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Parkinson's medication produces serious side effects in the form of involuntary, jerky movements: Research

One in every 100 elderly people suffers from Parkinson's disease, a disease of the nervous system with symptoms including stiffness and shaking. The standard medication used to treat Parkinson's is Levodopa, a drug that initially has major benefits but can later also produce serious side effects in the form of involuntary, jerky movements. A research group at Lund University has now found a way to study what it is in the brain that causes these side effects.

20 Jul 2010

BC-CfE study suggests HAART may prevent transmission, spread of HIV

The BC Centre of Excellence in HIV/AIDS published an important study today in the globally respected Lancet medical journal. The study strongly reinforces the view that the benefits of highly active antiretroviral therapy extend beyond treatment of the virus to significantly preventing the transmission and spread of HIV.

20 Jul 2010

Cash rewards help combat STIs in rural Africa, study finds

Giving out cash can be an effective tool in combating sexually transmitted infections in rural Africa, according to a new study conducted jointly by researchers at the University of California, Berkeley, the Development Research Group at the World Bank and the Ifakara Health Institute in Tanzania.

20 Jul 2010

'Sloppy' practices at brain imaging center could have far-reaching repercussions for brain research

The Los Angeles Times: "The suspension of some research at a prominent Columbia University brain-imaging lab because of sloppy practices could have repercussions beyond that laboratory, potentially affecting brain-imaging studies nationwide and raising questions about the safety of participants, research experts said Saturday.

20 Jul 2010

Researchers discover new gene regulation, DNA behavior of breast cancer cells

Cancer researchers have discovered a previously unknown type of gene regulation and DNA behavior in breast cancer cells that may lead to better insight about environmental exposure to estrogen-like compounds. A new study, published in the journal Genome Research by researchers at The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James), provides the first evidence that cells can regulate many genes at once by looping their DNA, contributing to cancer when it goes awry. In this study, the gene regulation was discovered in breast cancer cells as a response to the hormone estrogen and resulted in the silencing of 14 genes at one time.

20 Jul 2010

FDA joins Tox21 collaboration for improved chemical screening

The U.S. Environmental Protection Agency (EPA), the National Institute of Environmental Health Sciences National Toxicology Program (NTP) and the National Institute of Health Chemical Genomics Center (NCGC) welcome the U.S. Food and Drug Administration (FDA) to the Tox21 collaboration. The Tox21 collaboration merges federal agency resources (research, funding and testing tools) to develop ways to more effectively predict how chemicals will affect human health and the environment. The collaboration was established in 2008 to develop models that will be able to better predict how chemicals will affect humans. FDA will provide additional expertise and chemical safety information to improve current chemical testing methods.

20 Jul 2010

Researchers monitor stress during a real-time war to refine PTSD therapy

Psychologists aren't usually called to the battlefield, but the 2008-09 Gaza War gave Tel Aviv University researchers a unique picture of how anxiety manifests during stressful situations.

20 Jul 2010

Pharma industry leaders reduce R&D time, costs with aspenONE Process Development software

Aspen Technology, Inc., a leading provider of software and services to the process industries, today announced that GlaxoSmithKline, AstraZeneca and other pharmaceutical industry leaders are reducing their research and development time and costs using newly patented technology that is part of AspenTech's aspenONE Process Development for Pharmaceuticals software.

19 Jul 2010

Visage Imaging releases Amira 5.3 single platform brain imaging tool

Visage Imaging®, Inc., a wholly owned subsidiary of Pro Medicus Ltd., is pleased to announce the immediate release of Amira 5.3, a new major version of its market-leading software platform for visualizing, analyzing, and presenting complex 3D and 4D biomedical data.

19 Jul 2010

Novo Nordisk recruits 60,000th patient in world's largest observational study in insulin therapy

Today, Novo Nordisk announced the landmark recruitment of the 60,000th patient in the A1chieve(R) study - an observational study designed to investigate the effects of modern insulins in the management of type 2 diabetes.

From Novo Nordisk 19 Jul 2010

Study evaluates immunization benefits of dissolving microneedles

A new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could allow persons without medical training to painlessly administer vaccines - while providing improved immunization against diseases such as influenza.

19 Jul 2010

Three different methods for accurately measuring breast density

Two new studies announced this week have tested three different methods for accurately measuring breast density -- the relative portion of tissue to fat in a woman's breasts and a strong indicator of breast cancer risk.

19 Jul 2010

Tet 1 protein helps stem cells renew themselves and stay pluripotent: Researchers

Take a skin cell from a patient with Type 1 diabetes. Strip out everything that made it a skin cell, then reprogram it to grow into a colony of pancreatic beta cells. Implant these into your patient and voilà! She's producing her own insulin like a pro.

