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Study: Music therapy improves self-esteem, reduces depression in children

Researchers at Queen's University Belfast have discovered that music therapy reduces depression in children and adolescents with behavioural and emotional problems.

23 Oct 2014

Novel approach may help detect invasive aspergillosis

Many different microbes can cause pneumonia, and treatment may be delayed or off target if doctors cannot tell which bug is the culprit. A novel approach—analyzing a patient's breath for key chemical compounds made by the infecting microbe—may help detect invasive aspergillosis, a fungal infection that is a leading cause of mortality in patients with compromised immune systems, according to a proof-of-concept study now online in Clinical Infectious Diseases.

23 Oct 2014

Scientists use innovative exome sequencing strategy to identify new gene associated with ALS

Using an innovative exome sequencing strategy, a team of international scientists led by John Landers, PhD, at the University of Massachusetts Medical School has shown that TUBA4A, the gene encoding the Tubulin Alpha 4A protein, is associated with familial amyotrophic lateral sclerosis (ALS), a fatal neurological disorder also known as Lou Gehrig's Disease.

23 Oct 2014

ADI develops ELISA test kits for detection of Ebola viral protein antibodies

San Antonio, Texas-based Biotech Company Alpha Diagnostic Int'l has developed and released several convenient, rapid, and sensitive ELISA test kits for the detection of major Ebola viral protein antibodies (Glycoprotein, GP; Nucleoprotein, NP, and Viral Protein 40 or VP40).

23 Oct 2014

Afatinib active against NSCLC nervous system metastases

Heavily pretreated patients with epidermal growth factor receptor-mutated non-small-cell lung cancer and central nervous system metastases may benefit from treatment with afatinib, say German researchers.

22 Oct 2014

Six platinum cycles no better than four for advanced NSCLC

Six cycles of adjuvant platinum-based chemotherapy is no better than three or four cycles for patients with advanced non-small-cell lung cancer, meta-analysis results suggests.

22 Oct 2014

Genetics underpin bullying victimisation influence on paranoia

Bullying victimisation in childhood may indicate genetic risk for later psychosis, rather than being an environmental trigger, say UK researchers.

22 Oct 2014

$Insulin resistance linked to treatment-refractory bipolar disorder$

Insulin resistance linked to treatment-refractory bipolar disorder

Patients with bipolar disorder who are insulin resistant are likely to also be refractory to mood-stabilising treatment, report researchers.

22 Oct 2014

Vascular receptor autoantibodies implicated in SSc-PAH

medwireNews: Autoantibodies to endothelin receptor type A and angiotensin receptor type-1 predict the development of, and mortality from, systemic sclerosis-associated pulmonary arterial hypertension, research suggests.

22 Oct 2014

HRQoL goals may improve outcome in PAH

Health-related quality of life before and during treatment for pulmonary arterial hypertension is significantly associated with survival, Brazilian researchers report.

22 Oct 2014

Changing placebo response dilutes antipsychotic trial power

Factors including patients’ expectations may underlie an increased placebo response in antipsychotic randomised controlled trials published since 1960, say researchers.

22 Oct 2014

Verbal abuse worsens bipolar disease outcome

Experiencing verbal abuse in childhood has a lasting negative effect on the course of bipolar disorder, researchers have found.

22 Oct 2014

‘Neuroprotective’ effects of smoking disputed

The apparent neuroprotective effect of smoking may simply be because ease of quitting smoking is a marker of prodromal Parkinson’s disease, say researchers.

22 Oct 2014

Levodopa dose linked to malnutrition risk in Parkinson’s disease

The malnutrition often seen in patients with Parkinson’s disease could be partly an effect of levodopa medication, research suggests.

22 Oct 2014

Nonmotor predictors of Parkinson’s dementia revealed

Researchers have identified nonmotor and nondopaminergic motor features that predict incident dementia in patients with Parkinson’s disease.

22 Oct 2014

Study identifies new signaling pathway that leads to inflammatory bone erosion in RA patients

A new study by researchers at Hospital for Special Surgery identifies a new signaling pathway that contributes to the development and progression of inflammatory bone erosion, which occurs in patients with rheumatoid arthritis (RA). Rheumatoid arthritis is a systemic inflammatory autoimmune disease that affects millions of adults worldwide.

22 Oct 2014