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Deficiencies in DNA loop formation can cause multiple diseases: Research

The genes that are responsible for maintaining each cell type form DNA loops that link control elements for these genes. This surprising genome structure is generated and reinforced by two essential protein complexes that bridge the loops and contribute to proper gene regulation.

19 Aug 2010

Scientists study yeast to understand human pathologies affecting male fertility

Men and yeast have something in common: they use the same molecular process to ensure the integrity of their gene pool during reproduction. This is a recent finding by researchers from CNRS, Inserm and the Université Joseph Fourier in Grenoble. The scientists are therefore set on studying yeast in order to shed light on the numerous cases of male infertility related to the malfunction of this process during spermatogenesis.

19 Aug 2010

Podiatrist reduces leg amputation risk in diabetics: Study

People with diabetic foot problems can lower their risk of leg amputation by relying on coordinated care that includes a podiatrist, according to a recent study. For instance, those with diabetes-related foot ulcers can reduce their risk of amputation by 31 percent.

19 Aug 2010

U-M research results show potential for discovering new avenues for anti-aging drugs

A team of University of Michigan scientists has found that suppressing a newly discovered gene lengthens the lifespan of roundworms. Scientists who study aging have long known that significantly restricting food intake makes animals live longer. But the goal is to find less drastic ways to achieve the same effect in humans someday. The U-M results offer promising early evidence that scientists may succeed at finding targets for drugs that someday could allow people to live longer, healthier lives.

19 Aug 2010

New study sheds light on recovery from intoxication

A new study shows the impact of alcohol intoxication on reasoning and problem-solving abilities and may explain why some people feel they have recovered enough to drive after drinking. The research, led by Peter J. Snyder, PhD, vice president of research for Lifespan, is the first to explore how these cognitive abilities are impacted during both rising and declining blood alcohol concentrations, at matched blood alcohol level concentrations, and how self-evaluation of recovery differs from actual recovery from impairment.

19 Aug 2010

U.S. children and adolescents become fatter over the last decade: Study

Overweight American children and adolescents have become fatter over the last decade, according to researchers at the Johns Hopkins Bloomberg School of Public Health and National Institute on Aging (NIA). They examined adiposity shifts across socio-demographic groups over time and found U.S. children and adolescents had significantly increased adiposity measures such as body mass index (BMI), waist circumference (WC) and triceps skinfold thickness (TST).

19 Aug 2010

Overweight, smoking and lack of exercise linked to frequent headaches in teens

Teens who are overweight, get little exercise or who smoke may be more likely to have frequent headaches and migraines than teens with none of these factors, according to a study published in the August 18, 2010, online issue of Neurology®, the medical journal of the American Academy of Neurology.

19 Aug 2010

More young people are losing their hearing: Study

A new study from US reveals that hearing loss is becoming more common among young people. The study reports that 1 in 5 adolescents now have some hearing problems, particularly in perceiving high-frequency sounds. Researchers say loud music could be one of the reasons for this.

18 Aug 2010

Rush University Medical Center tests new drug therapy for West Nile fever

Neurological and infectious disease experts at Rush University Medical Center are testing a new drug therapy for the treatment of individuals with West Nile fever or suspected central nervous system infection due to the West Nile virus. Rush is the only site in the Midwest enrolling patients into the $50 million dollar, NIH-funded, Phase II clinical trial called PARADIGM.

18 Aug 2010

Study on differential aspects of cardiac insufficiency due to high blood pressure amongst women and men

Doctor Elena Zubillaga studied 109 women and 120 men admitted to hospital with a cardiac insufficiency solely due to high blood pressure. More concretely, she analysed the clinical, biochemical and ecocardiographical differences between the patients, depending on their sex. She also made reference to the data provided by serum markers for the metabolism of the collagen in the heart and the systolic function or contraction of the latter, as alterations taking place in the metabolism of myocardial collagen are associated with certain clinical situations.

18 Aug 2010

MDA awards $14.1 million in new grants to advance treatments and cures for muscle diseases

The Muscular Dystrophy Association, which has invested almost $39 million in 2010 in worldwide research seeking treatments and cures for muscle diseases, today announced that it has awarded $14.1 million in new grants.

18 Aug 2010

Marriage and social support reduce psychological stress

Being married has often been associated with improving people's health, but a new study suggests that having that long-term bond also alters hormones in a way that reduces stress.

18 Aug 2010

Brain trauma in sports associated with motor neuron disease, researchers find

The Center for the Study of Traumatic Encephalopathy at Boston University School of Medicine and Department of Veterans Affairs announced today that they have provided the first pathological evidence that repetitive head trauma experienced in collision sports is associated with motor neuron disease, a neurological condition that affects voluntary muscle movements.

18 Aug 2010

Health care system delay increases death risk in heart attack patients

For patients with a certain type of heart attack, delay in the time between first contact with emergency medical service to initiation of therapy such as balloon angioplasty is associated with an increased risk of death, according to a study in the August 18 issue of JAMA.

18 Aug 2010

$Study finds link between osteoporosis, fracture$

Study finds link between osteoporosis, fracture

An international study of more than 60,000 women has drawn new light on the relationship between osteoporosis and fractures.Scientists call for more to be done to identify and treat patients at the highest risk of fractures.Osteoporosis is more common in women who have fractured bones when they were younger and they experience a similar loss in health-related quality of life as those with arthritis, lung disease, diabetes and other chronic diseases.

18 Aug 2010

AACR opens nominations for awards recognizing excellence in cancer research

The American Association for Cancer Research is currently accepting nominations for awards recognizing excellence in cancer research, to be presented at the 102nd AACR Annual Meeting 2011, held in Orlando, Fla., from April 2 to 6.

18 Aug 2010

Research shows mutation in Prox1 gene may lead to memory, learning problems

St. Jude Children's Research Hospital investigators showed a gene named Prox1 is a key player in normal development of a brain structure crucial for learning and memory and remains active throughout life, nurturing the cells vital for making new memories.This study focused on a small region of the hippocampus known as the dentate gyrus, a brain structure needed for memory and learning that is home to the subgranular zone where the neural stem cells destined to become granule cells are housed. The dentate gyrus is one of two regions of the adult brain where neural stem cells continue to produce the precursor cells that ultimately differentiate into neurons.

18 Aug 2010

Researcher unveils unique stem cell partnership that can lead to advances in regenerative medicine

A study led by a researcher at Albert Einstein College of Medicine of Yeshiva University has revealed a unique "partnership" between two types of bone marrow stem cells, which could lead to advances in regenerative medicine. The aim of regenerative medicine is to enable the body to repair, replace, restore or regenerate damaged or diseased cells, tissues and organs.

18 Aug 2010

Researchers develop genetically mutated stem cells for myelin research

Vanishing White Matter (VWM) disease is a devastating condition that involves the destruction of brain myelin due to a mutation in a central factor. To understand the disease and test potential treatments that could apply to other disorders, such as multiple sclerosis, Prof. Orna Elroy-Stein of Tel Aviv University's Department of Cell Research and Immunology is leading a scientific breakthrough by developing laboratory mice which carry the VWM mutation an important new tool.

18 Aug 2010

Moderate wine consumption associated with better cognitive performance

A large prospective study of 5033 men and women in the Troms- Study in northern Norway has reported that moderate wine consumption is independently associated with better performance on cognitive tests. The subjects (average age 58 and free of stroke) were followed over 7 years during which they were tested with a range of cognitive function tests.

18 Aug 2010