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New method improves immunotherapy

A study published by Elsevier this month in Clinical Immunology, the official journal of the Clinical Immunology Society (CIS), describes a new method that facilitates the induction of a specific type of immune suppressive cells, called 'regulatory T cells' for therapeutic use.

1 Dec 2008

Seniors with depression more likely to gain abdominal fat

Older adults with symptoms of depression appear more likely to gain abdominal fat, but not overall fat, over a five-year period, according to a report in the December issue of Archives of General Psychiatry.

1 Dec 2008

Patient harm more common with patient-controlled pain medication

Intravenous patient-controlled analgesia (PCA) allows patients to control their own pain medication, but a new study published in the December 2008 issue of The Joint Commission Journal on Quality and Patient Safety shows that errors related to this practice are four times more likely to result in patient harm than errors that occur with other medications.

1 Dec 2008

Poor quality HDL cholesterol bad for you

If you think your levels of "good cholesterol" are good enough, a new study published in the December 2008 issue of The FASEB Journal suggests that you may want to think again.

1 Dec 2008

Reprogrammable cell type depends on a single gene to keep its identity

Scientists at St. Jude Children's Research Hospital have discovered that a certain differentiated cell type is so ready to change its identity that it requires the constant expression of a gene called Prox1 to dissuade it.

1 Dec 2008

Place of birth plays a role in the occurrence of asthma in U.S black population

The researchers found that within one inner-city population, blacks born in the United States were more likely to have asthma than blacks who were born outside of the United States.

1 Dec 2008

Prostate cancer tumors promote nerve growth

Prostate cancer - and perhaps other cancers - promotes the growth of new nerves and the branching axons that carry their messages, a finding associated with more aggressive tumors, said researchers from Baylor College of Medicine in the first report of the phenomenon that appears today in the journal Clinical Cancer Research.

1 Dec 2008

Chemical used in antifouling paints may promote obesity

Tributyltin, a ubiquitous pollutant that has a potent effect on gene activity, could be promoting obesity, according to an article in the December issue of BioScience.

1 Dec 2008

Analysis of tissue biomarkers expressed in ovarian cancer samples

Although ovarian cancer is not the most common gynecologic cancer in women, the disease contributes a substantial burden of mortality in part because symptoms are nonspecific and the disease presents late in its course.

1 Dec 2008

Breakthrough in strategy used to develop new pharmacological treatments for schizophrenia

In one of the first instances of targeted drug design in psychiatric treatment, University of Pittsburgh researchers have found an experimental agent that shows promise in addressing working memory impairments that occur in schizophrenia.

1 Dec 2008

Magnetic imaging devices may damage cochlear implants

Patients with cochlear implants may want to steer clear of certain magnetic imaging devices, such as 3T MRI machines, because the machines can demagnetize the patient's implant, according to new research published in the December 2008 issue of Otolaryngology - Head and Neck Surgery.

1 Dec 2008

People with lower IQs may have greater risk of mental disorders

Researchers have hypothesized that people with lower IQs may have a higher risk of adult mental disorders, but few studies have looked at the relationship between low childhood IQ and psychiatric disorders later in life.

1 Dec 2008

Cardiac CT effectively assesses coronary artery stenosis

Cardiac CT can effectively assess coronary artery stenosis, according to a large study performed at Leiden University Medical Center in Leiden, The Netherlands.

1 Dec 2008

Vitamin D deficiency could lead to heart problems

Vitamin D deficiency - which is traditionally associated with bone and muscle weakness - may also increase the risk of cardiovascular disease (CVD).

1 Dec 2008

New insight into adhesion and migration of dendritic cells could lead to novel cancer treatments

Our immune system plays an essential role in protecting us from diseases, but how does it do this exactly?

1 Dec 2008

Protein indoleamine 2,3-dioxygenase points to new pancreatic cancer therapies

An enzyme that is overexpressed in pancreatic cancer cells may hold the key to successfully treating the disease with targeted immunotherapy, researchers from Thomas Jefferson University reported at the 2008 Annual Meeting of the Southern Surgical Association.

1 Dec 2008