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f-star and Boehringer Ingelheim enter joint discovery agreement for new antibody-derived therapeutic products

f-star Biotechnologische Forschungs-und Entwicklungsges.m.b.H today announced the signing of a collaboration and license agreement with Boehringer Ingelheim for joint discovery of new antibody-derived therapeutic products based on f-star's Modular Antibody Technology.

22 Nov 2010

Researchers develop three-dimensional cancer cell from normal human tissue in culture dish

Researchers at the Stanford University School of Medicine have successfully transformed normal human tissue into three-dimensional cancers in a tissue culture dish for the first time. Watching how the cells behave as they divide and invade surrounding tissue will help physicians better understand how human cancers act in the body. The new technique also provides a way to quickly and cheaply test anti-cancer drugs without requiring laboratory animals.

22 Nov 2010

Study finds common gene variant in African Americans increases risk of kidney disease

In African Americans with kidney disease related to hypertension (high blood pressure), a common gene variant is associated with a sharply increased risk of progressive kidney disease, according to a study presented at the American Society of Nephrology's 43rd Annual Meeting and Scientific Exposition. End Stage Renal Disease (ESRD) associated with hypertension occurs in the African American population at a rate 13.1 times greater than that of their white counterparts.

22 Nov 2010

Research indicates possible danger of cancerous tissue development by using stem cells

Research work carried out at the Hebrew University of Jerusalem arouses a cautionary warning in the growing field of the development of stem cells as a means for future treatment of patients through replacement of diseased or damaged tissues by using the patient's own stem cells. The research indicates a possible danger of cancerous tissue development in the use of such cells.

22 Nov 2010

Researchers reconstitute first step of break repair in cancerous cells

What prompts normal cells to transform themselves into cancerous cells. Researchers from Texas institutions, including the UT Health Science Center San Antonio, have identified factors in the very first step of the process and reconstituted this first step in the test tube. The latter accomplishment was reported Sunday [Nov. 21] in the top-tier journal Nature Structural & Molecular Biology.

22 Nov 2010

Inexpensive intervention helps patients with hypertension-associated kidney disease

In patients with kidney disease, the Western diet produces an acidic environment in the body that has numerous negative effects and worsens with age as kidney function declines.

21 Nov 2010

Presence of albumin in urine predicts cognitive decline: Study

A new study has found that low amounts of albumin in the urine, at levels not traditionally considered clinically significant, strongly predict faster cognitive decline in older women.

21 Nov 2010

CRE pleased with FDA's attention to DQA petition

Out of all the studies cited by the FDA regarding the health effects of menthol that the only end points of any potential significance dealt with smoking initiation/cessation.

20 Nov 2010

First international study to examine human developmental effects of environmental exposure to e-waste

A new international population study, led by the University of Cincinnati, will be the first to examine the human developmental effects of environmental exposure to the complex metal mixture found in electronic waste (e-waste).

20 Nov 2010

Potassium citrate effective for prevention and treatment of osteoporosis: Study

The Western diet creates an acidic environment in the body that removes calcium from bones and may contribute to the development of osteoporosis. Healthy adults who consume the standard US diet sustain a chronic, low-grade state of acidosis that worsens with age as kidney function declines, limiting urinary acid excretion. Reto Krapf, MD (University of Basel, in Bruderholz/Basel, Switzerland) and colleagues designed a study to see if daily alkali as potassium citrate supplement tablets might neutralize these effects.

20 Nov 2010

Study finds gender difference in brain function of schizophrenics

Schizophrenia is a mental disorder that differs between the sexes in terms of age at onset, symptomatology, response to medication, and structural brain abnormalities. Now, a new study from the Universit- de Montr-al shows that there is gender difference between men and women's mental ability with women performing better than men.

20 Nov 2010

K.U.Leuven researchers receive ERC Advanced Grants

K.U.Leuven researchers Peter Carmeliet and Bart De Strooper have both been awarded Advanced Grants from the European Research Council. ERC Advanced Grants are the most prestigious European research grants, spanning a period of 5 years. Peter Carmeliet of the VIB Vesalius Research Centre, K.U.Leuven, will receive approximately 2.5 million euro for research focused on stopping the energy supply into blood vessels.

