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Calcium waves could be relevant for understanding the origin of Alzheimer's disease

New insights on what causes Alzheimer's disease could arise from a recent discovery made by bioengineers from the University of California, San Diego. The finding concerns the infamous amyloid beta peptides (Aβ)-fragments of which form plaques thought to play a role in Alzheimer's disease.

15 Feb 2010

Surgical outcomes for hip and knee replacement better at specialized hospitals

The more specialized a hospital is in orthopedic surgical care, the better the outcomes appear to be for patients undergoing hip and knee replacement surgery, University of Iowa researchers report in a new study of Medicare patients.

15 Feb 2010

Tobacco users with HPV-positive head and neck cancers at increased risk of recurrence

Patients with head and neck cancer linked to high risk human papillomavirus, or HPV, have worse outcomes if they are current or former tobacco users, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

15 Feb 2010

Study shows severe OSA suppresses cognitive experience of nightmare recall

A study in the Feb. 15 issue of the Journal of Clinical Sleep Medicine shows that patients with severe obstructive sleep apnea (OSA) report a significantly lower frequency of nightmares than patients with mild or no sleep apnea, indicating that OSA suppresses the cognitive experience of nightmare recall.

15 Feb 2010

Researchers use $1.3M grant from NIH to study on obesity and Type 2 diabetes

A team of Northern Arizona University-led researchers is using nearly $1.3 million in new funding from the National Institutes of Health to continue with the world's longest-running study on obesity and Type 2 diabetes.

15 Feb 2010

SRC-3 gene sends signal to cell membrane to promote cell motility

The master gene called SRC-3 (steroid receptor coactivator 3) not only enhances estrogen-dependent growth of cancer cells by activating and encouraging the transcription of a genetic message into a protein, it also sends a signal to the cell membrane to promote cell motility or movement - a key element of cancer spread or metastasis, said Baylor College of Medicine (www.bcm.edu) researchers and collaborators in a report that appears in the current issue of the journal Molecular Cell.

15 Feb 2010

Plagiocephaly babies need to be screened and monitored early in life for possible cognitive, motor delays

In a new study, infants averaging six months of age who exhibited positional plagiocephaly (flat head syndrome) had lower scores than typical infants in observational tests used to evaluate cognitive and motor development. Positional or deformational plagiocephaly may occur when external forces shape an infant's skull while it is still soft and malleable, such as extended time spent lying on a hard surface or in one position. This is the first controlled study to suggest that babies who have flattened areas on the back of their heads during the first year of life may be at risk for developmental delay.

15 Feb 2010

Air pollution linked to increased risk of atherosclerosis

Researchers at the Keck School of Medicine of the University of Southern California (USC), in collaboration with international partners in Spain and Switzerland and colleagues in California, have found that exposure to air pollution accelerates the thickening of artery walls that leads to cardiovascular disease.

15 Feb 2010

Chocolates may reduce risk of death after stroke

Giving chocolates to your Valentine on February 14th may help lower their risk of stroke based on a preliminary study from researchers at St. Michael's Hospital. The study, which is being presented at the American Academy of Neurology in April, also found that eating chocolate may lower the risk of death after suffering a stroke.

15 Feb 2010

Researchers discover Dab2 protein that switches on EMT process

Reporting in Nature Cell Biology, researchers describe the discovery of a specific protein called disabled-2 (Dab2) that switches on the process that releases cancer cells from the original tumor and allows the cells to spread and develop into new tumors in other parts of the body.

15 Feb 2010

Proteins found in intestines can recognize and kill bacteria that have human blood type molecules

A set of proteins found in our intestines can recognize and kill bacteria that have human blood type molecules on their surfaces, scientists at Emory University School of Medicine have discovered.

15 Feb 2010

Researcher receives $2.4M grant from NIH to study preeclampsia and diabetes in pregnant women

The link between obesity and high-risk pregnancies caused by preeclampsia and diabetes will be the focus of a $2.4 million National Institutes of Health research grant received by Sean Blackwell, M.D., associate professor in the Department of Obstetrics, Gynecology, and Reproductive Sciences at The University of Texas Medical School at Houston.

15 Feb 2010

Diabetic retinopathy: 5.3M U.S adults suffer

Despite major progress in diagnosis and treatment, diabetic retinopathy remains the major cause of blindness in adults under 60 in the U.S., said Thomas C. Lee, director, Retina Institute in The Vision Center at Childrens Hospital Los Angeles, associate professor of clinical ophthalmology at the Keck School of Medicine of the University of Southern California and attending physician at Doheny Eye Institute.

