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Scientists reveal inside story of European regulatory review and approval of Glybera

The scientists who led the team that developed Glybera, the first gene therapy drug approved for use in the Western world, provide a fascinating first-person account of their pioneering work in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

16 May 2013

UHCMC researchers to present data on patient and physician barriers to clinical trials

Researchers from University Hospitals Case Medical Center's Seidman Cancer Center will present findings from two studies evaluating new technologies designed to address common barriers to patient enrollment in clinical trials.

16 May 2013

People suffering from PTSD have risk of developing type 2 diabetes

The presence of posttraumatic stress disorder is significantly associated with the development of type 2 diabetes. This is the finding of scientists from the Helmholtz Zentrum München and the University Hospital Gieβen and Marburg who worked with data from the population-based KORA cohort study.

16 May 2013

Stanford engineers develop new type of nanoscavenger for water purification

Among its many talents, silver is an antibiotic. Titanium dioxide is known to glom on to certain heavy metals and pollutants. Yet other materials do the same for salt. In recent years, environmental engineers have sought to disinfect, depollute, and desalinate contaminated water using nanoscale particles of these active materials. Engineers call them nanoscavengers. The hitch from a technical standpoint is that it is nearly impossible to reclaim the nanoscavengers once in the water.

16 May 2013

Study suggests need for better anti-rejection therapies

Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in the Journal of Clinical Investigation.

16 May 2013

Study finds broader set of concerns for improving quality of life

The majority of cancer doctors, patients, and members of the general public support cutting health care costs by refusing to pay for drugs that don't improve survival or quality of life, according to results of a new study that will be presented by researchers from the Perelman School of Medicine at the University of Pennsylvania during the annual meeting of the American Society of Clinical Oncology in Chicago in early June (Abstract #6518).

16 May 2013

Hydrogel scaffolds can help evaluate how engineering nanoparticles interact with cells

A class of water-loving, jelly-like materials with uses ranges ranging from the mundane, such as superabsorbent diaper liners, to the sophisticated, such as soft contact lenses, could be tapped for a new line of serious work: testing the biological effects of nanoparticles now being eyed for a large variety of uses.

16 May 2013

Journal supplement explores state of nutrition science on white vegetables

Potatoes and other white vegetables are just as important to a healthy diet as their colorful cousins in the produce aisle, according to the authors of a scientific supplement published yesterday in the peer-reviewed journal, Advances in Nutrition.

16 May 2013

Antibiotic stewardship program using MALDI Biotyper reduces hospital stays, overall costs

A co-author of a groundbreaking study documenting reductions in patient length of stay and overall costs from implementation of an antibiotic stewardship program using Bruker's MALDI Biotyper will share her observations at a Bruker symposium to be held during the upcoming American Society for Microbiology General Meeting.

16 May 2013

Mayo Clinic researchers complete world's first whole exome sequence of small intestine carcinoids

Researchers at Mayo Clinic have completed the world's first whole exome sequence of small intestine neuroendocrine tumors, also known to patients and physicians as carcinoids, the most common cancer of the small bowel and one that responds poorly to chemotherapy.

16 May 2013

Researchers explain why cost of care higher for men with severe psoriasis

Men often suffer from more severe cases of psoriasis than women, which may explain why the cost of care for men is higher. This is the conclusion of researchers at Umeå University in a new study.

16 May 2013

Researchers see potential in deploying Akkermansia bacteria to understand and treat obesity

A dominant and useful bacterium called Akkermansia muciniphila is present in the intestinal system of all humans, from babies to the elderly. This microorganism is found in the intestinal mucus layer that protects against intruders.

16 May 2013

Study underscores new paradigm in cancer therapy

In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers.

16 May 2013

$Study: Long-term mortality in patients with refractory angina is surprisingly low$

Study: Long-term mortality in patients with refractory angina is surprisingly low

Death rates associated with patients with refractory angina, or chronic chest pain, are lower than previously considered; therefore, physicians should focus on relieving the chest pain symptoms and improving the quality of life in these patients according to an article published online this week in the European Heart Journal.

16 May 2013

Breathing motor vehicle emissions triggers change in HDL cholesterol

Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries.

16 May 2013

Study reveals how and why developmental genes often take inputs from 2 independent sources

Albert Erives, associate professor in the University of Iowa Department of Biology, and his graduate student, Justin Crocker, currently a postdoctoral researcher at the Howard Hughes Medical Institute Janelia Farm Research Campus, have conducted a study that reveals important and useful insights into how and why developmental genes often take inputs from two independent "morphogen concentration gradients."

16 May 2013

Women in 40s continue to undergo routine breast cancer screenings despite new recommendations

Women in their 40s continue to undergo routine breast cancer screenings despite national guidelines recommending otherwise, according to new Johns Hopkins research.

16 May 2013

Melbourne scientists' discovery may pave way for developing antimalarial drugs

Melbourne scientists have made the surprise discovery that malaria parasites can 'talk' to each other - a social behaviour to ensure the parasite's survival and improve its chances of being transmitted to other humans.

16 May 2013

Researchers show a model of how cells' regulatory systems work

How cells regulate their own function by "accelerating and braking" is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy.

16 May 2013

Finding targets prostate patients who would not benefit from cancer-detecting biopsy

UC Irvine Health urologists and health policy experts report in a new study that two written assessments that identify existing comorbidities - the patient-reported Total Illness Burden Index for Prostate Cancer (TIBI-Cap) and the physician-reported Charlson Comorbidity Index - can successfully target prostate patients who would not benefit from biopsy to discover possible cancer.

16 May 2013

Medical Research News

Scientists reveal inside story of European regulatory review and approval of Glybera

UHCMC researchers to present data on patient and physician barriers to clinical trials

People suffering from PTSD have risk of developing type 2 diabetes

Stanford engineers develop new type of nanoscavenger for water purification

Study suggests need for better anti-rejection therapies

Study finds broader set of concerns for improving quality of life

Hydrogel scaffolds can help evaluate how engineering nanoparticles interact with cells

Journal supplement explores state of nutrition science on white vegetables

Antibiotic stewardship program using MALDI Biotyper reduces hospital stays, overall costs

Mayo Clinic researchers complete world's first whole exome sequence of small intestine carcinoids

Researchers explain why cost of care higher for men with severe psoriasis

Researchers see potential in deploying Akkermansia bacteria to understand and treat obesity

Study underscores new paradigm in cancer therapy

Study: Long-term mortality in patients with refractory angina is surprisingly low

Breathing motor vehicle emissions triggers change in HDL cholesterol

Study reveals how and why developmental genes often take inputs from 2 independent sources

Women in 40s continue to undergo routine breast cancer screenings despite new recommendations

Melbourne scientists' discovery may pave way for developing antimalarial drugs

Researchers show a model of how cells' regulatory systems work

Finding targets prostate patients who would not benefit from cancer-detecting biopsy

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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