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Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterine growth restriction

Increased brain cell apoptosis in intrauterine growth-restricted fetal rats is a key reason for unfavorable long-term prognosis of the nervous system. The harmful effects of intrauterine growth restriction on fetal brain development originate in the womb.

6 Sep 2013

Scientists reveal structure of protein essential for triggering necroptosis

Scientists in Melbourne, Australia, have revealed the structure of a protein that is essential for triggering a form of programmed cell death called necroptosis, making possible the development of new drugs to treat chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis.

6 Sep 2013

Apoptosis can reactivate latent herpesviruses in dying cell

Researchers have found that apoptosis, a natural process of programmed cell death, can reactivate latent herpesviruses in the dying cell. The results of their research, which could have broad clinical significance since many cancer chemotherapies cause apoptosis, was published ahead of print in the Journal of Virology.

6 Sep 2013

Researchers use educational TV characters to promote healthy eating among preschoolers

Researchers at the Hood Center for Children and Families at the Geisel School of Medicine at Dartmouth have received a two-year, $275,000 grant from the National Institutes of Health to develop and test a program that uses children's educational TV characters to promote healthy eating and physical activity among preschoolers.

6 Sep 2013

Self-propagating aggregates key to Alzheimer's, other diseases

Two leading neurology researchers have proposed a theory that could unify scientists' thinking about several neurodegenerative diseases and suggest therapeutic strategies to combat them.

6 Sep 2013

Inner-ear dysfunction can increase hyperactivity, say researchers

Behavioral abnormalities are traditionally thought to originate in the brain. But a new study by researchers at Albert Einstein College of Medicine of Yeshiva University has found that inner-ear dysfunction can directly cause neurological changes that increase hyperactivity.

6 Sep 2013

Study confirms low rates of employment for young autistic adults

A study published in the September 2013 issue of the Journal of the American Academy of Child and Adolescent Psychiatry found that young adults with an autism spectrum disorder have more difficulty transitioning into employment than their peers with different disabilities.

6 Sep 2013

Osteoporosis drug could provide effective pain relief to patients with osteoarthritis

St George's, University of London research has found that a drug normally given to osteoporosis sufferers could provide effective pain relief to patients with knee and hip osteoarthritis.

6 Sep 2013

Behavior problems in childhood may lead to inflammatory conditions later in life

Children with behavioral problems may be at risk of many chronic diseases in adulthood including heart disease, obesity, diabetes, as well as inflammatory illnesses (conditions which are caused by cell damage).

6 Sep 2013

UCLA researchers explain Post-Diverticulitis Irritable Bowel Syndrome

UCLA researchers have described a new form of irritable bowel syndrome that occurs after an acute bout of diverticulitis, a finding that may help lead to better management of symptoms and relief for patients.

6 Sep 2013

CT screening proven effective for lung cancer

There is strong evidence to support the effectiveness of screening for lung cancer with low-dose computed tomography, a systematic review has found.

5 Sep 2013

Asthma exacerbates PE risk

Data from Taiwan show that asthma is associated with a significant increase in the risk for pulmonary embolism, particularly in patients who experience exacerbations.

5 Sep 2013

Negative symptom clue to smoking in schizophrenia patients

Patients with schizophrenia may have a preponderance to cigarette smoking because it reduces negative symptom severity, researchers report.

5 Sep 2013

Acute manic episodes linked to increased edema risk

Bipolar disorder patients admitted to hospital with a manic episode are at an increased risk for lower limb edema, compared with their peers with depressive or non-affective psychosis episodes, study findings show.

5 Sep 2013

Chemotherapy best second-line option for EGFR wild-type NSCLC

Chemotherapy is more effective than erlotinib as second-line therapy in people with advanced non-small-cell lung cancer and wild-type epidermal growth factor receptor genotype, a randomized controlled trial has found.

5 Sep 2013

Study: Death risk is greatest for those who developed hypertrophic cardiomyopathy in childhood

A long-term study of children with a complex heart condition called hypertrophic cardiomyopathy (HCM) found that the risk of death or need for immediate listing for heart transplantation was greatest for those who developed this disease as infants with congestive heart failure and for children who also had selective inborn errors of metabolism, a group of rare genetic disorders in which one or more of the body's key metabolic processes are disrupted.

5 Sep 2013

Processing of sound in brain is more advanced than previously thought

The processing of sound in the brain is more advanced than previously thought. When we hear a tone, our brain temporarily strengthens that tone but also any tones separated from it by one or more octaves. A research team from Utrecht and Nijmegen published an article on the subject in the journal PNAS on 2 September.

5 Sep 2013

Experimental agent fails to increase HDL levels, reveals new study

The search continues for an agent that increases high-density lipoprotein (HDL) and reduces arterial plaque, after the experimental apolipoprotein A1 (apoA1) inducer, RVX-208 failed to do so in the ApoA1 Synthesis Stimulation and Intravascular Ultrasound for Coronary Atheroma Regression Evaluation (ASSURE) study.

5 Sep 2013

Anti-thrombotic therapy interruption has no influence on perioperative complications in cardiac patients

A shortened pre-surgical interruption of anti-thrombotic therapy, compared to the more traditional one-week interruption, has no influence on perioperative complications in cardiac patients, according to the results of the PRAGUE 14 trial.

5 Sep 2013

Hokusai-VTE findings provide fresh insight into patients with pulmonary embolism

In the treatment of venous thromboembolism (VTE), the oral anticoagulant edoxaban resulted in equal efficacy and better safety compared to standard warfarin when either drug was used with initial low molecular weight heparin (LMWH), according to the results of the Hokusai-VTE trial.

5 Sep 2013