20 Nov 2010

Genetic differences impact winter vitamin D status

Vitamin D is somewhat of an unusual "vitamin," because it can be made in the body from sunlight and most foods do not contain vitamin D unless added by fortification. Synthesis of vitamin D in the body requires exposure to ultraviolet light and can be influenced by genetics, skin color, and sun exposure.

20 Nov 2010

Study sheds light on poorly understood aspect of interaction of HIV with natural killer cells

Natural killer cells are major weapons in the body's immune system. They keep the body healthy by knocking off tumors and cells infected with viruses, bombarding them with tiny lethal pellets. But natural killer cells are powerless against HIV, a fact that has bedeviled science for over 20 years.

20 Nov 2010

New I-SPY 2 study to evaluate effectiveness of medical treatment for breast cancer

A clinical trial that aims to speed up the study of new treatments for certain subtypes of breast cancer now has a designated study site at the Diane O'Connor Thompson Breast Center at the University of Colorado Hospital.

20 Nov 2010

Early nephrology care associated with lower mortality and incidence of end stage renal disease

Earlier care from a nephrologist reduces the chance of kidney patients developing end-stage renal disease and lowers their risk of death during the first year of dialysis, according to a study by the University of Michigan Kidney Epidemiology & Cost Center.

20 Nov 2010

Scientists identify gene variants associated with eating disorder

Scientists at The Children's Hospital of Philadelphia have identified both common and rare gene variants associated with the eating disorder anorexia nervosa.

20 Nov 2010

Children with higher waist circumferences more likely to have heart-related disorders: Researchers

In a study of more than 4,500 children, researchers found those with higher waist circumferences had significantly higher pulse pressures, which is known to increase the risk of heart-related disorders, according to an abstract presented today at the American Society of Nephrology's Renal Week conference in Denver.

20 Nov 2010

Scientist suggests functional amino acids play a critical role in human health

Functional amino acids play a critical role in the development of both animals and humans, according to a Texas AgriLife Research scientist.

20 Nov 2010

USC Norris designated Phase I Clinical Trial Center of Excellence

The USC Norris Comprehensive Cancer Center (USC Norris) has been designated a Phase I Clinical Trial Center of Excellence by global pharmaceutical company Bristol-Myers Squibb Company. The collaboration will bring a number of new phase I clinical trials to USC Norris, and will enable the cancer center's clinical and basic scientists to provide guidance in early phase drug development and trial design.

20 Nov 2010

Medical Research News

f-star and Boehringer Ingelheim enter joint discovery agreement for new antibody-derived therapeutic products

Researchers develop three-dimensional cancer cell from normal human tissue in culture dish

Study finds common gene variant in African Americans increases risk of kidney disease

Research indicates possible danger of cancerous tissue development by using stem cells

Researchers reconstitute first step of break repair in cancerous cells

Inexpensive intervention helps patients with hypertension-associated kidney disease

Presence of albumin in urine predicts cognitive decline: Study

CRE pleased with FDA's attention to DQA petition

First international study to examine human developmental effects of environmental exposure to e-waste

Potassium citrate effective for prevention and treatment of osteoporosis: Study

Study finds gender difference in brain function of schizophrenics

K.U.Leuven researchers receive ERC Advanced Grants

Genetic differences impact winter vitamin D status

Study sheds light on poorly understood aspect of interaction of HIV with natural killer cells

New I-SPY 2 study to evaluate effectiveness of medical treatment for breast cancer

Early nephrology care associated with lower mortality and incidence of end stage renal disease

Scientists identify gene variants associated with eating disorder

Children with higher waist circumferences more likely to have heart-related disorders: Researchers

Scientist suggests functional amino acids play a critical role in human health

USC Norris designated Phase I Clinical Trial Center of Excellence

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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