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Significant differences develop in obesity trends over time by race and ethnicity: Study

Obesity rates have started to decline and level off for many adolescents, but continue to increase for certain racial and ethnic minorities, according to a new UCSF-led study. The evidence of increasing racial disparities for obesity underscores the need for more tailored intervention programs and policies that target high-risk groups, the authors conclude.

16 Aug 2010

Scientists discover new signaling pathway to reduce tumour growth in glioblastoma multiforme

Malignant gliomas are the most common subtype of primary brain tumor - and one of the deadliest. Even as doctors make steady progress treating other types of solid tumor cancers, from breast to prostate, the most aggressive form of malignant glioma, called a glioblastoma multiforme or GBM, has steadfastly defied advances in neurosurgery, radiation therapy and various conventional or novel drugs. But an international team of scientists, headed by researchers at the Ludwig Institute for Cancer Research (LICR) at the University of California, San Diego School of Medicine, reports in the August 15 issue of Genes & Development that they have discovered a new signaling pathway between GBM cells - one that, if ultimately blocked or disrupted, could significantly slow or reduce tumor growth and malignancy.

16 Aug 2010

Low socioeconomic status, stressful childhood events develop risk of cardiovascular disease

Early life adversity through poverty, social isolation or abuse in childhood is linked to heightened reactivity, which can lead to heart disease later on, a leading expert on stress and disease said Saturday."Many diseases first diagnosed in mid-life can be traced back to childhood," Karen A. Matthews, PhD, said at the 118th Annual Convention of the American Psychological Association. "Having some bad health habits in your 20s and 30s is part of the reason why people get diseases later on. However, it isn't the whole reason. The evidence shows that certain reactions to adverse childhood experiences associated with lower socioeconomic status, isolation and negative events can affect the disease process."

16 Aug 2010

Study shows early diagnosis of atrial fibrillation reduces risk of stroke

The earlier that patients who suffer from atrial fibrillation obtain the correct treatment, the lower is the risk of serious secondary effects such as stroke. A thesis presented at the University of Gothenburg, Sweden, shows that a well-established measurement score can easily assess the risks for this patient group.

16 Aug 2010

Daily dose of aspirin may reduce prostate cancer risk: US Study

A US study has found that a daily dose of aspirin may reduce the risk of prostate cancer, but Cancer Research UK has noted that regular use of aspirin can cause serious side-effects and should not be undertaken unless recommended by a doctor.Several previous studies have looked at the possibility of an association between aspirin use and a reduced risk of prostate cancer.In the latest study, scientists at the Fred Hutchinson Cancer Research Centre in Seattle, led by Dr Janet Stanford, looked at data on 1,001 prostate cancer patients and a similar number of cancer-free volunteers.

16 Aug 2010

MeCP2 regulatory protein determines vulnerability to cocaine addiction: Research

A regulatory protein best known for its role in a rare genetic brain disorder also may play a critical role in cocaine addiction, according to a recent study in rats, funded by the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health. The study was published today in the journal Nature Neuroscience.

16 Aug 2010

Common genetic variation in HLA region associated with late-onset sporadic Parkinson's disease: Research

A team of researchers has discovered new evidence that Parkinson's disease may have an infectious or autoimmune origin. "Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease" appears online in Nature Genetics.

16 Aug 2010

CD31 positive cells have potential for treating peripheral artery disease: Research

Isolating cells from a patient's blood or bone marrow that nourish blood vessels may be a safer and less arduous route to treatment of cardiovascular disease than obtaining rare stem cells, according to research from Emory University School of Medicine. In recent clinical trials, doctors in several countries have tested the ability of a patient's bone marrow cells to repair damage, such as heart attacks and peripheral artery disease, created by problems of blood flow.

16 Aug 2010

Obesity linked to sleep disorders: Study

Specialists at a sleep clinic in Newcastle, Australia have analyzed 20 years of patient’s records and found that their patients are becoming increasingly obese. This means that the rise in obesity rates is directly related to rise in sleep problems they say.

16 Aug 2010

Obesity diabetes link found

Melbourne researchers from the Walter and Eliza Hall Institute have found that inflammatory cells in fat tissue cause the body to become resistant to the effects of insulin – a common precursor to type II diabetes.

16 Aug 2010

UCLA Professor receives 2010 Rumelhart Prize for research on AI

The Cognitive Science Society today announces that Professor Judea Pearl of University of California at Los Angeles has received the 2010 Rumelhart Prize for his leading research in Artificial Intelligence and systems that reason plausibly from uncertain evidence. His work on graphical models addresses one of the deepest challenges in philosophy and science: The dynamics of beliefs and the analysis of causality.

13 Aug 2010

CRF announces additional featured trials to be presented at Transcatheter Cardiovascular Therapeutics 2010

The Cardiovascular Research Foundation has announced that in addition to the previously announced late breaking clinical trials and first reports, a series of additional featured trials will be presented at the Transcatheter Cardiovascular Therapeutics (TCT) 2010 scientific symposium. These trials will focus on a wide range of significant topics in interventional cardiovascular medicine. TCT 2010 will take place September 21 - 25 in Washington, DC.

