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NIH awards VistaGen and NuPotential $500,000 grant to advance iPS stem cell technology

VistaGen Therapeutics, Inc. and NuPotential, Inc. today announced that the National Heart, Lung and Blood Institute of the U.S. National Institutes of Health (NIH) has awarded to the companies a grant of approximately $500,000 to accelerate development of novel and safer approaches to generate patient-specific induced pluripotent stem (iPS) cells for regenerative medicine, drug discovery and drug rescue.

13 Jan 2011

Investigators find reduction in STEMI rates, but slight increase in NSTEMI incidence rates

Coronary syndromes vary in severity, ranging from unstable angina, non-ST segment elevation myocardial infarction, to ST-segment elevation myocardial infarction, the most severe diagnosis. Little data exist about changing trends in acute myocardial infarction and whether death rates are increasing or decreasing.

13 Jan 2011

Minimal invasive valve surgery provides better outcomes in older patients: Mount Sinai study

The Annals of Thoracic Surgery has just published a study conducted at Mount Sinai Medical Center of Miami Beach reporting the outcomes of minimally invasive valve surgery versus traditional median sternotomy in patients 75 years of age or older. Minimally invasive valve surgery at Mount Sinai is performed through a small, 2-inch incision on the right side of the chest, and this was compared with the same kind of valve surgery done through a breastbone splitting approach.

13 Jan 2011

Health, social and economical consequences of sleep disorders: A controlled national study

"Snoring, sleep apnoea, and obesity-related respiratory difficulties are fairly common disorders that affect a large proportion of the population," according to Poul Jennum, Professor of Clinical Neurophysiology at the Center for Healthy Ageing at the University of Copenhagen Faculty of Health Sciences. He is head of the Danish Centre for Sleep Medicine, Glostrup Hospital, which treats patients from all over the country.

13 Jan 2011

MMRF, Synta collaborate for clinical development of ganetespib in multiple myeloma

The Multiple Myeloma Research Foundation (MMRF) today announced that it has entered into a joint collaboration with Synta Pharmaceuticals for the clinical development of ganetespib (formerly STA-9090) in patients with multiple myeloma.

13 Jan 2011

Emotional stress can affect motor coordination and other cerebellum-dependent cognitive functions: Study

Research conducted by Iaroslav Savtchouk, a graduate student, and S. June Liu, PhD, Associate Professor of Cell Biology and Anatomy at LSU Health Sciences Center New Orleans, has shown that a single exposure to acute stress affected information processing in the cerebellum - the area of the brain responsible for motor control and movement coordination and also involved in learning and memory formation.

13 Jan 2011

BIDMC scientist wins 2011 Pezcoller Foundation-AACR International Award for cancer research

Beth Israel Deaconess Medical Center cancer geneticist Pier Paolo Pandolfi, MD, PhD, is the recipient of the 2011 Pezcoller Foundation-AACR (American Association of Cancer Research) International Award for Cancer Research.

13 Jan 2011

Study highlights important clinical implications of miR-503 in diabetes-associated vascular complications

New research has found one of the smallest entities in the human genome, micro-RNA, could increase the risk of limb amputation in diabetic patients who have poor blood flow.

13 Jan 2011

New research paper reveals key lessons about origins of 2009 H1N1 pandemic

How Swine Flu Overturned the Understanding of Pandemic Outbreaks. As H1N1 'Swine Flu' returns to the national headlines a new research paper reveals the key lessons about the origins of the 2009 pandemic. The paper, published today in BioEssays, reveals how the pandemic challenges the traditional understanding of 'antigenic shift', given that the virus emerged from an existing influenza subtype.

13 Jan 2011

Scientists quantify amount of energy lost during sleep deprivation

American scientists have quantified for the first time ever the amount of energy lost during a night of sleep deprivation according to new research published in The Journal of Physiology.

13 Jan 2011

Aβ, tau and Fyn protein interactions may lead to brain dysfunction and AD

Though the cause of Alzheimer's disease still is unknown, recent studies have implicated three proteins strongly in its onset. New research from the University of Alabama at Birmingham, the Gladstone Institutes and the Baylor College of Medicine indicates that interactions between those three proteins might lead to brain dysfunction and AD in a mouse model of the disease.

13 Jan 2011

Cholesterol efflux capacity is more closely associated with protection against heart disease: Study

The discovery that high levels of high-density lipoprotein cholesterol is associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.

