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Optimal lung cancer screening nodule size questioned

Researchers challenge the definition of a positive result in first-round lung cancer screening with low-dose computed tomography in the Annals of Internal Medicine.

19 Feb 2013

Severe childhood asthma blood test hopes dashed

Blood eosinophil counts do not reliably reflect airway eosinophil concentrations in children with severe, therapy-resistant asthma, and therefore cannot be used to make therapeutic decisions, researchers report.

19 Feb 2013

Temper outbursts linked to depression in OCD children

Temper outbursts are common in children with obsessive-compulsive disorder and are associated with depression symptoms, UK researchers report.

19 Feb 2013

Oblique split graft technique avoids rhinoplasty warp

A novel graft technique may reduce the risk of costal cartilage graft warping in patients undergoing septorhinoplasty for saddle nose deformity with depleted source, Turkish surgeons say.

19 Feb 2013

Piroxicam ultrasound combination optimal for knee osteoarthritis

Phonophoresis of the non steroidal anti-inflammatory drug piroxicam with ultrasound is more effective than ultrasound alone for improving pain and other symptoms of mild-to-moderate knee osteoarthritis, show study findings.

19 Feb 2013

Further hearing screens may be required for infants

Some infants go on to develop sensorineural hearing loss despite having passed the universal newborn hearing screen, show study findings.

19 Feb 2013

Oxidative stress: the price of sucrose pain relief in neonates

Although sucrose significantly reduces the pain experienced by preterm neonates undergoing heel lance, it is associated with significant increases in adenosine triphosphate use and oxidative stress, the results of a US study indicate.

19 Feb 2013

Income inequality equals more hospital readmissions

Patients living in areas of uneven wealth-distribution are at an increased risk for hospital readmission, according to US research findings published in the BMJ.

19 Feb 2013

Risk factors for invasive candidiasis in infants clarified

A combination of exposure to broad-spectrum antibiotics and having a platelet count below 50,000/mm3 significantly increases a low-to-normal–weight infant’s chance for developing invasive candidiasis, report researchers.

19 Feb 2013

Clonal evolution explains unpredictable leukemia disease course

Scientists have revealed the complicated clonal evolution of chronic lymphocytic leukemia, giving insight into the variation in disease course and its response to treatment.

19 Feb 2013

High calcium intake raises all cause, CVD mortality risk for women

Latest research examining the potential hazards of a high calcium intake finds an increased mortality risk among women with a high intake through diet and supplements.

19 Feb 2013

Antimuscarinic effective for overactive bladder in elderly

The antimuscarinic drug fesoterodine seems to be an effective and well-tolerated treatment for elderly individuals with an overactive bladder, including those older than 75 years, show findings from a clinical trial.

19 Feb 2013

Depression links PTSD to life quality in bipolar disorder

The association between post-traumatic stress disorder and mental health-related quality of life among individuals with bipolar disorder may be mediated by depressive symptoms, the results of a US study indicate.

19 Feb 2013

First-episode psychosis hits men hard

Men with first-episode psychosis have more severe symptoms than women and are less likely to achieve recovery, say Danish researchers.

19 Feb 2013

Fibromyalgia prevalence is 2.1% of the general population in Germany

Researchers have determined that fibromyalgia prevalence is 2.1% of the general population in Germany. Results appearing in Arthritis Care & Research, a journal published by Wiley on behalf of the American College of Rheumatology (ACR), suggest that fibromyalgia is a spectrum disorder rather than a categorical illness. Additionally, a number of fibromyalgia cases in the general population satisfy proposed criteria for physical symptom disorder—the presence of one or more physical symptoms that impair function, which cannot be explained by another clinical or psychiatric illness.

19 Feb 2013