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MicroRNA undermines tumor suppression

Scientists at the Whitehead Institute for Biomedical Research and the National University of Singapore have discovered the first microRNA (miRNA) capable of directly tamping down the activity of the well known tumor-suppressor gene, p53, While p53 functions to prevent tumor formation, the p53 gene is thought to malfunction in more than 50% of cancerous tumors.

17 Mar 2009

Alzheimer's mechanism suggests combination therapy needed

Researchers at the University of Illinois at Chicago College of Medicine have discovered a mode of action for mysterious but diagnostic protein snarls found in the brains of Alzheimer's patients that suggests a one-two punch of therapy may be needed to combat the neurodegenerative disease.

17 Mar 2009

Lung cancer: Molecular scissors determine therapy effectiveness

In the past few years, a number of anti-cancer drugs have been developed which are directed selectively against specific key molecules of tumor cells.

17 Mar 2009

Link between religious coping and aggressive treatment in terminally ill cancer patients

In a new study of terminally ill cancer patients, researchers at Dana-Farber Cancer Institute found that those who draw on religion to cope with their illness are more likely to receive intensive, life-prolonging medical care as death approaches –– treatment that often entails a lower quality of life in patients' final days.

17 Mar 2009

HPV vaccine may prevent preterm births

Chronic human papilloma virus (HPV)-infections can lead to cellular changes in the cervix that can be a pre-stage to cervical cancer.

17 Mar 2009

Frankincense oil may be an inexpensive alternative therapy for bladder cancer

Originating from Africa, India, and the Middle East, frankincense oil has been found to have many medicinal benefits.

17 Mar 2009

Emotions and emotional control in eating disorders: predictor role and emotional profiles

A Ph.D. thesis at the University of the Basque Country has analyzed the role played by a number of emotional variables, such as the way in which negative emotions are controlled or attitudes to emotional expression, and to use these variables as tools to predict the possibility of suffering an eating disorder.

17 Mar 2009

Drug being used to improve cognition affects dopamine, suggesting potential for abuse

Preliminary research in healthy men suggests that the narcolepsy drug modafinil, increasingly being used to enhance cognitive abilities, affects the activity of dopamine in the brain in a way that may create the potential for abuse and dependence, according to a study in the March 18 issue of JAMA.

17 Mar 2009

Call for more thyroid function tests for older patients to improve diagnosis rate

A new study of over 3500 patients with overactive thyroids shows that elderly patients experience fewer signs and symptoms of the condition.

17 Mar 2009

BioNanomatrix awarded phase II NIH grant to support development of single-molecule nanoscale whole genome analyzer

BioNanomatrix, Inc. has announced receipt of a Phase II grant from the National Human Genome Research Institute (NHGRI) of the U.S. National Institutes of Health (NIH).

17 Mar 2009

Discovery of new mechanism for the processing of endocannabinoids

New research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, has identified a new mechanism for the processing of endocannabinoids, natural brain compounds similar to THC, the active ingredient in marijuana.

17 Mar 2009

Aspirin decreases first heart attacks in men and first strokes in women

Patients and clinicians should consider risk factors -- including age, gender, diabetes, blood pressure, cholesterol levels, smoking and risk of gastrointestinal bleeding -- before deciding whether to use aspirin to prevent heart attacks or strokes, according to new recommendations from the U.S. Preventive Services Task Force.

16 Mar 2009

Stun guns can cause brain-specific complications such as seizures

Stun guns, in certain circumstances, may result in brain-specific complications such as seizures, according to a new case report published in CMAJ http://www.cmaj.ca/press/pg625.pdf.

16 Mar 2009

Study finds that dying patients and families suffer from lack of continuity of physician care

In a study published in the March 9 issue of Archives of Internal Medicine, researchers found that patients and families can suffer from feelings of abandonment when a physician who had been actively involved in care is no longer involved.

16 Mar 2009

Diabetes cure in mice - answer is adult stem cells

More than five years ago, Dr. Lawrence C.B. Chan and colleagues in his Baylor College of Medicine laboratory cured mice with type 1 diabetes by using a gene to induce liver cells to make insulin.

16 Mar 2009

Shrinking in hippocampus area of brain precedes Alzheimer's disease

People who have lost brain cells in the hippocampus area of the brain are more likely to develop dementia, according to a study published in the March 17, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology.

16 Mar 2009

Search for blood pressure secrets reveals a surprising new syndrome

Yale researchers investigating the genetic causes of blood pressure variation have identified a previously undescribed syndrome associated with seizures, a lack of coordination, developmental delay and hearing loss.

16 Mar 2009

Scientists 'watch' as individual alpha-synuclein proteins change shape

In an Early Edition publication of The Proceedings of the National Academy of Sciences (PNAS) this week, the researchers demonstrate the "alpha-synuclein dance" - the switching back and forth of the protein between a bent helix and an extended helix as the surface that it is binding to changes.

16 Mar 2009

Risks of using aspirin to prevent heart attack or stroke differ by gender and age

Patients and clinicians should consider risk factors-- including age, gender, diabetes, blood pressure, cholesterol levels, smoking and risk of gastrointestinal bleeding-- before deciding whether to use aspirin to prevent heart attacks or strokes, according to new recommendations from the U.S. Preventive Services Task Force.

16 Mar 2009

Set of criteria help identify candidates for combined heart and kidney transplants

Researchers have identified a set of criteria that, when combined with a measure of kidney function, could help identify patients who are likely to receive a survival benefit from a combined heart and kidney transplant, according to a report in the March issue of Archives of Surgery.

16 Mar 2009

Medical Research News

MicroRNA undermines tumor suppression

Alzheimer's mechanism suggests combination therapy needed

Lung cancer: Molecular scissors determine therapy effectiveness

Link between religious coping and aggressive treatment in terminally ill cancer patients

HPV vaccine may prevent preterm births

Frankincense oil may be an inexpensive alternative therapy for bladder cancer

Emotions and emotional control in eating disorders: predictor role and emotional profiles

Drug being used to improve cognition affects dopamine, suggesting potential for abuse

Call for more thyroid function tests for older patients to improve diagnosis rate

BioNanomatrix awarded phase II NIH grant to support development of single-molecule nanoscale whole genome analyzer

Discovery of new mechanism for the processing of endocannabinoids

Aspirin decreases first heart attacks in men and first strokes in women

Stun guns can cause brain-specific complications such as seizures

Study finds that dying patients and families suffer from lack of continuity of physician care

Diabetes cure in mice - answer is adult stem cells

Shrinking in hippocampus area of brain precedes Alzheimer's disease

Search for blood pressure secrets reveals a surprising new syndrome

Scientists 'watch' as individual alpha-synuclein proteins change shape

Risks of using aspirin to prevent heart attack or stroke differ by gender and age

Set of criteria help identify candidates for combined heart and kidney transplants

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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