13 Jan 2011

Obesity in children today may contribute to 2-5 year decline in life expectancy

For the first time in history, the next generation will not live longer, or even as long, as their parents. "Diseases such as Type II diabetes, high blood pressure, heart conditions and joint deterioration - what were once considered 'adult' diseases - are regularly being diagnosed in children, due to the prevalence of obesity," said Jessica Bartfield, MD, internal medicine and medical weight-loss specialist at Gottlieb Memorial Hospital, part of the Loyola University Health System.

13 Jan 2011

Peninsula scientists to implement Policy Research Unit for early cancer screening and diagnosis

A team of researchers from the Peninsula College of Medicine and Dentistry are part of a wider group of researchers from leading institutions that will implement a -4.7m Policy Research Unit dedicated to achieving early cancer screening and diagnosis. The funding is provided over five years by the Department of Health and will be led by Queen Mary, University of London.

13 Jan 2011

Exposure to 'thirdhand smoke' poses additional health risks

Scientists are reporting that so-called "thirdhand smoke" - the invisible remains of cigarette smoke that deposits on carpeting, clothing, furniture and other surfaces - may be even more of a health hazard than previously believed. The study, published in ACS' journal, Environmental Science & Technology, extends the known health risks of tobacco among people who do not smoke but encounter the smoke exhaled by smokers or released by smoldering cigarette butts.

13 Jan 2011

BPA more harmful to women with hormonal and fertility imbalances

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), found higher Bisphenol A (BPA) levels in women with polycystic ovary syndrome (PCOS) compared to controls. Furthermore, researchers found a statistically significant positive association between male sex hormones and BPA in these women suggesting a potential role of BPA in ovarian dysfunction.

13 Jan 2011

Study indicates disease's underlying causes in mice, finds compounds that normalize Alzheimer's brain

A Blanchette Rockefeller Neurosciences Institute study published today in the Journal of Neuroscience reveals underlying causes for the degeneration of synapses in Alzheimer's Disease and identifies promising pharmaceutical solutions for the devastating condition that affects more than 5 million people in the United States.

12 Jan 2011

NSAIDs raise risk of heart disease: Study

A new study published online in the British Medical Journal explores the relative safety of non-steroidal anti-inflammatory medications (NSAIDs), commonly used to treat joint and muscle aches and pain and concludes that NSAIDs significantly increase the risk of cardiovascular events in patients who take them regularly.

12 Jan 2011

New Down syndrome non-invasive test for ‘mums-to-be’ on the horizon

According to experts a simple DNA test for Down syndrome could save nearly all pregnant women from invasive tests like amniocentesis. Usually 3% to 5% of pregnant women in the UK or some 30,000 women have to undergo invasive tests like amniocentesis that increases the risk of miscarriage to 1%. The new DNA blood test could bring this down to 0.1%, according to a study in the British Medical Journal.

12 Jan 2011

Fruit and vegetables gives more healthy golden glow than the sun

New research suggests eating vegetables gives you a healthy tan. The study, led by Dr Ian Stephen at The University of Nottingham, showed that eating a healthy diet rich in fruit and vegetables gives you a more healthy golden glow than the sun.

12 Jan 2011

Medical Research News

NIH awards VistaGen and NuPotential $500,000 grant to advance iPS stem cell technology

Investigators find reduction in STEMI rates, but slight increase in NSTEMI incidence rates

Minimal invasive valve surgery provides better outcomes in older patients: Mount Sinai study

Health, social and economical consequences of sleep disorders: A controlled national study

MMRF, Synta collaborate for clinical development of ganetespib in multiple myeloma

Emotional stress can affect motor coordination and other cerebellum-dependent cognitive functions: Study

BIDMC scientist wins 2011 Pezcoller Foundation-AACR International Award for cancer research

Study highlights important clinical implications of miR-503 in diabetes-associated vascular complications

New research paper reveals key lessons about origins of 2009 H1N1 pandemic

Scientists quantify amount of energy lost during sleep deprivation

Aβ, tau and Fyn protein interactions may lead to brain dysfunction and AD

Cholesterol efflux capacity is more closely associated with protection against heart disease: Study

Obesity in children today may contribute to 2-5 year decline in life expectancy

Peninsula scientists to implement Policy Research Unit for early cancer screening and diagnosis

Exposure to 'thirdhand smoke' poses additional health risks

BPA more harmful to women with hormonal and fertility imbalances

Study indicates disease's underlying causes in mice, finds compounds that normalize Alzheimer's brain

NSAIDs raise risk of heart disease: Study

New Down syndrome non-invasive test for ‘mums-to-be’ on the horizon

Fruit and vegetables gives more healthy golden glow than the sun

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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