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UT Southwestern regrets VA's unilateral decision to not renew the Gulf War research contract

We regret the VA's unilateral decision to not renew the contract supporting vital research focused on veterans suffering from Gulf War syndrome being carried out by UT Southwestern investigators and their collaborators elsewhere.

27 Aug 2009

Study suspects involvement of PPAR-γ in gastric carcinogenesis

Recently, the potential of PPAR-γ as a target for the prevention and treatment of cancer has been widely studied. However, the potential therapeutic role of PPAR-γ agonists has been questioned, based on contradictory results. Studies using animal models of colon cancer found that PPAR-γ agonists increased the development of colon tumors.

27 Aug 2009

Study confirms inappropriate use of pain medication among the chronic pain population

A study published in the August issue of the peer-reviewed journal Population Health Management revealed that the majority of patients prescribed opioids for chronic pain were unlikely to be taking their medicine in a manner consistent with their prescribed regimen. In the study, titled "Inappropriate Drug Use in the Chronic Pain Population," 938,586 urine toxicology tests conducted on over 500,000 patients prescribed chronic opioid therapy were analyzed using proprietary and state of the art screening methods offered by Ameritox(R).

27 Aug 2009

Kudzu vine root extracts may be developed as a dietary supplement for people with metabolic syndrome

Kudzu, the nuisance vine that has overgrown almost 10 million acres in the southeastern United States, may sprout into a dietary supplement.

27 Aug 2009

GI Dynamics to present additional results of mechanisms of actions clinical study

GI Dynamics, a leader in non-surgical treatments for type 2 diabetes and obesity, today announced that additional results from a previously reported clinical study regarding mechanisms of action will be presented on Saturday, August 29, 2009 by Manoel Galvao Neto, M.D., scientific coordinator, Gastro Obeso Center, Sao Paulo, Brazil and lead investigator for the study, at the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) 14th World Congress in Paris, France.

27 Aug 2009

Amateur boxing leads to increased levels of brain damage markers in spinal fluid

A blood test can now be used to detect brain damage in amateur boxers. Deterioration of nerve cells seems to occur even after a two-month break from boxing. This is shown in a new study from the Sahlgrenska Academy, University of Gothenburg, Sweden.

27 Aug 2009

Studies suggest that venous ischemia causes greater injury than arterial ischemia

The research team led by Professor Guzman-de la Garza of the Autonomous University of Nuevo Leon, Mexico, used a rodent model of intestinal I/R to study the different inflammatory mediators that are associated with venous, arterial or total vascular occlusion.

27 Aug 2009

Study reveals effectiveness of BioElectronics' ActiPatch therapy device for treating heel and foot pain

BioElectronics Corp. (PINKSHEETS: BIEL), the maker of inexpensive, disposable drug-free anti-inflammatory devices, today announced the completion of an important clinical study on heel and foot pain, which was led by David Genecov, M.D. FACS FAAP.

27 Aug 2009

Study finds that some people eliminate more than 90 percent of the arsenic consumed in the diet

Large variations exist in peoples' ability to eliminate arsenic from the body, according to a new study that questions existing standards for evaluating the human health risks from the potentially toxic substance.

27 Aug 2009

Research study indicates that liver regeneration could affect the metabolism of tacrolimus in LDLT

Several studies have shown that living donor liver transplant (LDLT) recipients required smaller doses of tacrolimus compared with deceased donor liver transplant (DDLT) patients, which indicated that liver regeneration could affect the metabolism of tacrolimus in LDLT.

27 Aug 2009

Link between collagen deficiency and osteoarthritis found in mice

Osteoarthritis (OA) and degenerative disc disease (DDD) are common, chronic musculoskeletal disorders. Both diseases cause joint pain, loss of function, and decreased quality of life for the more than 27 million OA and 59 million DDD suffers in the US. According to a 2003 Medical Expenditure Panel Survey, arthritis such as OA costs the U.S. economy nearly $128 billion per year in medical care and indirect expenses including lost wages and productivity.

27 Aug 2009

Relationship between the CD14 variation and the formation of portal lymphoid aggregates discovered

It is still unknown why the natural history of chronic disease caused by hepatitis C virus (HCV), which currently infects 3% of the world's population, varies from mild in some patients to rapidly progressing in others. Age, sex, alcohol consumption and liver sensitivity to gut-derived bacterial endotoxins, were the early factors defined to enhance the risk of fibrosis progression.

