and higher healthcare costs.

9 Dec 2013

Low-income women less likely to receive breast cancer treatment

Women with interruptions in health insurance coverage or with low income levels had a significantly increased likelihood of failing to receive breast cancer care that is in concordance with recommended treatment guidelines, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.

9 Dec 2013

Underlying loss of awareness during partial seizures is same as deep sleep

Epilepsy patients with complex partial seizures have impaired consciousness during seizure episodes and typically have no memory of the event. However, the mechanisms of seizure unconsciousness are unclear.

9 Dec 2013

Researchers find how olfactory receptor variation impacts human odor perception

According to Gertrude Stein, "A rose is a rose is a rose," but new research indicates that might not be the case when it comes to the rose's scent. Researchers from the Monell Center and collaborating institutions have found that as much as 30 percent of the large array of human olfactory receptor differs between any two individuals. This substantial variation is in turn reflected by variability in how each person perceives odors.

9 Dec 2013

Researchers investigate effect of epilepsy surgery on patients lives

Resective surgery is an effective treatment for dug-resistant epilepsy. To investigate the effect of epilepsy surgery on patients lives, researchers from the Comprehensive Epilepsy Program at the Henry Ford Hospital in Detroit conducted a long-term retrospective follow up of surgical patients and correlated post-surgical psychosocial outcomes with seizure outcome and brain area surgically treated.

9 Dec 2013

Study helps explain why survival gap persists for African-Americans with head and neck cancer

A team of scientists at Johns Hopkins and in Texas has identified a handful of genetic mutations in black Americans, in addition to some chemical alterations affecting gene activity, which may help explain why the death rate among African-Americans from the most common form of head and neck cancer continues to hover some 18 percent higher above the death rate of whites with the same cancer.

9 Dec 2013

High frequency cell phone users have lower GPA, higher anxiety, and lower happiness in life

Today, smartphones are central to college students' lives, keeping them constantly connected with friends, family and the Internet. Students' cell phones are rarely out of reach whether the setting is a college classroom, library, recreational center, cafeteria or dorm room.

9 Dec 2013

Increased levels of protein HSET linked with worse breast cancer outcomes in African-Americans

Among African-American women with breast cancer, increased levels of the protein HSET were associated with worse breast cancer outcomes, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.

9 Dec 2013

People lack knowledge about efficacy of HPV vaccine in preventing cervical cancer

Knowledge about the efficacy of the human papillomavirus vaccine in preventing cervical cancer was lacking in the majority of survey respondents for whom the information would be relevant, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.

9 Dec 2013

Researchers find huge diversity in how different organisms age

In our youth we are strong and healthy and then we weaken and die - that's probably how most would describe what ageing is all about. But, in nature, the phenomenon of ageing shows an unexpected diversity of patterns and is altogether rather strange, conclude researchers from The University of Southern Denmark.

9 Dec 2013

UCSF awarded $9.45M federal grant to transform, revolutionize treatment of prostate cancer

UC San Francisco has been awarded a major federal grant to "transform and revolutionize" the treatment of prostate cancer, the second most common form of cancer among American men.

9 Dec 2013

Bonn researchers use reprogrammed neurons for drug testing in Alzheimer patients

Why do certain Alzheimer medications work in animal models but not in clinical trials in humans? A research team from the University of Bonn and the biomedical enterprise LIFE & BRAIN GmbH has been able to show that results of established test methods with animal models and cell lines used up until now can hardly be translated to the processes in the human brain.

9 Dec 2013

Scientists target protein-detection approach to systematically measure human repertoire of proteins

An international team of scientists led by Fred Hutchinson Cancer Research Center cancer proteomics expert Amanda Paulovich, M.D., has demonstrated the feasibility of large-scale, standardized protein measurements, which are necessary for validation of disease biomarkers and drug targets.

9 Dec 2013

Scientists receive 2013 Horwitz Prize for discoveries on how brain calculates location, navigation

Edvard and May-Britt Moser of the Norwegian University of Science and Technology (NTNU), and John O'Keefe, from University College London have been awarded the 2013 Louisa Gross Horwitz Prize for discoveries that have illuminated how the brain calculates location and navigation.

9 Dec 2013

Skin is capable of communicating with liver, say researchers

Researchers from the University of Southern Denmark have discovered that the skin is capable of communicating with the liver. The discovery has surprised the scientists, and they say that it may help our understanding of how skin diseases can affect the rest of the body.

9 Dec 2013

Downregulation of caveolin-1 contributes to synaptic plasticity deficit in hippocampus of aged rats

Caveolin-1 may be a new target for interfering with age-dependent decline in synaptic plasticity. To explore the relationship between synaptic plasticity in the aging process and changes in learning and memory, Dr. Yang Liu and coworkers from the First Affiliated Hospital, Dalian Medical University, China examined synaptophysin expression in the hippocampus, cortex and cerebellum of rats at different ages, and analyzed the association between synaptophysin expression and cognition and behaviors.

9 Dec 2013

Researchers identify mechanism implicated in brain cancer and drug that decreases brain tumor growth

Researchers at the University of Calgary's Hotchkiss Brain Institute (HBI) have made a discovery that could lead to better treatment for patients suffering from brain cancer.

9 Dec 2013

NIH scientists film early concussion damage and describe brain's response to injury

There is more than meets the eye following even a mild traumatic brain injury. While the brain may appear to be intact, new findings reported in Nature suggest that the brain's protective coverings may feel the brunt of the impact.

9 Dec 2013

Medical Research News

Angioplasty may not provide additional benefits compared to drug therapy for patients with stable CAD

Scientists identify important new genes for epilepsy

Study: Uncontrolled epilepsy associated with higher healthcare utilization

Low-income women less likely to receive breast cancer treatment

Underlying loss of awareness during partial seizures is same as deep sleep

Researchers find how olfactory receptor variation impacts human odor perception

Researchers investigate effect of epilepsy surgery on patients lives

Study helps explain why survival gap persists for African-Americans with head and neck cancer

High frequency cell phone users have lower GPA, higher anxiety, and lower happiness in life

Increased levels of protein HSET linked with worse breast cancer outcomes in African-Americans

People lack knowledge about efficacy of HPV vaccine in preventing cervical cancer

Researchers find huge diversity in how different organisms age

UCSF awarded $9.45M federal grant to transform, revolutionize treatment of prostate cancer

Bonn researchers use reprogrammed neurons for drug testing in Alzheimer patients

Scientists target protein-detection approach to systematically measure human repertoire of proteins

Scientists receive 2013 Horwitz Prize for discoveries on how brain calculates location, navigation

Skin is capable of communicating with liver, say researchers

Downregulation of caveolin-1 contributes to synaptic plasticity deficit in hippocampus of aged rats

Researchers identify mechanism implicated in brain cancer and drug that decreases brain tumor growth

NIH scientists film early concussion damage and describe brain's response to injury

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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