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Palliative care continues to play vital role in the continuum of cancer care: Study

A study from The University of Texas M. D. Anderson Cancer Center reports that cancer centers in the United States provide patients and their families with palliative care, though the depth, range and integration of programs and services widely vary.

18 Mar 2010

Researchers find retinoic acid regulates SHF tissue formation

Researchers at the Keck School of Medicine of the University of Southern California have identified a key cellular mechanism that guides embryonic heart tissue formation-a process which, if disrupted, can lead to a number of common congenital heart defects.

18 Mar 2010

Low vitamin D levels in African American children connected with high asthma rates

Researchers at Children's National Medical Center have discovered that African American children with asthma in metropolitan Washington, DC, are significantly more likely to have low levels of vitamin D than healthy African American children.

18 Mar 2010

Combination of gemcitabine and cisplatin limits the progression of endometrial cancer: Study

Researchers from The University of Texas M. D. Anderson Cancer Center report that in a small study of women with advanced or recurrent endometrial cancer, gemcitabine and cisplatin, when used in combination, produced a response rate in fifty percent of patients.

18 Mar 2010

LSUHSC: Differences in drug metabolism can lead to differences in the effectiveness of candidate drug

Research led by Wayne L. Backes, PhD, Professor of Pharmacology and Associate Dean for Research at LSU Health Sciences Center New Orleans School of Medicine, has found that drug metabolism depends not only upon which enzymes are present in an individual, but also how they interact, and that can be the difference in whether a drug is safely eliminated from the body or is converted into a toxic or carcinogenic byproduct.

18 Mar 2010

Early baldness may not be associated with risk of prostate cancer

Men who start losing their hair at an early age may be less likely to develop prostate cancer in the future, new research suggests.

18 Mar 2010

Studies link atmospheric CO pollution to adverse cardiovascular outcomes, cardiac mortality

In the healthy rat, prolonged exposure to carbon monoxide (CO) under conditions that mimic urban pollution leads to changes to cardiac morphology and function. Compensatory mechanisms develop in these animals to sustain normal cardiac activity, but they become more vulnerable to heart disease.

18 Mar 2010

Toxins released by certain microalgae can contaminate seafood and become toxic to humans

Toxins released by certain microalgae can contaminate fish and shellfish which then become toxic to humans. Researchers from CNRS and CEA have, for the first time, identified the mechanisms of action of two of these toxins.

18 Mar 2010

PPD, Southern Research Institute collaborate in pandemic and seasonal influenza vaccine research

PPD and Southern Research Institute today announced they have formed a collaborative agreement in pandemic and seasonal influenza vaccine research and development to provide clients a full spectrum of influenza vaccine development services by collaborating on client bids and projects.

18 Mar 2010

Genes linked to ulcerative colitis identified

A study of the human genome led by Cedars-Sinai researchers has now identified genes linked to ulcerative colitis, offering clues as to what causes the condition and potential avenues for new therapies to treat the disease.

18 Mar 2010

Blocking GM-CSF could reduce inflammation and deleterious effects of cigarette smoke exposure

Researchers in Australia have demonstrated that blocking a certain protein can reduce or prevent cigarette smoke-induced lung inflammation in mice. Inflammation underlies the disease process of chronic obstructive pulmonary disease (COPD) and many other smoking-related ailments.

18 Mar 2010

CNS Network purchases Logos Technologies' pro-active EDC system for streamlining clinical trials

It is announced today that CNS Network has purchased ALPHADAS®, Logos Technologies Inc’s early phase, e-source data capture system and site automation tools to accelerate and streamline its clinical trials. ALPHADAS is to be implemented in their Orange County Research Center, California, USA.

17 Mar 2010

PAREXEL genotypes over 10,000 potential study participants to identify 400 CYP2D6 poor metabolizers

PAREXEL International Corporation, a leading global biopharmaceutical services provider, today announced that it has completed a large and complex pharmacogenetics-based early phase study. The study was conducted in a healthy volunteer population of poor metabolizers of Cytochrome P450 2D6 (CYP2D6), an important enzyme involved in the metabolism of drugs. The study monitored the QTc interval following administration of a neurological treatment, which has been shown to have a higher drug exposure in poor metabolizers of CYP2D6.

