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Scientists identify gene encoding hormone to treat heart diseases

Scientists at A*STAR's Institute of Medical Biology (IMB) and Institute of Molecular and Cellular Biology (IMCB) have identified a gene encoding a hormone that could potentially be used as a therapeutic molecule to treat heart diseases.

9 Dec 2013

Study: Ethnic groups with high prevalence of diabetes have high hepatocellular carcinoma rates

Diabetes was associated with an increased risk for developing a type of liver cancer called hepatocellular carcinoma, and this association was highest for Latinos, followed by Hawaiians, African-Americans, and Japanese-Americans, according to results presented here at the Sixth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held Dec. 6-9.

9 Dec 2013

Saudi Human Genome Program to study genetic basis of all disease in the Kingdom

The King Abdulaziz City for Science and Technology, Saudi Arabia's national funding agency, and Life Technologies Corporation today announce The Saudi Human Genome Program – a national research project to study the genetic basis of all disease in the Kingdom and throughout the Middle East and use the findings to offer the ultimate personal care in Saudi Arabia.

8 Dec 2013

Scientists recommend testing for Pearson syndrome in patients with congenital anemia

Some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan Anemia, may actually be affected by a very rare anemia syndrome that has a different disease course and treatment, say scientists from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

8 Dec 2013

Study provides possible therapeutic strategy for Alzheimer's disease via progesterone

Steroid hormones and their metabolites within the central nervous system are commonly defined as neuroactive steroids or neurosteroids. Although neuroactive steroids have been shown to improve learning and memory ability and protect against amyloid beta peptide-induced neurotoxicity, changes in their level during Alzheimer's disease and their role in Aβ-mediated cognitive impairment remain elusive given the limitation in sample sizes and analysis methods.

8 Dec 2013

PKM2 protein controls mitosis, saving cancer cells from death and promoting brain tumor growth

Researchers have caught a protein they previously implicated in a variety of cancer-promoting roles performing a vital function in cell division, survival and development of brain tumors.

8 Dec 2013

Children with higher parental stress gain more weight

Parental stress is linked to weight gain in children, according to a new study from St. Michael's Hospital. The study found that children whose parents have high levels of stress have a Body Mass Index, or BMI, about 2 per cent higher than those whose parents have low levels of stress. Children with higher parental stress also gained weight at a 7 per cent higher rate during the study period than other children.

8 Dec 2013

Researchers may have figured out ways to attack Meniere's disease

Researchers at University of Colorado School of Medicine may have figured out what causes Meniere's disease and how to attack it. According to Carol Foster, MD, from the department of otolaryngology and Robert Breeze, MD, a neurosurgeon, there is a strong association between Meniere's disease and conditions involving temporary low blood flow in the brain such as migraine headaches.

7 Dec 2013

Study explains important link between ED and development of coronary artery disease

Erectile dysfunction is caused by the inability of the artery that supplies blood to the penis to expand and contract properly. The study of this mechanism has led to a new understanding of the important link between ED and the development of coronary artery disease, and to new strategies for prevention and treatment, as described in Journal of Men's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

7 Dec 2013

Novel device may simplify monitoring of patients' response to treatment for ovarian cancer

A microchip-based device developed by Massachusetts General Hospital investigators may greatly simplify the monitoring of patients' response to treatment for ovarian cancer - the most lethal form of gynecologic cancer - and certain other malignancies.

6 Dec 2013

New study reports first evidence of specific molecular changes in the body with meditation

With evidence growing that meditation can have beneficial health effects, scientists have sought to understand how these practices physically affect the body.

6 Dec 2013

NYU Langone Medical Center researchers find link between gut bacteria and colorectal cancer

In one of the largest epidemiological studies of human gut bacteria and colorectal cancer ever conducted, a team of researchers at NYU Langone Medical Center has found a clear association between gut bacteria and colorectal cancer. The study, published today in the Journal of the National Cancer Institute, discovered that colorectal cancer patients had fewer beneficial bacteria and more harmful bacteria than people without the disease.

