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Cadherin-catenin-actin structure exerts force inside and between cells in living tissues

If you place certain types of living cells on a microscope slide, the cells will inch across the glass, find their neighbors, and assemble themselves into a simple, if primitive tissue. A new study at Stanford University may help explain this phenomenon, and then some, about the mechanical structure and behavior of complex living organisms.

17 Jul 2012

Better diet before pregnancy lowers GDM risk

Adhering to a healthy diet before pregnancy can significantly reduce a woman’s likelihood for developing gestational diabetes mellitus, show study findings published in the American Journal of Clinical Nutrition.

16 Jul 2012

Once-daily single-tablet HIV therapy developed

A single tablet containing four antiviral agents may be an effective initial once-daily therapy for adults infected with HIV, shows phase III clinical research.

16 Jul 2012

Rheumatoid arthritis patients take-up cancer screening

Insurance records for rheumatoid arthritis patients in the USA indicate that patients are receiving their recommended cervical, breast, and colon cancer screening tests.

16 Jul 2012

Athletes return to elite sport after hip reconstruction

Around three-quarters of elite athletes who undergo arthroscopic labral reconstruction of the hip successfully return to their sport at the same level of competition they were at prior to surgery, a review shows.

16 Jul 2012

Research reveals how metformin reduces HCC risk

For every year that a patient with diabetes takes metformin, their risk for hepatocellular carcinoma reduces, say the authors of a study that also sheds light on the cellular pathway it uses.

16 Jul 2012

Premature babies need to be born in high-level units

The survival benefit of delivering at a high-level neonatal intensive care unit is larger than previously thought, a study shows.

16 Jul 2012

Hemorrhoids may cause erectile dysfunction

Men may be more likely to suffer from erectile dysfunction if they have previously been diagnosed with hemorrhoids, particularly if they are aged under 40 years, report researchers.

16 Jul 2012

Femoroacetabular hip impingement behind sports hernia

A large proportion of athletes with sports hernias also have femoroacetabular impingement of the hip on the same side of the body, results of a magnetic resonance imaging study show.

16 Jul 2012

Treatment deteriorates giant cell arteritis imaging sensitivity

Patients with suspected giant cell arteritis should undergo imaging before or as soon as possible after treatment has started to minimize the chance of a false–negative result, advise German researchers.

16 Jul 2012

Prostate cancer treatment regrets linked to comorbidity

Men with cardiovascular disease are significantly more likely to regret their prostate cancer treatment choice than men without this comorbidity and have an increased risk for adverse effects, US researchers warn.

16 Jul 2012

Smartphone policies would ease distraction during rounds

US attendings would like formal policies governing smartphone use during rounds, show the results of a survey that highlight the potential for smartphones to cause distraction, as well as being useful in this setting.

16 Jul 2012

Physician-targeted intervention could reduce depression in elderly

Older patients whose physicians take part in a practice audit and education-based intervention have reduced odds of depression and self-harm at 24 months – significantly so in the case of self-harm, show results of an Australian trial.

16 Jul 2012

Chest X-ray prevents excess antibiotic use in childhood pneumonia

Use of a chest X-ray as well as traditional clinical parameters to diagnose childhood pneumonia can prevent overdiagnosis and unnecessary use of antibiotics, say researchers.

16 Jul 2012

High cost of ‘weekend effect’ in stroke care

Weekend admission adversely affects a range of quality and safety indicators of acute stroke care, report UK researchers.

16 Jul 2012

Mitochondrial gene regulators involved in Huntington’s disease pathology

Researchers have identified two molecules involved in mitochondrial function that appear to be important in the pathogenesis of Huntington’s disease.

16 Jul 2012

ACE inhibitors ‘protect against pneumonia’

Angiotensin-converting enzyme inhibitors, but not angiotensin receptor blockers, reduce the risk of pneumonia, findings from a meta-analysis show.

16 Jul 2012

Osteoporosis and sarcopenia: researchers at UMKC receive $8.3 million to study relationship

The University of Missouri-Kansas City has received a five-year, $8.3 million grant from the National Institute on Aging, part of the National Institutes of Health, to study the relationship between osteoporosis (loss of bone density) and sarcopenia (loss of muscle mass) as people age.

16 Jul 2012

DMAA stimulant does not originate from natural substances

A new study published in the journal Drug Testing and Analysis found that DMAA, a stimulant often found in many nutritional and sports supplements, does not originate from natural substances and is actually comprised of synthetic compounds.

14 Jul 2012

Chica and Heinz Schaller Foundation supports work of five new C.H.S. research groups

Five new research groups for young scientists, the C.H.S. research groups, have taken up their work in basic biomedical research. To mark the occasion, the German Cancer Research Center (DKFZ) will hold a ceremony on 20 July 2012.

14 Jul 2012