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Scientists discover new drug mechanism to reduce risk of infections

Scientists at A*STAR's Singapore Immunology Network (SIgN) have discovered the exact mode of action by plerixafor, a drug commonly prescribed to stimulate immune responses in patients suffering from neutropenia, which causes them to become prone to oral, skin, genital infections and in worst cases, a fatal whole-body infection.

15 Nov 2013

Study finds consistent sleep pattern can reduce risk of illness among adolescents

Newly released findings from Bradley Hospital published in the Journal of Sleep Research have found that acute illnesses, such as colds, flu, and gastroenteritis were more common among healthy adolescents who got less sleep at night. Additionally, the regularity of teens' sleep schedules was found to impact their health.

15 Nov 2013

Copper intake via food and water can accelerate growth of tumors

Copper imbalances have been associated with a number of pathological conditions, including cancer. Publishing in PNAS scientists at EPFL have found that copper in drinking water - given at the maximum levels permitted in public water supplies - accelerated the growth of tumors in mice. On the other hand, reducing copper levels reduced tumor growth.

15 Nov 2013

Lower doses of antimalarial drug effective in reducing malaria transmission

Lower doses of the antimalarial drug primaquine are as effective as higher doses in reducing malaria transmission, according to a study published today in Lancet Infectious Diseases by London School of Hygiene & Tropical Medicine researchers.

15 Nov 2013

Study finds link between alcohol consumption and reduced condom use among college women

A new study from researchers at The Miriam Hospital finds a link between alcohol consumption and reduced condom use among college women. The findings also indicate that women who smoke marijuana with established romantic partners may use condoms less often.

15 Nov 2013

$Research may explain why people who take bone-strengthening drugs are at-risk for atypical fractures$

Research may explain why people who take bone-strengthening drugs are at-risk for atypical fractures

Research with baboons at the Texas Biomedical Research Institute may help explain why some people who take bone-strengthening drugs like bisphosphonates are at-risk for atypical fractures in the long bones in their legs.

15 Nov 2013

Researchers create new statistical tools to find clues about cancer from raw data

Researchers at Rice University, Baylor College of Medicine (BCM) and the University of Texas at Austin are working together to create new statistical tools that can find clues about cancer that are hidden like needles in enormous haystacks of raw data.

15 Nov 2013

Researchers exploit power of evolution to create new drug for use against heart disease

An international team of researchers led by the University of Leicester has "harnessed the power of evolution" to create a new drug for possible use against heart disease, inflammation and other illnesses.

15 Nov 2013

Few newly diagnosed high-cholesterol patients get screened for thyroid dysfunction: Study

Despite current guidelines that recommend newly diagnosed high-cholesterol patients have a TSH blood test done to make sure they do not have hypothyroidism, researchers from Boston University School of Medicine and Boston Medical Center have found that only about half of these patients were screened for thyroid dysfunction.

15 Nov 2013

Small molecule compound shows significant success in controlling polyomaviruses

A team of scientists reports that a small molecule compound showed significant success in controlling the infectivity and spread of three polyomaviruses in human cell cultures. To date there has been no medicine approved to treat such viruses, which prey on transplant recipients, people with HIV, and others whose immune systems have been weakened.

15 Nov 2013

Eating protein-rich breakfast improves appetite control throughout the morning

While Americans generally consume enough protein, they tend to eat a small amount at breakfast, moderate amounts at lunch, and the largest amount at dinner. New research presented today at The Obesity Society's annual scientific meeting in Atlanta shows that eating high protein sausage and egg-based breakfasts curbed hunger throughout the morning, compared with a low-protein breakfast (pancakes and syrup) or skipping breakfast, in 18-55-year-old women.

15 Nov 2013

Identifying 'sensome' of microglia could improve treatments for neurodegenerative disorders

Massachusetts General Hospital investigators have used a new sequencing method to identify a group of genes used by the brain's immune cells - called microglia - to sense pathogenic organisms, toxins or damaged cells that require their response.

15 Nov 2013

Medical researchers discover structure of potential drug target for rare genetic disease

Medical researchers at the University of Alberta have discovered the structure of a potential drug target for a rare genetic disease, paving the way for an alternative treatment for the condition.

15 Nov 2013

Annexin A5 protein may have therapeutic potential for treatment of sepsis

Sepsis is the leading cause of in-hospital death and there is no specific treatment for it. Now, research led by Dr. Qingping Feng of Western University (London, Canada) suggests a protein called recombinant human annexin A5 may have therapeutic potential for the treatment of this disease. The paper is published in advance, online in Critical Care Medicine.

15 Nov 2013

When schools adopt healthful nutrition policies and practices, kids' diets improve

When schools adopt healthful nutrition policies and practices, kids' diets improve. According to new research led by Michigan State University and published in the current issue of Childhood Obesity, when schools offered snacks in lunchtime a la carte or vending that were mostly or entirely healthful, students responded with improvements in their diets, said Katherine Alaimo, MSU associate professor of food, science and human nutrition.

15 Nov 2013

Spirituality in teens linked with increased positive social behaviors, reduced narcissism

If the spirit is truly willing, perhaps the flesh is not so weak, after all. Increased spirituality in teens undergoing substance abuse treatment is associated with greater likelihood of abstinence (as measured by toxicology screens), increased positive social behaviors, and reduced narcissism, according to a study by researchers from The University of Akron, Case Western Reserve University (CWRU) and Baylor University.

15 Nov 2013

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Signum Dermalogix, Inc. announced that the National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the company a Small Business Innovation Research Phase II grant totaling $1.6 million for the development of a topical drug candidate for atopic dermatitis.

15 Nov 2013

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Global Genomics Group and Metabolon today announced that they have entered into a collaboration agreement to investigate biological networks and pathways in order to discover novel biomarkers and pharmaceutical targets for cardiovascular diseases.

15 Nov 2013

Findings provide insights into the factors that affect surgeons’ reactions to major surgical complications

Many surgeons are seriously affected on an emotional level by major surgical complications, and they often feel that institutional support is inadequate. Those are among the conclusions of a small study published recently in the BJS (British Journal of Surgery).

14 Nov 2013

LLN spirometry inadequate to detect airflow obstruction

Research published in Thorax indicates that use of a lower limit of normal spirometric threshold fails to identify a number of patients with airflow obstruction and chronic obstructive pulmonary disease.

14 Nov 2013

Medical Research News

Scientists discover new drug mechanism to reduce risk of infections

Study finds consistent sleep pattern can reduce risk of illness among adolescents

Copper intake via food and water can accelerate growth of tumors

Lower doses of antimalarial drug effective in reducing malaria transmission

Study finds link between alcohol consumption and reduced condom use among college women

Research may explain why people who take bone-strengthening drugs are at-risk for atypical fractures

Researchers create new statistical tools to find clues about cancer from raw data

Researchers exploit power of evolution to create new drug for use against heart disease

Few newly diagnosed high-cholesterol patients get screened for thyroid dysfunction: Study

Small molecule compound shows significant success in controlling polyomaviruses

Eating protein-rich breakfast improves appetite control throughout the morning

Identifying 'sensome' of microglia could improve treatments for neurodegenerative disorders

Medical researchers discover structure of potential drug target for rare genetic disease

Annexin A5 protein may have therapeutic potential for treatment of sepsis

When schools adopt healthful nutrition policies and practices, kids' diets improve

Spirituality in teens linked with increased positive social behaviors, reduced narcissism

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Findings provide insights into the factors that affect surgeons’ reactions to major surgical complications

LLN spirometry inadequate to detect airflow obstruction

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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