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New mouse model grants insight into the genetic and molecular mechanisms underpinning acute myeloid leukemia

Leukaemia - cancer of blood or bone marrow is caused by mutations that allow defective blood cells to accumulate and displace healthy blood.

8 Apr 2008

Leaky blood vessels open up nerve cells to toxic assault In Lou Gehrig's disease

Leaky blood vessels that lose their ability to protect the spinal cord from toxins may play a role in the development of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, according to research published in the April issue of Nature Neuroscience.

7 Apr 2008

Tart cherries cut heart/diabetes risk factors

Tart cherries - frequently sold dried, frozen or in juice - may have more than just good taste and bright red color going for them, according to new animal research from the University of Michigan Cardiovascular Center.

7 Apr 2008

Rare genetic variants have big impact on blood pressure

Yale University researchers report in the journal Nature Genetics that they have discovered that rare genetic variants can be associated with a dramatically lower risk of developing high blood pressure in the general population.

7 Apr 2008

T-cadherin affects blood vessel growth in breast cancer, hormone from fat cells may play a role

Researchers at the Burnham Institute for Medical Research (Burnham) may have found a new option for targeted breast cancer therapy by showing the link between a certain protein and the formation and development of blood vessels that feed breast tumors.

7 Apr 2008

Synthetic molecules may be less expensive alternative to therapeutic antibodies

Researchers at UT Southwestern Medical Center have developed a simple and inexpensive method to screen small synthetic molecules and pull out a handful that might treat cancer and other diseases less expensively than current methods.

7 Apr 2008

Salivary diagnostics

Accuracy, convenience, and non-invasiveness are the most critical characteristics for any diagnostic tool.

7 Apr 2008

Roswell Park Cancer Institute awarded three-years funding for ovarian cancer vaccine

The Ovarian Cancer Research Fund has awarded a $900,000 research grant to Kunle Odunsi, MD, Department of Gynecologic Oncology, and his colleagues at Roswell Park Cancer Institute (RPCI) to collaborate on developing a promising vaccine to unleash the power of the immune system against cancer.

7 Apr 2008

New research in monkeys may lead to new strategy for treating cocaine addiction

New research in monkeys suggests the feasibility of treating cocaine addiction with a "replacement" drug that mimics the effects of cocaine but has less potential for abuse - similar to the way nicotine and heroin addictions are treated.

7 Apr 2008

Rare mutations in salt handling genes protect against hypertension

Howard Hughes Medical Institute (HHMI) researchers have found that rare mutations in three genes contribute to blood pressure variation in the general population.

7 Apr 2008

NYU dental professor discovers biological clock linking tooth growth to other metabolic processes

This clock, or biological rhythm, controls many metabolic functions and is based on the circadian rhythm, which is a roughly 24-hour cycle that is important in determining sleeping and feeding patterns, cell regeneration, and other biological processes in mammals.

7 Apr 2008

Cancer treatment from a common avian virus under study

Researchers on the Blacksburg and College Park, Maryland campuses of the Virginia-Maryland Regional College of Veterinary Medicine have been awarded a major new grant from the National Institutes of Health (NIH) to support innovative work that seeks to develop a treatment for cancer from a common avian virus.

7 Apr 2008

Australian research tackles brain cancer, stroke

New studies at the University of Adelaide, Australia, will delve into some of the crucial issues surrounding death by brain tumours and stroke.

7 Apr 2008

Common molecule tRNA involved in building protein can trigger cancer

Cancer Research UK scientists have discovered that a common molecule previously known to play a fundamental role in building protein, can also trigger cancer.

7 Apr 2008

Periodontitis and human papillomavirus combined increase risk for tongue cancer

Persons with periodontitis who also are infected with human papillomavirus (HPV) are at increased risk of developing tongue cancer, new research conducted at the University at Buffalo School of Dental Medicine has shown.

7 Apr 2008

New blood test gives early diagnosis of neurodegenerative diseases

A new blood test that can give an early diagnosis of neurodegenerative disease and distinguish between Parkinson's and Alzheimer's disease could be launched this summer, reports Marina Murphy in SCI's Chemistry & Industry magazine.

7 Apr 2008

Fetal cells transplanted into the brain to treat Parkinson's may not function long term

Neurons grafted into the brain of a patient with Parkinson's disease fourteen years ago have developed Lewy body pathology, the defining pathology for the disease, according to research by Jeffrey H. Kordower, PhD, and associates and published in the April 6 issue of Nature Medicine.

7 Apr 2008