27 Aug 2009

Collagen deficiency in mice causes premature development of osteoarthritis and degenerative disc disease

27 Aug 2009

Muscular thighs protect women from developing symptomatic knee osteoarthritis

new study by researchers at the University of Iowa Hospitals and Clinics found that thigh muscle strength does not predict the occurrence of knee osteoarthritis (OA) uncovered in x-rays, but does predict incidence of painful or stiff knee OA. Women with the strongest quadriceps muscles appeared to be protected against the development of knee OA symptoms. Details of this study appear in the September issue of Arthritis Care & Research.

27 Aug 2009

Scientists discover a new way for preventing liver metastases

Scientists in Switzerland have discovered a way to block the growth of human colon cancer cells, preventing the disease from reaching advanced stages and the development of liver metastases. The research, published today in EMBO Molecular Medicine, shows that blocking the so-called Hedgehog-GLI pathway can prevent the growth of tumours, metastatic lesions and cancer stem cells, the cells thought to lie at the root of cancer growth.

27 Aug 2009

Researchers find the method involved in setting up communications network of connections in the brain

In a new study, researchers at the Montreal Neurological Institute and Hospital (The Neuro), McGill University have found an important mechanism involved in setting up the vast communications network of connections in the brain.

27 Aug 2009

Barrier-focused intervention program to increase colonoscopy attendance

In view of low attendance rate for colonoscopy screening for colorectal cancer (CRC), it is necessary to establish effective intervention methods to increase colonoscopy compliance. Many studies have reported that subjective or objective barriers prevent high-risk subjects from undergoing colonoscopy examination, which indicates that barrier-focused intervention might be effective. However, such barrier-focused intervention has not been reported in China.

27 Aug 2009

New technique for diabetes treatment may be in the offing

An exploration of the molecular links between insulin resistance and inflammation may have revealed a novel target for diabetes treatment, say scientists at the John G. Rangos Sr. Research Center, Children's Hospital of Pittsburgh of UPMC. Their findings were published earlier this month in the online version of Diabetes, one of the journals of the American Diabetes Association.

27 Aug 2009

New website launched for comparing mortality risks by gender, age, cause of death and geographic region

A new Web site, www.DeathRiskRankings.com, developed by researchers and students at Carnegie Mellon University, allows users to query publicly available data from the United States and Europe, and compare mortality risks by gender, age, cause of death and geographic region. The Web site not only gives the risk of dying within the next year, but it also ranks the probable causes and allows for quick side-by-side comparison between groups.

26 Aug 2009

Recurrence rate of patients with node-negative gastric cancer can be reduced

Many studies favor an extended lymphadenectomy at the time of a potentially curative gastrectomy for node-positive gastric cancer, and the risk of long-term death tends to decrease when the number of resected lymph nodes increases to about 25. However, few studies have assessed the relative contribution of the total number of resected lymph nodes to the outcome of patients with node-negative gastric cancer.

26 Aug 2009

Medical Research News

UT Southwestern regrets VA's unilateral decision to not renew the Gulf War research contract

Study suspects involvement of PPAR-γ in gastric carcinogenesis

Study confirms inappropriate use of pain medication among the chronic pain population

Kudzu vine root extracts may be developed as a dietary supplement for people with metabolic syndrome

GI Dynamics to present additional results of mechanisms of actions clinical study

Amateur boxing leads to increased levels of brain damage markers in spinal fluid

Studies suggest that venous ischemia causes greater injury than arterial ischemia

Study reveals effectiveness of BioElectronics' ActiPatch therapy device for treating heel and foot pain

Study finds that some people eliminate more than 90 percent of the arsenic consumed in the diet

Research study indicates that liver regeneration could affect the metabolism of tacrolimus in LDLT

Link between collagen deficiency and osteoarthritis found in mice

Relationship between the CD14 variation and the formation of portal lymphoid aggregates discovered

Collagen deficiency in mice causes premature development of osteoarthritis and degenerative disc disease

Muscular thighs protect women from developing symptomatic knee osteoarthritis

Scientists discover a new way for preventing liver metastases

Researchers find the method involved in setting up communications network of connections in the brain

Barrier-focused intervention program to increase colonoscopy attendance

New technique for diabetes treatment may be in the offing

New website launched for comparing mortality risks by gender, age, cause of death and geographic region

Recurrence rate of patients with node-negative gastric cancer can be reduced

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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