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New approach to fighting cancer, based on nanoscale particles

Researchers at Rice University in Texas have developed a new approach to fighting cancer, based on nanoscale particles that can both detect and destroy cancerous cells. The report appears in the April 13 issue of the American Chemical Society's journal Nano Letters.

13 Apr 2005

Link between insomnia and obesity

A possible link between lack of sleep (insomnia) and obesity has been traced to hypocretin/orexin cells in the hypothalamus region of the brain that are easily excited and sensitive to stress, Yale School of Medicine researchers report in the April issue of Cell Metabolism.

13 Apr 2005

People with essential tremor are more likely to develop dementia

People with essential tremor, a movement disorder that causes shaking of the hands, head, voice, or body, are more likely to develop dementia, according to research that will be presented at the American Academy of Neurology 57th Annual Meeting in Miami Beach, Fla., April 9 – 16, 2005.

13 Apr 2005

Worship may help slow the progression of Alzheimer's disease

Spirituality and the practice of religion may help slow the progression of Alzheimer's disease, according to research that will be presented at the American Academy of Neurology 57th Annual Meeting in Miami Beach, Fla., April 9 – 16, 2005.

13 Apr 2005

Problem gambling associated with brain impairments

Pathological gamblers exhibit complex impairments in decision-making and executive function processes associated with the prefrontal cortex of the brain, according to research that will be presented at the American Academy of Neurology 57th Annual Meeting in Miami Beach, Fla., April 9 – 16, 2005.

13 Apr 2005

Researchers show why mutations in a certain few genes, such as the p53 tumor suppressor gene, are found in different cancers

Scientists have identified some of the first genetic triggers for cancer as mutations in specific oncogenes or tumor suppressor genes. Full-blown tumors and metastatic cancers, however, often exhibit many genetic mutations, sometimes dozens in a given tumor. An important scientific question, and one with significant clinical implications, has been what happens after the initial mutation that leads to dangerous later-stage cancers with multiple damaged genes.

13 Apr 2005

Common genetic mutation that increases the risk of inheriting Hirschsprung disease

Gene hunters at Johns Hopkins have discovered a common genetic mutation that increases the risk of inheriting a particular birth defect not by the usual route of disrupting the gene's protein-making instructions, but by altering a regulatory region of the gene. Although the condition, called Hirschsprung disease, is rare, its complex genetics mimics that of more common diseases, such as diabetes and heart disease.

13 Apr 2005

Scientists identifiy protein that seems to control the malignant features of brain tumor cells

Scientists from Wake Forest University School of Medicine have identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. The research is reported in the current issue of Molecular Cancer Research.

13 Apr 2005

Breakthough in stem cell research - three clones of cells from existing human embryonic stem cells

In an Australian first, UNSW researchers have developed three clones of cells from existing human embryonic stem cells. The breakthrough could lead to new treatments for conditions such as diabetes, Parkinson’s disease and spinal cord injury.

13 Apr 2005

Statins used before or after strokes improve outcomes

New research into the use of statins before or after a stroke has shown that a patients recovery after an ischemic stroke can be improved.

12 Apr 2005

Chemical library aids in developing drug system for nerve damage

A researcher studying drug design for nerve damage therapies has gotten her answer to questions by following some old advice: she used the library.

12 Apr 2005

Grandmother smoking can cause childrens asthma

Scientists from the University of Southern California are saying that smoking could have a longer-lasting impact on families' health than ever before realised.

12 Apr 2005

Fish and soy oil help keep hearts healthy

Researchers say that older people who take a daily fish or soy oil supplement can reduce their risk of developing irregular heart rhythm or sudden cardiac death.

12 Apr 2005

Ugly kids get less attention from parents

A researcher at the University of Alberta has shown that parents are more likely to give better care and pay closer attention to good-looking children compared to unattractive ones. Dr. Andrew Harrell presented his findings recently at the Warren E. Kalbach Population Conference in Edmonton, Alberta.

12 Apr 2005

Unconventional wiring of the brain circuits that govern sleep and waking might explain the prevalence of insomnia

Unconventional wiring of the brain circuits that govern sleep and waking might explain the prevalence of insomnia and the condition's association with obesity, according to new work published in the April issue of Cell Metabolism. Characterized by a chronic inability to fall asleep or remain sleeping, insomnia is estimated to affect one in every eight Americans.

12 Apr 2005

New findings about insulin-signaling in the liver could prove useful in understanding type 2 diabetes

A collaborative effort led by The Burnham Institute's Gen-Sheng Feng has created a mouse with improved glucose tolerance and insulin activity in the liver, and generated new findings about insulin-signaling in the liver that could prove useful in understanding the pathogenesis of type 2 diabetes.

12 Apr 2005

Obesity linked to diabetes

A research team headed by Professor Helena Edlund at Umeå University has achieved a breakthrough in our understanding of how obesity causes increased levels of insulin, sugar, and blood fats leading to diseases like type-2 diabetes and liver degeneration. The findings also indicate a direct way to prevent these diseases.

12 Apr 2005

Levels of anti–clotting proteins influence pregancy outcomes

Recurrent miscarriage, stillbirth, preeclampsia, poor fetal growth, preterm delivery and bleeding in pregnancy are influenced by low levels of the anti–clotting proteins Z and S, Yale School of Medicine researchers report in the March issue of Journal of Thrombosis and Haemostasis.

12 Apr 2005

Protein that regulates cholesterol levels may lead to new drug targets in the fight against obesity

A protein that regulates cholesterol levels in the body also is responsible for maintaining a healthy balance between fat storage and fat burning, according to a UT Southwestern Medical Center study that may lead to new drug targets in the fight against obesity.

12 Apr 2005

Low doses of bisphenol–A (BPA) can impair brain function

Low doses of the environmental contaminant bisphenol–A (BPA), widely used to make many plastics found in food storage containers, including feeding bottles for infants, can impair brain function, leading to learning disabilities and age–related neurodegenerative diseases, according to Yale researchers and colleagues.

12 Apr 2005