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Site in the brain that controls language in right-handed people shifts with aging

...a discovery that might offer hope in the treatment of speech problems resulting from traumatic brain injury or stroke.

9 Oct 2005

Specific gene on chromosome 15 regulates inflammation

A team of international researchers has discovered that a specific gene on chromosome 15 regulates inflammation, a finding with implications for a wide range of disorders, including cancer, cardiovascular disease, diabetes, obesity, Alzheimer's, and infections. The findings are published in the October 9 online issue of Nature Genetics.

9 Oct 2005

Osmolyte findings could have implications for the study of Alzheimer's disease, cystic fibrosis, kidney disease

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have developed a new way to predict the ability of certain small molecules to protect proteins in the cells of a wide variety of organisms living in extreme environments.

9 Oct 2005

Gene variation may play fundamental role in the development and spread of cancer in the body

New research shows that a small gene variation that increases the risk of inherited cancer can also arise during the development of spontaneous, or non-inherited, tumors.

9 Oct 2005

RPL26 and nucleolin play critical roles in controlling the production of p53

Investigators at St. Jude Children's Research Hospital have discovered a previously unrecognized mechanism that controls a key protein linked to the cell's response to stress - a finding that holds promise for new ways to enhance cancer therapies or protect cells from dying after exposure to damaging chemicals or radiation.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Gut antibody could prove to be a promising drug target for Crohn's disease

A collaboration led by the Burnham Institute for Medical Research has found that an antibody which binds to an unusual sugar molecule residing in the gut halts the inflammation seen in Crohn's disease and other intestinal inflammations. The antibody could prove to be a promising drug target for these common chronic intestinal disorders.

9 Oct 2005

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Two New Jersey research teams are reporting discoveries about the biological nature of psychiatric disorders that may bring them closer to the ultimate goal of finding cures for complex diseases, such as autism and schizophrenia.

9 Oct 2005

Novel methodology that can be used to investigate choice and introspection

When evaluating facial attractiveness, participants may fail to notice a radical change to the outcome of their choice, according to a study by researchers at Lund University, Sweden, and New York University. Equally surprising, the study shows that participants may produce confabulatory reports when asked to describe the reasons behind their choices.

9 Oct 2005

Deadly 1918 Spanish flue virus has been reconstructed and characterized

This research, reported in this week's issue of Science, is part of a larger research initiative being led by Adolfo Garcia-Sastre, PhD, Professor of Microbiology and Peter Palese, PhD, Professor and Chairman of Microbiology at Mount Sinai School of Medicine.

5 Oct 2005

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines.

5 Oct 2005

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Subtle differences in other genes -- besides the defective gene known to cause the illness cystic fibrosis -- can significantly modify the inherited disease's severity, a large new multi-center national study has concluded.

5 Oct 2005

Cells inside the hair follicle are true multipotent stem cells

Using an animal model, a research team led by Yann Barrandon at the EPFL (Ecole Polytechnique Federale de Lausanne) and the CHUV (Lausanne University Hospital) has discovered that certain cells inside the hair follicle are true multipotent stem cells, capable of developing into the many different cell types needed for hair growth and follicle replacement.

5 Oct 2005

The cocktail party problem

Known as "the cocktail party problem," the ability of the brain's auditory processing centers to sort a babble of different sounds, like cocktail party chatter, into identifiable individual voices has long been a mystery.

5 Oct 2005

Most comprehensive picture to date of how influenza viruses evolve and are transmitted

In the first large-scale effort of its kind, researchers have determined the full genetic sequence of more than 200 distinct strains of human influenza virus.

5 Oct 2005

Richness of motor training determines not only what we learn but how we learn

Practice makes perfect when people learn behaviors, from baseball pitching to chess playing to public speaking. Biomedical engineers at Washington University in St. Louis have now identified how people use individual experiences to improve performance.

5 Oct 2005

Math1 gene plays a pivotal role in the formation of many of the neurons important in hearing and balance

Close your eyes and imagine you are in a darkened Carnegie Hall. Although it's pitch black, you know you are getting closer to the stage as the music gets louder. If you have been there before, you have a sense of the location of the seats and aisles.

5 Oct 2005

Medical Research News

Site in the brain that controls language in right-handed people shifts with aging

Specific gene on chromosome 15 regulates inflammation

Osmolyte findings could have implications for the study of Alzheimer's disease, cystic fibrosis, kidney disease

Gene variation may play fundamental role in the development and spread of cancer in the body

RPL26 and nucleolin play critical roles in controlling the production of p53

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Gut antibody could prove to be a promising drug target for Crohn's disease

New information regarding the genetic, cellular and neurological bases of susceptibility to autism and schizophrenia

Novel methodology that can be used to investigate choice and introspection

Deadly 1918 Spanish flue virus has been reconstructed and characterized

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Cells inside the hair follicle are true multipotent stem cells

The cocktail party problem

Most comprehensive picture to date of how influenza viruses evolve and are transmitted

Richness of motor training determines not only what we learn but how we learn

Math1 gene plays a pivotal role in the formation of many of the neurons important in hearing and balance

GRK5 protein plays important role in hypertension

Cells have developed a surprising transportation system for their endosomes

Somatic adult stem cell niches - key regulators of stem cell activity in mammary tissue

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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