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NCI awards LSUHSC-NOLA Louisiana Tumor Registry $12 million SEER contract

The Louisiana Tumor Registry (LTR) at the LSU Health Sciences Center New Orleans School of Public Health has been awarded a $12 million contract over seven years by the National Cancer Institute to continue its work as a SEER (Surveillance, Epidemiology and End Results) Program-designated cancer registry. There are 18 competitively awarded SEER cancer registries in the United States.

3 Aug 2010

People insensitive to quinine's bitter taste may have varied absorption, metabolization capabilities: Study

Some people find quinine to be bitter while others can drink it like water. Now, scientists from the Monell Center and collaborators report that individual differences in how people experience quinine's bitterness are related to underlying differences in their genes.The findings, published online in the journal Human Molecular Genetics, demonstrate that genetic variation in regions of DNA that encode bitter taste receptors predicts a person's perception of bitterness from quinine.

3 Aug 2010

Biomaterials-based bone grafts can manipulate cell behavior to repair injury

Scientists have developed a material for bone grafts that could one day replace the 'gold standard' natural bone implants.A new study shows how particles of a ceramic called calcium phosphate have the ability to stimulate promising bone regrowth by attracting stem cells and 'growth factors' to promote healing and the integration of the grafted tissue.

3 Aug 2010

Placebo response in Parkinson's disease treatment varies with patient expectations

Individuals with Parkinson's disease were more likely to have a neurochemical response to a placebo medication if they were told they had higher odds of receiving an active drug, according to a report in the August issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

3 Aug 2010

Healthy heart may slow down aging of brain: Study

Keep your heart healthy and you may slow down the aging of your brain, according to a new study reported in Circulation: Journal of the American Heart Association.In the study, people whose hearts pumped less blood had brains that appeared older than the brains of those whose hearts pumped more blood. Decreased cardiac index, the amount of blood that pumps from the heart in relation to a person's body size, was associated with decreased brain volume using magnetic resonance imaging (MRI).

3 Aug 2010

Study explores role of genetic influence on ulcerative colitis

Adults diagnosed with ulcerative colitis after age 50 are more likely to achieve remission from their symptoms than patients diagnosed at younger ages, even when those patients receive similar treatments, according to research at Washington University School of Medicine in St. Louis.

3 Aug 2010

Environmental influences on college freshman weight gain

If college students gain weight during their first year in school, it might have a lot to do with how close they live to their campus dining halls and exercise facilities, a new study reports.

3 Aug 2010

Researchers discover manipulation of microRNA-29a shows potential of novel IBS treatment

A possible cause of irritable bowel syndrome has been traced to a small piece of RNA that blocks a substance protecting the colon membrane, leading to hostile conditions that can produce diarrhea, bloating and chronic abdominal pain.New research shows that this RNA segment sends signals that stop the activity of the gene that produces glutamine, an amino acid. Previous research has linked a shortage of glutamine in the gut with the seepage of toxins and bacteria through the intestinal wall, irritating nerves and creating disease symptoms.

3 Aug 2010

GG genotype may increase severity of multiple sclerosis symptoms: Study

A new study shows a gene variant may increase the severity of multiple sclerosis (MS) symptoms. The research will be published in the August 3, 2010, issue of Neurology, the medical journal of the American Academy of Neurology.For the study, researchers screened the oligoadenylate synthetase gene in 401 people with MS, 394 people without MS and 178 people receiving the MS treatment beta interferon.

3 Aug 2010

New fat cell with potentially harmful characteristics: Study

The new fat cells arise from stem cells in the bone marrow that travel through the blood stream to fat tissue. They are termed bone marrow progenitor-derived adipocytes. The discovery also revealed that male and female subjects accumulate the new fat cells differently. The research also may help to explain the link between types of obesity and heart disease and other illnesses.

3 Aug 2010

Alphavirus vector induce immune responses in people with advanced cancer: Researchers

There are several challenges to be overcome if therapeutic anticancer vaccines, which are designed to boost the patient's anticancer immune response, are to be successfully developed. For example, the viruses used to deliver the tumor protein to the patient's immune system are themselves targeted by the patient's immune system, inducing neutralizing and suppressive responses. But now, a team of researchers, led by Michael Morse, at Duke University Medical Center, Durham, has developed a way to overcome these neutralizing and suppressive responses by using an alphavirus packaged in virus-like replicon particles.

3 Aug 2010

Neuroglobin may protect against Alzheimer's disease: Study

A team of scientists at the University of California, Davis and the University of Auckland has discovered that neuroglobin may protect against Alzheimer's disease by preventing brain neurons from dying in response to natural stress. The team published the results of their study in the April, 2010 issue of Apoptosis.

