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New method to generate custom-made platelets from skin cells

Skin cells from humans can be revamped into pro-clotting cells called platelets, according to a study published on November 22 in the Journal of Experimental Medicine.

23 Nov 2010

New findings shed light on people's response to daylight and biological clock

Fresh insight into how biological clocks adjust to having less sunlight in the winter could help us better understand the impact of jet lag and shift work.

23 Nov 2010

Most patients taking anti-depressants give up treatment: Study

Most patients who take anti-depressants give up their treatment in less than six months, the minimum period recommended for treating severe depression and other derived pathologies. This is the conclusion of a new study carried out by Catalan researchers, which reveals that only 25% continue their treatment for more than 11 months.

23 Nov 2010

Rates of hospital emergency department use greater among women and low-income, older and rural Americans

Americans age 18 and older made over 98 million trips to hospital emergency departments in 2008 for problems ranging from broken bones to heart attacks, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. This represents 78 percent of the overall nearly 125 million visits that year.

23 Nov 2010

CEL-SCI holds clinical investigator meeting for Multikine Phase III clinical trial in head, neck cancer

CEL-SCI Corporation today announced that the Company held a clinical investigator meeting during the week of November 14th for its Phase III clinical trial of Multikine®, the Company's flagship immunotherapy developed as a first-line standard of care in treating head and neck cancer.

23 Nov 2010

Researchers identify trigger mechanism for quality control checkpoint in cell division process

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report that they have identified a previously undiscovered trigger mechanism for a quality control checkpoint at the very end of the cell division process in a paper to be published in the November 29 issue of The Journal of Cell Biology and online today.

23 Nov 2010

Scientists make breakthrough in techniques for exploring faults in 'smooth' muscles

Clues to the causes of serious, and often fatal, diseases and conditions, such as heart disease, stroke and high blood pressure, are being investigated at the Universities of Strathclyde and Glasgow, both in Scotland, with the use of a -1 million grant.

23 Nov 2010

Researchers investigate ways to counteract unhealthy effects of fat

A fat yet muscular mouse is helping researchers learn whether more muscle improves the cardiovascular health of obese individuals. We are looking for ways to counteract the unhealthy effects of fat, said Dr. David Stepp, vascular biologist at the Medical College of Georgia Vascular Biology Center and co-director of MCG's Diabetes & Obesity Discovery Institute.

23 Nov 2010

Largest genomic study of human medulloblastomas

Medulloblastomas are the most common malignant brain tumors of childhood, with 40 to 50 percent overall mortality. One of the greatest challenges in treating them is that they vary substantially from patient to patient. In the largest genomic study of human medulloblastomas to date, researchers from Children's Hospital Boston, together with collaborators, have identified six subtypes with distinct molecular "fingerprints" that will improve doctors' ability to direct and individualize treatment.

23 Nov 2010

Researcher develops new method that causes cancer cells to self-destruct

Tulane University researcher W T. Godbey has developed a treatment for cancer using a method that causes cancer cells to self-destruct while sparing surrounding healthy cells.

23 Nov 2010

Late-preterm babies at increased risk for cognitive, emotional problems

Late-preterm babies - those born between 34 and 36 weeks - are at an increased risk for cognitive and emotional problems, regardless of maternal IQ or demographics, according to new research published by Michigan State University researchers in the current edition of the journal Pediatrics.

23 Nov 2010

Agilent releases GeneSpring GX 11.5 multi-omics bioinformatics system

Agilent Technologies Inc. today introduced GeneSpring GX 11.5, an expansion of its popular bioinformatics software into visualizing and analyzing multiple types of biological data. GeneSpring GX 11.5 now interprets exon microarray, proteomics and metabolomics experiments together for the first time, using a familiar interface.

23 Nov 2010

Rate, direction of axon growth in spinal cord can be controlled, study shows

Both the rate and direction of axon growth in the spinal cord can be controlled, according to new research by USC College's Samantha Butler and her collaborators.

23 Nov 2010

New method to reverse age-related decline in vision

Elderly adults can improve their vision with perceptual training, according to a study from the University of California, Riverside and Boston University that has implications for the health and mobility of senior citizens.

23 Nov 2010

Dangers of excess fructose

More and more people have become aware of the dangers of excessive fructose in diet. A new review on fructose in an upcoming issue of the Journal of the American Society of Nephrology (JASN) indicates just how dangerous this simple sugar may be.

23 Nov 2010

Australian university students a ‘stressed out’ bunch: Study

According to the latest findings the rates of serious mental illness are more than five times higher among university students than in the general population. The study conducted by researchers at University of Queensland was published in the latest issue of Australian Psychologist. It also found that rate of pyschological distress among university students is almost three times higher than in the general population.

22 Nov 2010

Profil Institute expands capabilities to detect cardiac safety signals in diabetes and obesity clinical trials

Profil™ Institute for Clinical Research, Inc., a company specializing in early phase clinical trials for diabetes and obesity, announced today the expansion of its capabilities for cardiac safety and cardiovascular efficacy studies in the company's early phase diabetes and obesity clinical trials.

22 Nov 2010

Variation at gene locus associated with greater reproductive success

Since 1871, when Charles Darwin wrote The Descent of Man, it has been widely accepted that "Variability is the necessary basis for the action of selection." Variability is associated with the ability to adapt, which is clearly beneficial at a species level. But there is increasing evidence that genetic variability may also give rise to advantages at the level of the individual.

22 Nov 2010

New study links high prevalence of insomnia and poor quality of life in software engineers

Insomnia is bad news for software engineers' quality of life and deserves greater recognition and attention, according to new research by Sara Sarrafi Zadeh and Khyrunnisa Begum from the University of Mysore in India. Their work shows that poor sleep has a bearing on quality of life - affecting physical and mental health in particular - in this group with high levels of job-related stress. Their paper is published online in Springer's journal Applied Research in Quality of Life.

22 Nov 2010

ImmunGene awarded $244,479 therapeutic discovery project grant under PPACA 2010

ImmunGene, Inc., a privately held drug development company focused on targeted antibody therapeutics with numerous anti-cancer functions built into a single therapy, announced today that it has received a $244,479 grant under The Patient Protection and Affordable Care Act of 2010 (PPACA). The grant was related to the development of ImmunGene's technology which is based on antibody-cytokine fusions that have demonstrated targeted toxicity and added tumor benefits.

22 Nov 2010