6 Dec 2013

Kolltan Pharmaceuticals signs license agreement with University of Toronto for novel anti-KIT antibodies

Kolltan Pharmaceuticals, a privately held biopharmaceutical company, today announced the Company has signed a license agreement with the University of Toronto for novel anti-KIT receptor tyrosine kinase antibodies identified in the laboratories of Dr. Sachdev Sidhu at the University of Toronto and the laboratory of Dr. Joseph Schlessinger of Yale University.

6 Dec 2013

Maternal weight issues spell wheezing trouble for children

High maternal weight and gestational weight gain are independently associated with an increased risk for wheezing in preschool age children, a Dutch study has found.

6 Dec 2013

Brain network disruption crosses psychosis diagnostic boundaries

Disruption of cortical information processing occurs in patients with psychosis regardless of whether they have a psychotic or affective diagnosis, research shows.

6 Dec 2013

Inflexible thinking in ADHD blamed on bipolar disorder

Impaired cognitive flexibility in patients with attention deficit hyperactivity disorder (ADHD) may be entirely due to the presence of comorbid bipolar disorder, say researchers.

6 Dec 2013

ALS TDI forms research partnership with Neurimmune to advance potential treatments for ALS

The ALS Therapy Development Institute (ALS TDI), together with its wholly-owned subsidiary, Anelixis Therapeutics, announced today that it has formed a research partnership with Neurimmune to advance potential treatments for ALS, also known as Lou Gehrig's disease.

6 Dec 2013

New research finds that H7N9 still mainly adapted for infecting birds, not humans

Avian influenza virus H7N9, which killed several dozen people in China earlier this year, has not yet acquired the changes needed to infect humans easily, according to a new study by scientists at The Scripps Research Institute. In contrast to some initial studies that had suggested that H7N9 poses an imminent risk of a global pandemic, the new research found, based on analyses of virus samples from the Chinese outbreak, that H7N9 is still mainly adapted for infecting birds, not humans.

6 Dec 2013

Researchers illuminate inner workings of enzymes placed inside the outer envelopes of cells

For what is believed to be the first time, researchers at The Johns Hopkins University have illuminated the inner workings of an important class of enzymes located inside the outer envelopes of cells. Much to their surprise, they report, these protein cutters, called rhomboid proteases, are entirely different than nearly every other type of enzyme studied, showing no attraction to the proteins they cut and being extremely slow in making their cuts.

6 Dec 2013

Study uncovers novel mechanism by which glioblastoma evades targeted therapies

A Ludwig Cancer Research study has uncovered an entirely novel mechanism by which glioblastoma, the most common kind of brain cancer, evades targeted therapies. Published in the current issue of the journal Science, the paper describes how GBM tumor cells essentially hide the signaling molecule targeted by such therapies, adding a layer of complexity to current models of drug resistance in cancer.

6 Dec 2013

Medical Research News

Scientists identify gene encoding hormone to treat heart diseases

Study: Ethnic groups with high prevalence of diabetes have high hepatocellular carcinoma rates

Saudi Human Genome Program to study genetic basis of all disease in the Kingdom

Scientists recommend testing for Pearson syndrome in patients with congenital anemia

Study provides possible therapeutic strategy for Alzheimer's disease via progesterone

PKM2 protein controls mitosis, saving cancer cells from death and promoting brain tumor growth

Children with higher parental stress gain more weight

Researchers may have figured out ways to attack Meniere's disease

Study explains important link between ED and development of coronary artery disease

Novel device may simplify monitoring of patients' response to treatment for ovarian cancer

New study reports first evidence of specific molecular changes in the body with meditation

NYU Langone Medical Center researchers find link between gut bacteria and colorectal cancer

Kolltan Pharmaceuticals signs license agreement with University of Toronto for novel anti-KIT antibodies

Maternal weight issues spell wheezing trouble for children

Brain network disruption crosses psychosis diagnostic boundaries

Inflexible thinking in ADHD blamed on bipolar disorder

ALS TDI forms research partnership with Neurimmune to advance potential treatments for ALS

New research finds that H7N9 still mainly adapted for infecting birds, not humans

Researchers illuminate inner workings of enzymes placed inside the outer envelopes of cells

Study uncovers novel mechanism by which glioblastoma evades targeted therapies

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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