13 Aug 2010

University of Alberta and Health Canada announce study on Residential Indoor Air Quality

Researchers at the University of Alberta are trying to help clear the air about the levels of air pollutants in people's homes.

13 Aug 2010

Research reveals self-care improves healing experience

New research conducted by Experience In Motion LLC (EIM), Minneapolis, reveals that when healthcare organizations, their staff and practitioners engage in self-care as an organizational strategy, it not only improves the healing experience for themselves and patients, but it also improves business measures.

13 Aug 2010

Study identifies use of acetaminophen may increase asthma symptoms in adults

New evidence linking the use of acetaminophen to development of asthma and eczema suggests that even monthly use of the drug in adolescents may more than double risk of asthma in adolescents compared to those who used none at all; yearly use was associated with a 50 percent increase in the risk of asthma.

13 Aug 2010

NIEHS procures Provantis preclinical software solution for National Toxicology Program studies

Instem, a leading provider of early drug development software solutions, announced today that the National Institute of Environmental Health Sciences has purchased the Provantis® preclinical software solution to support the collection, management and maintenance of the reproductive, perinatal and developmental National Toxicology Program studies. These studies are done predominantly at contractor laboratories at various sites throughout the United States.

13 Aug 2010

A*STAR's Singapore Immunology Network, Institut M-rieux and bioM-rieux partner in TB research

An investment of S$3 million is being pumped into tuberculosis (TB) research by A*STAR's Singapore Immunology Network (SIgN), bioindustrial group Institut M-rieux and its in vitro diagnostics company bioM-rieux. The project, which involves setting up a joint laboratory in Biopolis, Singapore aims to investigate and identify novel biomarkers that could allow early identification of individuals at risk of TB disease development and disease reactivation. This could lead to better diagnosis and treatment for the highly contagious disease.

13 Aug 2010

Severe inflammatory response to initial UTI causes bladder damage: Research

The immune system may open the door to recurrent urinary tract infections (UTIs) by overdoing its response to an initial infection, researchers at Washington University School of Medicine in St. Louis have found.Researchers showed in mice that severe inflammatory responses to an initial UTI cause bladder damage and allow infection to persist longer. After one to two weeks of infection, the bladder wall undergoes additional changes that leave mice more vulnerable to later infection. Suppressing the immune system during initial infection decreases these vulnerabilities, they report Aug. 12 in PLoS Pathogens.

13 Aug 2010

Clearstone Central Laboratories announces strategic global collaboration with LabCorp

Clearstone Central Laboratories, a leading provider of central laboratory services for late-stage clinical trials, announced today a global collaboration with Laboratory Corporation of America® Holdings through its Esoterix Clinical Trials Services division, providing clients with seamless access to CAP-accredited laboratories across both organizations in Belgium, Canada, China, France, Singapore and the United States.

13 Aug 2010

Study examines impact of microvascular decompression surgery for type 2 diabetes

A team of Allegheny General Hospital (AGH) physicians led by neurosurgical pioneer Peter Jannetta, MD, has made an important new discovery linking the central nervous system to the onset and progression of type 2 diabetes mellitus.Reporting today in the journal Surgical Neurology International, Dr. Jannetta and his colleagues present evidence from a prospective clinical trial that vascular compression of a section of the brain called the medulla oblongata is a factor in some patients with type 2 diabetes and that microvascular decompression surgery (MVD) may be an effective treatment for the condition.

13 Aug 2010

Medical Research News

Significant differences develop in obesity trends over time by race and ethnicity: Study

Scientists discover new signaling pathway to reduce tumour growth in glioblastoma multiforme

Low socioeconomic status, stressful childhood events develop risk of cardiovascular disease

Study shows early diagnosis of atrial fibrillation reduces risk of stroke

Daily dose of aspirin may reduce prostate cancer risk: US Study

MeCP2 regulatory protein determines vulnerability to cocaine addiction: Research

Common genetic variation in HLA region associated with late-onset sporadic Parkinson's disease: Research

CD31 positive cells have potential for treating peripheral artery disease: Research

Obesity linked to sleep disorders: Study

Obesity diabetes link found

UCLA Professor receives 2010 Rumelhart Prize for research on AI

CRF announces additional featured trials to be presented at Transcatheter Cardiovascular Therapeutics 2010

University of Alberta and Health Canada announce study on Residential Indoor Air Quality

Research reveals self-care improves healing experience

Study identifies use of acetaminophen may increase asthma symptoms in adults

NIEHS procures Provantis preclinical software solution for National Toxicology Program studies

A*STAR's Singapore Immunology Network, Institut M-rieux and bioM-rieux partner in TB research

Severe inflammatory response to initial UTI causes bladder damage: Research

Clearstone Central Laboratories announces strategic global collaboration with LabCorp

Study examines impact of microvascular decompression surgery for type 2 diabetes

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