19 Jul 2010

Researchers to receive $1.2M from Susan G. Komen for the Cure for breast cancer research

Four researchers from Detroit, Michigan's Barbara Ann Karmanos Cancer Institute and Wayne State University will receive a total of $1.2 million from Susan G. Komen for the Cure to help advance research to better detect, prevent and eliminate breast cancer. The $1.2 million awarded to these outstanding scientists is part of the $59 million portfolio of research grants that Susan G. Komen for the Cure has awarded this year alone to scientists across the globe to help accelerate innovative breast cancer research.

17 Jul 2010

Purdue Research Foundation, Techshot partner to accelerate development of emerging technology companies

Officials from Purdue Research Foundation and Techshot Inc. announced Friday that they will partner on a program designed to accelerate the development of emerging technology companies by leveraging Techshot's unique technology commercialization capabilities.

17 Jul 2010

GABA disrupts working memory in neurofibromatosis type 1 patients

Imagine if your brain lost its working memory - the ability to hold and manipulate information in your mind's eye. That's the plight faced by millions of people with neurofibromatosis type 1, or NF1. The genetic condition affects one in 3,500 people and is the most common cause of learning disabilities.Now a UCLA research team has uncovered new clues about how NF1 disrupts working memory. Published in the July 12 online edition of Proceedings of the National Academy of Sciences, the findings suggest a potential drug target for correcting NF1-related learning disabilities.

17 Jul 2010

Lorillard calls upon FDA TPSAC to employ dispassionate science in evaluation of menthol in cigarettes

With the words of Food and Drug Commissioner Margaret Hamburg on the screen beside him, a Lorillard Tobacco Company scientist today called upon the FDA's Tobacco Products Scientific Advisory Committee (TPSAC) to employ a "truly science-based, data-driven" process in its evaluation of menthol in cigarettes. Earlier this week Hamburg made headlines when she told an FDA science panel to "Follow the science wherever it leads and the rest will fall into place."

17 Jul 2010

AMPK may regulate epigenetic mechanism: Research

AMP-activated protein kinase, or AMPK, is a master regulator protein of metabolism that is conserved from yeast to humans. When a cell is low on fuel, AMPK shuts down processes that use energy and turns on processes that produce energy.Biologists have been studying how AMPK works for several decades and know that once it is activated, AMPK turns on a large number of genes by passing the "make more energy" message through numerous signaling cascades in the cell. What was not known, until now, was that AMPK also works via an epigenetic mechanism to slow down or stop cell growth.

17 Jul 2010

Resveratrol concentration impacts cancer risk mitigation: Study

Agricultural Research Service (ARS) chemist Thomas Wang, who specializes in cancer prevention research, has reported evidence that for some dietary compounds, length of exposure over time may be key to whether or not ingestion leads to a beneficial, or detrimental, effect.Scientists do not know exactly why one person develops cancer and another does not. But they do know that certain nutrients might increase or decrease cancer risk. There are "layers" of factors involved in the development of cancer, and Wang is studying the layers involving peoples' diet complexity and gene expression.

17 Jul 2010

ICON opens purpose-built clinical pharmacology unit within CMFT campus

ICON plc,, a global provider of outsourced development services to the pharmaceutical, biotechnology and medical device industries, today announced the official opening of a purpose-built clinical pharmacology unit within the Central Manchester University Hospitals Foundation Trust (CMFT) campus in Manchester, UK. Initial studies in the unit utilising translational medicine methodologies to expedite drug development projects began in June, and already 110 volunteers have participated in studies there.

17 Jul 2010

Medical Research News

Parkinson's medication produces serious side effects in the form of involuntary, jerky movements: Research

BC-CfE study suggests HAART may prevent transmission, spread of HIV

Cash rewards help combat STIs in rural Africa, study finds

'Sloppy' practices at brain imaging center could have far-reaching repercussions for brain research

Researchers discover new gene regulation, DNA behavior of breast cancer cells

FDA joins Tox21 collaboration for improved chemical screening

Researchers monitor stress during a real-time war to refine PTSD therapy

Pharma industry leaders reduce R&D time, costs with aspenONE Process Development software

Visage Imaging releases Amira 5.3 single platform brain imaging tool

Novo Nordisk recruits 60,000th patient in world's largest observational study in insulin therapy

Study evaluates immunization benefits of dissolving microneedles

Three different methods for accurately measuring breast density

Tet 1 protein helps stem cells renew themselves and stay pluripotent: Researchers

Researchers to receive $1.2M from Susan G. Komen for the Cure for breast cancer research

Purdue Research Foundation, Techshot partner to accelerate development of emerging technology companies

GABA disrupts working memory in neurofibromatosis type 1 patients

Lorillard calls upon FDA TPSAC to employ dispassionate science in evaluation of menthol in cigarettes

AMPK may regulate epigenetic mechanism: Research

Resveratrol concentration impacts cancer risk mitigation: Study

ICON opens purpose-built clinical pharmacology unit within CMFT campus

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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