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Identification of IL-9 antitumor activity in melanoma

High expression of interleukin -9 in immune cells inhibits growth of melanoma, show study findings suggesting a role for this T-cell cytokine in tumor suppression.

13 Jul 2012

Treatment-resistant insomnia exacerbates major depression

Reports from a case series study indicate that patients with major depression have high rates of treatment-resistant, residual insomnia, and that insomnia during the early remission phase could lead to recurrence of depressive episodes.

13 Jul 2012

Key risk features predictive for suicide in bipolar disorder identified

Study findings suggest that patients with bipolar disorder who present with mixed-states, melancholic depressive features, or have multiple antidepressant treatment episodes are at increased risk for suicide.

13 Jul 2012

Adding functional skills training to CRT improves schizophrenia functioning

Adding functional skills training to cognitive remediation therapy significantly improves functional competence and real-world behavior in patients with schizophrenia, show study findings.

13 Jul 2012

Cranberry benefits not an old wives’ tale

Consuming cranberry products can reduce the risk for urinary tract infections, particularly in women, a meta-analysis shows.

13 Jul 2012

Incident HF an ‘extreme high-risk’ condition

Patients have a markedly increased risk for stroke and death in the month following a new heart failure diagnosis, say researchers.

13 Jul 2012

Femoral Acetabular Impingement may contribute to groin pain in athletes

A sports hernia is a common cause of groin pain in athletes, however until lately little has been known as to why they occur. Researchers presenting their study today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting in Baltimore suggest that a type of hip condition (Femoral Acetabular Impingement (FAI) might be a contributing cause.

13 Jul 2012

Negative suggestion can induce symptoms of illness

Negative suggestion can induce symptoms of illness. Nocebo effects are the adverse events that occur during sham treatment and/or as a result of negative expectations. While the positive counterpart—the placebo effect—has been intensively studied in recent years, the scientific literature contains few studies on nocebo phenomena.

13 Jul 2012

NICE: GPs must target diabetes prevention

Guidance for the prevention of type 2 diabetes out today from NICE urges GPs to step up efforts to get high-risk patients onto lifestyle intervention programmes. As trailed at the end of last year, the guidance recommends that GPs run checks on their practice register using a validated computerised diabetes risk tool and invite those falling into high-risk groups for a proper risk assessment, in line with the NHS Health Check programme.

12 Jul 2012

Early surgery best for infective endocarditis

Compared with conventional treatment, early surgery for patients with infective endocarditis and large vegetations significantly reduces the risk for death or embolic events by reducing the risk for systemic embolism, show results from a randomized trial.

12 Jul 2012

High-risk HPV may increase chances of second malignancy in oral cancer

The proportion of oral squamous cell carcinoma patients infected with the human papillomavirus could be around a third, with high-risk versions of the virus accounting for almost three-quarters of those affected, indicate Taiwanese study results.

12 Jul 2012

Disappointing result for acadesine

The adenosine-regulating agent acadesine does not reduce the occurrence of adverse outcomes in patients undergoing on-pump coronary artery bypass graft surgery, researchers say.

12 Jul 2012

Opioids for chronic noncancer pain discouraged

US experts have called for more selective and cautious opioid prescribing for chronic noncancer pain, because of concerns over misuse of the drugs and continued uncertainty over when and for how long they should be prescribed.

12 Jul 2012

Altered immune function in relatives of schizophrenia patients

Schizophrenia patients and their unaffected first-degree relatives exhibit immune system alterations compared with mentally healthy individuals, researchers report.

12 Jul 2012

$Ankle fracture severity linked to obesity$