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Mothers and offspring can share cells throughout life - with positive and negative effects

Cutting the umbilical cord doesn't necessarily sever the physical link between mother and child. Many cells pass back and forth between the mother and fetus during pregnancy and can be detected in the tissues and organs of both even decades later. This mixing of cells from two genetically distinct individuals is called microchimerism. The phenomenon is the focus of an increasing number of scientists who wonder what role these cells play in the body.

30 Apr 2008

Discovery of quick method for making human monoclonal antibodies against flu

Human monoclonal antibodies (mAbs) - highly specific, identical, infection-fighting proteins produced in large quantities in the lab in cell lines that are derived from a single antibody-producing cell - against influenza can be rapidly produced in the lab, according to a new report from scientists supported by the National Institutes of Health (NIH).

30 Apr 2008

Yale scientists explain metastasis

Metastasis, the spread of cancer throughout the body, can be explained by the fusion of a cancer cell with a white blood cell in the original tumor, according to Yale School of Medicine researchers, who say that this single event can set the stage for cancer's migration to other parts of the body.

29 Apr 2008

Review of cervical cancer screening program shows effectiveness and room for improvement

Women who do not undergo regular cervical cancer screening tests are more likely to be diagnosed with the disease than those who do, according to an audit of the Swedish national cervical cancer screening program that will be published online April 29 in the Journal of the National Cancer Institute.

29 Apr 2008

Hydrogen sulphide may be involved in regulating blood pressure

Hydrogen sulphide is a gas most commonly associated with the smell of stink bombs, sewage and rotten eggs, but a team of researchers from the Peninsula Medical School in the South West of England and King's College London have now identified a role for this gas in regulating blood pressure, according to research published in the leading science journal "Circulation".

29 Apr 2008

Aspirin-like compounds (salicylates) increase insulin secretion in otherwise healthy obese people

Aspirin-like compounds (salicylates) can claim another health benefit: increasing the amount of insulin produced by otherwise healthy obese people. Obesity is associated with insulin resistance, the first step toward type 2 diabetes.

29 Apr 2008

Biomarkers identified for idiopathic pulmonary fibrosis

The first evidence of a distinctive protein signature that could help to transform the diagnosis and improve the monitoring of the devastating lung disease idiopathic pulmonary fibrosis (IPF) is being reported by University of Pittsburgh School of Medicine researchers in this month's edition of PLoS Medicine, an open-access journal of the Public Library of Science.

28 Apr 2008

African Americans have five times higher rate of lower limb amputations

The overall amputation rate in northern Illinois is declining due to improved care for diabetes and peripheral vascular disease, new research shows.

28 Apr 2008

Abmormal behaviour of osteoglycin gene linked to heart and kidney problems

A gene that can cause the heart to become enlarged, greatly increasing the risk of heart attacks and heart failure, is identified today in a new study.

28 Apr 2008

New drug discovery tool for Alzheimer's disease

An article published in the April issue of the Journal of Alzheimer's Disease presents a detailed characterization of a new drug discovery tool for Alzheimer's disease.

28 Apr 2008

Tissue-specific blood stem cell line established from embryonic stem cells

A research team at the Umea Center for Molecular Medicine (UCMM) in Sweden, led by Professor Leif Carlsson, has managed to specifically establish and isolate the tissue-specific stem cell that produces blood cells (blood stem cell) by using genetically modified embryonic stem cells.

28 Apr 2008

Scientists discover way to increase metabolism for weight loss

Scientists from Melbourne's Howard Florey Institute have discovered a way to aid weight loss and reduce the likelihood of developing diabetes by manipulating fat cells to increase the body's metabolism.

28 Apr 2008

Scientists explore brain's reaction to potent hallucinogen

Brain-imaging studies performed in animals at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory provide researchers with clues about why an increasingly popular recreational drug that causes hallucinations and motor-function impairment in humans is abused.

28 Apr 2008

Smokers more prone to depression

Researchers in Spain suggest that smokers are significantly more at risk of suffering depression than non-smokers.

28 Apr 2008

Research links low-frequency hearing to shape of the cochlea

Shape matters, even in hearing. Specifically, it is the shape of the cochlea - the snail-shell-shaped organ in the inner ear that converts sound waves into nerve impulses that the brain deciphers - which proves to be surprisingly important.

27 Apr 2008

Scientists discover 4th major set of common genetic variants linked to risk of estrogen receptor-positive breast cancer

Scientists from deCODE genetics report the discovery of two common single-letter variants (SNPs) on chromosome 5 of the human genome that are associated with risk of estrogen receptor-positive (ER+) breast cancer.

27 Apr 2008

Gene therapy restores vision in patients with rare congenital blindness

In a clinical trial at The Children's Hospital of Philadelphia, researchers from The University of Pennsylvania have used gene therapy to safely restore vision in three young adults with a rare form of congenital blindness.

27 Apr 2008

3D view of neurons provided by new technique

A new technique that marries a fast-moving laser beam with a special microscope that look at tissues in different optical planes will enable scientists to get a three-dimensional view of neurons or nerve cells as they interact, said Baylor College of Medicine scientists in a report that appears in the journal Nature Neuroscience.

27 Apr 2008

Different processes govern sight, light detection

A Johns Hopkins University biologist, in research with implications for people suffering from seasonal affective disorder and insomnia, has determined that the eye uses light to reset the biological clock through a mechanism separate from the ability to see.

27 Apr 2008