From Parexel 17 Mar 2010

Study analyzes mortality rates of patients after coronary angioplasty

A team of Mayo Clinic researchers have found that cardiac rehabilitation is associated with significantly reduced mortality rates for patients who have had stents placed to treat blockages in their coronary arteries.

17 Mar 2010

Test tube studies offer new hope for Alzheimer’s patients

A team of scientists from SLU in Uppsala and University of Cambridge have discovered a molecule that can prevent a toxic protein involved Alzheimer's disease from building up in the brain.

17 Mar 2010

Study provides new perspective on cell movements

When cells move about in the body, they follow a complex pattern similar to that which amoebae and bacteria use when searching for food, a team of Vanderbilt researchers have found.

17 Mar 2010

Boosting radiation dose for prostate cancer patients does not increase severity of side effects

Boosting the radiation dose given to prostate cancer patients to a level that cut tumor recurrence in half did not increase the severity of side effects reported by patients up to a decade later. The study led by Massachusetts General Hospital Cancer Center researchers also found that patients characterized the impact of continuing side effects on their quality of life as considerably less bothersome than would be expected, based on earlier studies.

17 Mar 2010

Booster shot appears to improve TB resistance in previously vaccinated adults

A booster shot appears to improve tuberculosis (TB) resistance in previously vaccinated adults, according to new research in South Africa.

17 Mar 2010

Obesity and passive smoking are risk factors for elevated umbilical cord neonatal immature

Babies born to mothers with obesity and exposed to passive smoking are more likely to have health problems than others. This conclusion is based on evidence of elevated levels of nucleated red blood cells in the umbilical cord reported in the International Journal of Food Safety, Nutrition and Public Health.

17 Mar 2010

Pfizer-FRSQ-MSSS Chronic Disease Fund for chronic-disease prevention and management initiatives

The Fonds de la recherche en santé du Québec in partnership with the Ministère de la Santé et des Services sociaux and Pfizer Canada, is announcing the creation of the Pfizer-FRSQ-MSSS Chronic Disease Fund. Established with an investment of $5 million from Pfizer Canada, this research grant program, coordinated by the FRSQ, is open to Quebec-based researchers who work in collaboration with health professionals.

17 Mar 2010

Medical Research News

Palliative care continues to play vital role in the continuum of cancer care: Study

Researchers find retinoic acid regulates SHF tissue formation

Low vitamin D levels in African American children connected with high asthma rates

Combination of gemcitabine and cisplatin limits the progression of endometrial cancer: Study

LSUHSC: Differences in drug metabolism can lead to differences in the effectiveness of candidate drug

Early baldness may not be associated with risk of prostate cancer

Studies link atmospheric CO pollution to adverse cardiovascular outcomes, cardiac mortality

Toxins released by certain microalgae can contaminate seafood and become toxic to humans

PPD, Southern Research Institute collaborate in pandemic and seasonal influenza vaccine research

Genes linked to ulcerative colitis identified

Blocking GM-CSF could reduce inflammation and deleterious effects of cigarette smoke exposure

CNS Network purchases Logos Technologies' pro-active EDC system for streamlining clinical trials

PAREXEL genotypes over 10,000 potential study participants to identify 400 CYP2D6 poor metabolizers

Study analyzes mortality rates of patients after coronary angioplasty

Test tube studies offer new hope for Alzheimer’s patients

Study provides new perspective on cell movements

Boosting radiation dose for prostate cancer patients does not increase severity of side effects

Booster shot appears to improve TB resistance in previously vaccinated adults

Obesity and passive smoking are risk factors for elevated umbilical cord neonatal immature

Pfizer-FRSQ-MSSS Chronic Disease Fund for chronic-disease prevention and management initiatives

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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