3 Aug 2010

OECD approves new, non-animal testing guideline for skin irritation

After more than a decade of scientific research and lobbying by animal protection groups, the Organisation for Economic Cooperation and Development (OECD) has approved a new, non-animal testing guideline for skin irritation. The guideline was adopted on July 22 and it is now available for use by companies and governments worldwide.

3 Aug 2010

Research links body weight to glaucoma risk

This month's Ophthalmology journal includes surprising research from the Massachusetts Eye and Ear Infirmary on the relation of body weight to the risk for glaucoma. Also, from researchers at the Tokyo Medical and Dental University, comes the first specific map of how the development of myopic maculopathy, an illness that afflicts many severely nearsighted people, predicts which patients will be most susceptible to vision loss.

3 Aug 2010

Color red makes men more alluring to women: Study

It's a symbol of courage and sacrifice, of sin and sexuality, of power and passion - and now new research demonstrates that the color red makes men more alluring to women.In the United States, England, Germany and China, women found men more appealing when they were either pictured wearing red or framed in red, compared with other colors. The finding is reported in the August issue of the Journal of Experimental Psychology: General, published by the American Psychological Association.

3 Aug 2010

Disparities in cardiovascular disease risk linked to socioeconomic differences between races: Study

A new UCLA study suggests that disparities in cardiovascular disease risk in the United States are due less to race or ethnicity than to socioeconomic status.

2 Aug 2010

Research findings could lead to new drugs that reduce severity of blood infections leading to sepsis

Scientists have made an important discovery that could lead to new drugs that reduce the severity of blood infections leading to sepsis. Research presented in the August 2010 issue of Journal of Leukocyte Biology shows how interfering with the function of the cell membrane protein called "Programmed Death 1" (PD-1) improves survival in a clinically relevant model of severe infection.

2 Aug 2010

Thymosin beta 4 is essential to healthy heart development, embryonic survival: Research

RegeneRx Biopharmaceuticals, Inc. today announced that a research team from the Molecular Medicine Unit at UCL-Institute of Child Health in London reported preclinical findings that Thymosin beta 4, is essential to healthy heart development and embryonic survival.

2 Aug 2010

HDL does not predict heart attack risk after dramatic statin therapy: Study

People with high levels of "good cholesterol," HDL-C, tend to have fewer heart attacks, but HDL-C may offer little protection to people who take statins to lower harmful LDL cholesterol, researchers reported July 21. At Brigham and Women's Hospital in Boston, Dr. Paul Ridker and colleagues analyzed a large study of healthy people who took the statin CRESTOR® (rosuvastatin calcium) to prevent heart attacks. They found that in this group, having high HDL-C was a bad predictor of heart attack risk.

2 Aug 2010

DAIICHI SANKYO EUROPE adopts DATATRAK's eClinical platform for cardiovascular clinical study

DATATRAK International, Inc., a technology and services company focused on global eClinical solutions for the clinical trials industry, today announced that DAIICHI SANKYO EUROPE GmbH has selected DATATRAK's eClinical™ platform for a cardiovascular clinical study encompassing 80 sites and 1,200 patients across Europe.

2 Aug 2010

Medical Research News

NCI awards LSUHSC-NOLA Louisiana Tumor Registry $12 million SEER contract

People insensitive to quinine's bitter taste may have varied absorption, metabolization capabilities: Study

Biomaterials-based bone grafts can manipulate cell behavior to repair injury

Placebo response in Parkinson's disease treatment varies with patient expectations

Healthy heart may slow down aging of brain: Study

Study explores role of genetic influence on ulcerative colitis

Environmental influences on college freshman weight gain

Researchers discover manipulation of microRNA-29a shows potential of novel IBS treatment

GG genotype may increase severity of multiple sclerosis symptoms: Study

New fat cell with potentially harmful characteristics: Study

Alphavirus vector induce immune responses in people with advanced cancer: Researchers

Neuroglobin may protect against Alzheimer's disease: Study

OECD approves new, non-animal testing guideline for skin irritation

Research links body weight to glaucoma risk

Color red makes men more alluring to women: Study

Disparities in cardiovascular disease risk linked to socioeconomic differences between races: Study

Research findings could lead to new drugs that reduce severity of blood infections leading to sepsis

Thymosin beta 4 is essential to healthy heart development, embryonic survival: Research

HDL does not predict heart attack risk after dramatic statin therapy: Study

DAIICHI SANKYO EUROPE adopts DATATRAK's eClinical platform for cardiovascular clinical study

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