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Researchers reveal surface protein alteration mechanism of mycoplasma bacteria

Pathogenic bacteria have evolved a variety of mechanisms to avoid being killed by the immune systems of the humans and animals they invade. Among the most sophisticated is that practised by mycoplasmas, which regularly change their surface proteins to confuse the immune system. Recent work in the group of Renate Rosengarten and Rohini Chopra-Dewasthaly at the University of Veterinary Medicine, Vienna has revealed surprising new details of the way they do so and at the same time raised important evolutionary questions.

9 Sep 2010

Micro-RNAs programmed cells can lead to malignant growth

Cancer becomes life threatening when tumor cells start leaving their primary site. They travel through the lymph and blood streams to other tissues where they grow into metastases. This transition to malignancy is associated with characteristic changes in the cancer cells. The activity of several genes is reprogrammed and, thus, the production of proteins anchoring cells to a tissue is reduced. On the other hand, the amount of surface markers which make a cancer cell mobile increases.

9 Sep 2010

Researchers discover low levels of DHA associated with chronic neurodegenerative disease

UC Irvine researchers have discovered that markedly depleted amounts of an omega-3 fatty acid in brain tissue samples from Alzheimer's patients may be due to the liver's inability to produce the complex fat, also contained in fish-oil supplements.Low levels of docosahexaenoic acid, or DHA, have been associated with the chronic neurodegenerative disease affecting millions of Americans, but no cause had been identified.

9 Sep 2010

Scientists discover natural mechanism to discard amyloid protein

Chemists at the University of California, San Diego, have identified how a protein that accumulates in the brains of people with Alzheimer's disease interferes with the ability of cells to get rid of debris. They also found a natural mechanism by which this protein, amyloid beta, itself may be discarded.

9 Sep 2010

Federal judge refuses to lift order blocking federal funding for stem cell research

The Associated Press: "A federal judge on Tuesday refused to lift his order blocking federal funding for some stem cell research, saying that a 'parade of horribles' predicted by federal officials would not happen. Medical researchers value stem cells because they are master cells that can turn into any tissue of the body.

9 Sep 2010

Irregular body weight increases mortality risk in women with colon cancer: Study

Postmenopausal women diagnosed with colon cancer may be at increased risk of death if they fail to maintain a healthy body weight before cancer diagnosis, according to a study published in the September issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

9 Sep 2010

Researchers synthesize new compounds to reduce A-beta 42 peptide in Alzheimer's disease

A team of scientists, led by University of California, San Diego School of Medicine researchers, has synthesized hundreds of new compounds with the potential of reducing the production of the A-beta 42 peptide, a primary component of Alzheimer's disease (AD).

9 Sep 2010

Ohio State University receives five-year grant to improve drug therapy using gene profiles

The National Institute of General Medical Sciences has awarded a $9.1 million, five-year grant to The Ohio State University for a study titled "Expression Genetics in Drug Therapy." The goal of the research is to enhance drug response rates and reduce the number of adverse drug reactions among patients taking medication.

9 Sep 2010

Neck manipulation may be risky without significant benefits: Study

According to new research manipulation for neck pain may carry a risk of serious injury, including stroke. For the study more than 120 patients with neck pain were included. They were randomly assigned to be treated with either manipulation or mobilization - which involves small, rhythmic movements applied to stiff or inflamed tissue. The outcome of both groups was almost identical, prompting researchers to conclude that manipulation may not be worth the risk.

8 Sep 2010

NEXUS Biosystems acquires REMP from Tecan Group

NEXUS Biosystems, Inc., a leading innovator and worldwide provider of automated sample management systems, today announced the completion of the acquisition of REMP AG of Switzerland, a wholly-owned subsidiary of the Tecan Group.

From Tecan 8 Sep 2010

Vela Laboratories renews GMP certificate for analytical and Quality Control laboratories

Vela Laboratories, a provider of analytical services to the global biopharmaceutical industry, today announced the renewal of the GMP certificate for its analytical and Quality Control laboratories until 2013.

8 Sep 2010

Trius Therapeutics announces presentations from drug development programs at 50th ICAAC

Trius Therapeutics, Inc. announced today that the results of multiple studies from its drug development programs, including its lead antibiotic drug candidate torezolid phosphate (TR-701), will be presented in poster presentations at the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) meeting in Boston September 12-15.

