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SYNTAX defines borders between CABG and PCI with TAXUS drug-eluting stents

Coronary artery bypass grafting (CABG) should remain the "standard of care" for patients with complex coronary artery disease, concludes the SYNTAX study, published in the New England Journal of Medicine (online February 18, 2009, Print edition March 5).

23 Feb 2009

Scientists identify lab-made proteins that neutralize a broad range of influenza A viruses

Scientists have identified a small family of lab-made proteins that neutralize a broad range of influenza A viruses, including the H5N1 avian virus, the 1918 pandemic influenza virus and seasonal H1N1 flu viruses.

23 Feb 2009

Patient knowledge of health information influences cancer treatment

A new analysis finds that when colorectal cancer patients seek out health information from the internet and news media, they are more likely to be aware of and receive the latest treatments for their disease.

23 Feb 2009

Why we turn gray

A team of European scientists have finally solved a mystery that has perplexed humans throughout the ages: why we turn gray.

23 Feb 2009

New technique to determine tumor methylation status

Current research suggests that a new technique to determine tumor methylation status can be used in archived tissue samples.

23 Feb 2009

Mechanisms that prevent Alzheimer's Disease: Enzymatic activity plays key role

In a project involving the collaboration of several institutes, research scientists of the Johannes Gutenberg University Mainz have succeeded in gaining further insight in the functioning of endogenous mechanisms that protect against the development of Alzheimer's disease.

23 Feb 2009

Metastasis-promoting protein identified; could provide a prognostic test or target for breast cancer

Tumors that are about to progress and metastasize go through a process also seen in normal embryonic development, known as the epithelial to mesenchymal transition (EMT).

23 Feb 2009

Magnetic device studied as treatment for heartburn and acid reflux

More than 20 million Americans suffer from gastroesophageal reflux disease (GERD), experienced by many as chronic heartburn.

23 Feb 2009

Reminders may increase colon cancer screening

Mailed reminders to patients appear to promote colon cancer screening, according to a report in the February 23 issue of Archives of Internal Medicine.

23 Feb 2009

Researchers examine role of high cholesterol in prostate cancer

Current research suggests that lowering cholesterol may block the growth of prostate tumors.

23 Feb 2009

Human stem cells provide a new model for Lou Gehrig's disease

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a devastating condition in which motor neuron degeneration causes progressive loss of movement and muscle tone, leading to death.

23 Feb 2009

Discovery of gene that controls the production of tooth enamel

Researchers have identified the gene that ultimately controls the production of tooth enamel, a significant advance that could some day lead to the repair of damaged enamel, a new concept in cavity prevention, and restoration or even the production of replacement teeth.

23 Feb 2009

Enhanced skin cancer risk linked to defects in cellular aging controls

Cell lifespan is limited by telomeres, DNA sequences that cap chromosomes and control the number of times a cell may be copied.

23 Feb 2009

Statins may lessen brain function

Research by an Iowa State University scientist suggests that cholesterol-reducing drugs known as statins may lessen brain function.

23 Feb 2009

Researchers develop 'wireless' activation of brain circuits

Traditionally, stimulating nerves or brain tissue involves cumbersome wiring and a sharp metal electrode.

23 Feb 2009

Redesign technique for proteins

Proteins are widely viewed as a promising alternative to synthetic chemicals in everything from medications to hand lotion.

23 Feb 2009

New understanding of how anger can ventricular arrhythmias

New research published in the March 3, 2009, issue of the Journal of the American College of Cardiology finds that anger-induced electrical changes in the heart can predict future arrhythmias in patients with implantable cardioverter-defibrillators (ICDs).

23 Feb 2009

Aneurysms do not occur earlier in second generation

People whose parents or aunts and uncles have had a brain aneurysm are more likely to have one themselves, indicating that genetic risk factors passed down by generation are responsible.

23 Feb 2009

Gold nanoparticles improve gene regulation

Investigators at Northwestern University have found that packing small interfering RNA (siRNA) molecules onto the surface of a gold nanoparticle can protect siRNAs from degradation and increase their ability to regulate genes involved in cancer. As a result of this discovery, cancer researchers have at their disposal a relatively straightforward method of delivering these potent gene-regulating agents into targeted cells.

23 Feb 2009

Targeted nanospheres find, penetrate, then fuel burning of melanoma

Hollow gold nanospheres equipped with a targeting peptide find melanoma cells, penetrate them deeply, and then cook the tumor when bathed with near-infrared light. When heated with lasers, the actively targeted hollow gold nanospheres did eight times more damage to melanoma tumors in mice than did the same nanospheres that gathered less directly in the tumors.

23 Feb 2009