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Nicotine has an unusual psychological property that may drive dependence

Associate Professor Athina Markou, Ph.D., who is in the Scripps Research Molecular and Integrative Neurosciences Department at Scripps Research’s La Jolla Campus, and Paul Kenny, Ph.D., a former Research Associate in her laboratory, report in an upcoming issue of the journal Neuropsychopharmacology that nicotine has an unusual psychological property that may drive dependence.

28 Sep 2005

Researchers look at pharmacogenomics

When patients receive chemotherapy, 15 percent will have severe side effects while 85 percent will not - even though they're given the same relative dose.

28 Sep 2005

Fever of unknown origin might be a marker of occult cancer

Fever of unknown origin is characterised by a fever of more than 3 weeks’ duration, temperatures of more than 38.3°C and a failure to identify the origin of the fever. Underlying causes of these fevers are difficult to diagnose, but proposed causes are infections, cancers and collagen-vascular diseases.

28 Sep 2005

Nanoparticles as an invisible diet

Utah State University researchers are in the early stages of scientifically tricking the body into eating less and finding a treatment for obesity without dangerous side effects.

28 Sep 2005

Effective removal of face masks from players who sustain c-spine injuries

This fall, as more than a million high school football players take to the gridiron, University of New Hampshire's Erik Swartz is focused on the worst-case scenario.

28 Sep 2005

Flaviviruses immune system defenses in different ways depending on whether they are transmitted by mosquitoes or ticks

"Flaviviruses exact an enormous toll in terms of illness and death worldwide," notes NIAID Director Anthony S. Fauci, M.D. "Because this is a relatively new field of study, everything we learn about how these viruses operate is significant.

28 Sep 2005

C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance

New research shows that levels of C-reactive protein (CRP), produced by the liver and not at the lesion site, correlate with the degree of atherosclerosis.

28 Sep 2005

Chicken virus helps develop novel vaccines

Researchers at the University of South Australia are developing novel vaccines by using a chicken virus to either stimulate or suppress the body's immune system.

28 Sep 2005

Stem cells help regenerate cartilage and bone

UK scientists are working on new methods to regenerate cartilage and bone by delivering genes to stem cells within the body to instruct them to turn into bone cells.

28 Sep 2005

Possible new therapy for lymphoma and leukemia patients

Marty Holmes, a landscaper from Stockton, Calif., had never heard of a regulatory T cell before his doctor suggested that it could be the key to helping him survive his cancer.

28 Sep 2005

Dengue and other viruses may have developed tricks that let them reproduce inside macrophages

A monoclonal antibody that can effectively treat mice infected with West Nile virus has an intriguing secret: Contrary to scientists' expectations, it does not block the virus's ability to attach to host cells. Instead, the antibody somehow stops the infectious process at a later point.

28 Sep 2005

Discovery may lead to development of more effective antibiotics

Researchers at the Georgia Institute of Technology and the John Innes Centre in the United Kingdom have uncovered a mechanism with which disease-causing bacteria may thwart the body's natural defense responses. The findings, which could ultimately lead to the development of more effective antibiotics, appear in the September 29, 2005 issue of the journal Nature.

28 Sep 2005

New Stat1 and interferon findings

By altering a molecule called Stat1, which is involved in cellular immune signaling, scientists have succeeded in making the molecule more responsive and thus more efficient. This old protein with a new twist may eventually be used to improve the body's defense against infection.

28 Sep 2005

Fruit fly discovery could lead to a completely new approach to tackling some cancers

Scientists studying the humble fruit fly have found a family of proteins that enhances the sensitivity of a cell to a hormone that can trigger abnormal growth and cancer. Their discovery could lead to a completely new approach to tackling some cancers and the development of new drugs to stop uncontrolled growth in a wide variety of tumour cells.

28 Sep 2005

Prevalence of "risky" sex in Scotland has doubled in the space of six years

...while unfounded confidence in the HIV negative status of casual partners has also increased, reveals research in Sexually Transmitted Infections.

28 Sep 2005

Emergence of "POZ Parties"

The emergence of "POZ Parties" - parties exclusively for HIV positive men to meet other HIV positive men for sex - signals the potential to spread HIV "superinfection,"suggests research in Sexually Transmitted Infections.

28 Sep 2005

Common form of thalassaemia can be managed without blood transfusion

Haemoglobin E â thalassaemia - the commonest form of severe thalassaemia in many Asian countries - can be managed without transfusion in many patients, suggests a research letter published online today (Thursday September 29, 2005) by The Lancet.

28 Sep 2005

Bleak outlook for overweight Australians

International research into the relationship between obesity and heart failure has uncovered a bleak outlook for already overweight Australians. The research shows that obesity is set to be one of the biggest risks for heart disease over the next decade.

28 Sep 2005

Substance found in cotton plant could help treat psoriasis

A substance found in the cotton plant could help treat the common skin disease psoriasis, according to new research from the Pharmacy School at Sunderland University launched at the British Pharmaceutical Conference in Manchester.

28 Sep 2005

Combination HRT appears to double the breast cancer risk in women who smoke

Older women who have smoked for 11 or more "pack years" - the lifetime equivalent of a pack a day for at least 11 years - face a 30 percent to 40 percent increased risk of developing breast cancer as compared to women who've never smoked, according to new findings from researchers at Fred Hutchinson Cancer Research Center.

28 Sep 2005