8 Sep 2010

People in low-income areas experience more penetrating injuries than those in high-income regions: Study

Penetrating injury rates were more than 20 times higher for persons living in the lowest income neighborhoods compared with those living in the highest income neighborhoods, according to a new study published in the August issue of the Journal of the American College of Surgeons. Researchers also found that those in the lowest-income neighborhoods experienced nearly six times higher rates of blunt injury than persons in the highest income neighborhoods. Penetrating injuries included those from firearms or cuts; blunt injuries included motor vehicle crashes, falls and assaults.

8 Sep 2010

PPD establishes preferred provider relationships for conducting Phase I trials

PPD, Inc. today announced it has established preferred provider relationships with a network of sites across North America for conducting Phase I trials in patients to meet growing client demand for these services.

8 Sep 2010

Researchers to study suicide prevention program in high schools

With students returning to classes, University of Rochester Medical Center researchers are beginning a large, long-term study of the effectiveness of a unique suicide prevention program in high schools across New York and North Dakota.

8 Sep 2010

Risk factors for indoor and outdoor falls for elderly adults are different: Study

The risk factors for indoor and outdoor falls for older adults are different, according to a new study by the Institute for Aging Research of Hebrew SeniorLife, an affiliate of Harvard Medical School, a fact that is often missed when the two are combined and may affect how falls prevention programs are structured.

8 Sep 2010

NIH announces $161.3 million for expansion of Pharmacogenomics Research Network

The National Institutes of Health plans to spend $161.3 million over the next five years to expand the Pharmacogenomics Research Network (PGRN), a nationwide collaborative of scientists focused on understanding how genes affect a person's response to medicines.

8 Sep 2010

Researchers find blebbistatin chemically inhibits NMII, enhances survival of stem cells

Human pluripotent stem (hPS) cells can generate any given cell type in the adult human body, which is why they are of interest to stem cell scientists working on finding therapies for spinal cord injuries, Parkinson's disease, burns, heart disease, diabetes, arthritis, and other ailments.

8 Sep 2010

ECNP honors Kaj Blennow with 2010 Neuropsychopharmacology Award

The European College of Neuropsychopharmacology (ECNP) is pleased to announce Kaj Blennow as the recipient of the 2010 ECNP Neuropsychopharmacology Award in recognition of his original and influential contributions to Alzheimer's disease research. The ECNP Neuropsychopharmacology Award is presented annually and recognises distinguished research in neuropsychopharmacology and closely related disciplines. The award is accompanied by a prize of - 20,000.

8 Sep 2010

NIH announces $15 million for expansion of Pharmacogenomics Knowledge Base

To help advance research on how genes affect responses to medicines, the National Institutes of Health is spending $15 million over five years to expand a key resource, the Pharmacogenomics Knowledge Base (PharmGKB), http://www.pharmgkb.org/ .

8 Sep 2010

Medical Research News

Researchers reveal surface protein alteration mechanism of mycoplasma bacteria

Micro-RNAs programmed cells can lead to malignant growth

Researchers discover low levels of DHA associated with chronic neurodegenerative disease

Scientists discover natural mechanism to discard amyloid protein

Federal judge refuses to lift order blocking federal funding for stem cell research

Irregular body weight increases mortality risk in women with colon cancer: Study

Researchers synthesize new compounds to reduce A-beta 42 peptide in Alzheimer's disease

Ohio State University receives five-year grant to improve drug therapy using gene profiles

Neck manipulation may be risky without significant benefits: Study

NEXUS Biosystems acquires REMP from Tecan Group

Vela Laboratories renews GMP certificate for analytical and Quality Control laboratories

Trius Therapeutics announces presentations from drug development programs at 50th ICAAC

People in low-income areas experience more penetrating injuries than those in high-income regions: Study

PPD establishes preferred provider relationships for conducting Phase I trials

Researchers to study suicide prevention program in high schools

Risk factors for indoor and outdoor falls for elderly adults are different: Study

NIH announces $161.3 million for expansion of Pharmacogenomics Research Network

Researchers find blebbistatin chemically inhibits NMII, enhances survival of stem cells

ECNP honors Kaj Blennow with 2010 Neuropsychopharmacology Award

NIH announces $15 million for expansion of Pharmacogenomics Knowledge Base

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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