12 Feb 2010

New research finds sensory cortex develops late in fragile X syndrome defect

Why do people with fragile X syndrome, a genetic defect that is the best-known cause of autism and inherited mental retardation, recoil from hugs and physical touch - even from their parents?

12 Feb 2010

New project to unravel secret lives of cancer cells may help produce new cancer therapies

A team of scientists from Princeton University and The Cancer Institute of New Jersey has embarked on a major new project to unravel the secret lives of cancer cells that go dormant and self-cannibalize to survive periods of stress. The work may help produce new cancer therapies to stem changes that render cancer cells dangerous and resistant to treatment.

12 Feb 2010

Ethnic and racial minorities less likely to receive A1C diabetes test

Ethnic and racial minorities bear a disproportionate share of America's diabetes epidemic but are significantly less likely than whites to receive a commonly used test to monitor control of blood glucose, according to Washington State University researchers.

12 Feb 2010

Clinical research study conducted for patients with IC/PBS

A clinical research study is being conducted for patients with Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS), a chronic bladder disorder characterized by intense pelvic pain, urinary frequency-urgency, and pain during sexual intimacy (www.PainfulBladderStudy.org). It is estimated that as many as 1.3 million people in the U.S. have been diagnosed with this disease and many more remain undiagnosed.

12 Feb 2010

Study: Hospitalizations for H1N1 differ from hospitalizations associated with typical flu

When compared to a typical flu, the H1N1 virus resulted in a higher proportion of patients requiring specialized hospital services - and affected younger people more - according to a new study released today by the Canadian Institute for Health Information (CIHI).

12 Feb 2010

Sustamine L-Alanyl-L-Glutamine supplement increases performance in endurance exercise and activity

A clinical study by Dr. Jay Hoffman, PhD, professor and chair of the Department of Health and Exercise Science at the College of New Jersey, has shown Sustamine™ L-Alanyl-L-Glutamine, increases performance in endurance exercise and activity. The study was published on February 3, 2010, in the Journal of the International Society of Sports Nutrition (JISSN), a peer-reviewed journal covering various aspects of sports nutrition, supplementation, exercise metabolism, and/or scientific policies related to sports nutrition.

12 Feb 2010

3SBio, Ascentage Pharma announce cancer therapeutics collaboration

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, and Ascentage Pharma Group Corporation, Ltd. ("Ascentage Pharma") announced today that they have formed a strategic alliance to research, develop and commercialize best-in-class targeted cancer therapeutics focusing on programmed cell death, or apoptosis. The alliance will leverage Ascentage Pharma's expertise in structure-based small molecule design, lead optimization and preclinical development with 3SBio's proven drug development and commercialization capabilities in China.

12 Feb 2010

Medical Research News

Calcium waves could be relevant for understanding the origin of Alzheimer's disease

Surgical outcomes for hip and knee replacement better at specialized hospitals

Tobacco users with HPV-positive head and neck cancers at increased risk of recurrence

Study shows severe OSA suppresses cognitive experience of nightmare recall

Researchers use $1.3M grant from NIH to study on obesity and Type 2 diabetes

SRC-3 gene sends signal to cell membrane to promote cell motility

Plagiocephaly babies need to be screened and monitored early in life for possible cognitive, motor delays

Air pollution linked to increased risk of atherosclerosis

Chocolates may reduce risk of death after stroke

Researchers discover Dab2 protein that switches on EMT process

Proteins found in intestines can recognize and kill bacteria that have human blood type molecules

Researcher receives $2.4M grant from NIH to study preeclampsia and diabetes in pregnant women

Diabetic retinopathy: 5.3M U.S adults suffer

New research finds sensory cortex develops late in fragile X syndrome defect

New project to unravel secret lives of cancer cells may help produce new cancer therapies

Ethnic and racial minorities less likely to receive A1C diabetes test

Clinical research study conducted for patients with IC/PBS

Study: Hospitalizations for H1N1 differ from hospitalizations associated with typical flu

Sustamine L-Alanyl-L-Glutamine supplement increases performance in endurance exercise and activity

3SBio, Ascentage Pharma announce cancer therapeutics collaboration

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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