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Breakdown in brain cell communication may contribute to the most common biochemical cause of mental retardation

The process is akin to a baseball game gone bad. Imagine if a pitcher were joined by six players simultaneously winding up on the mound. Crouched behind home plate, the single catcher would soon be overwhelmed. Even if the coach sent in teammates to catch the extra balls, confusion would reign on the field.

12 Apr 2005

Is late diagnosis of lung cancer inevitable?

A study by researchers into the diagnosis of patients with lung cancer suggests that avoidable patient delays in reporting symptoms of the disease is an important factor in its treatment.

12 Apr 2005

Novel findings in Balo's concentric sclerosis may shed light on pathology of MS

Researchers partly funded through the National MS Society’s “MS Lesion Project” report that a novel mechanism known as “tissue preconditioning” may explain the pattern of tissue damage that occurs in Baló’s concentric sclerosis, a rare, severe disease similar to MS, and may offer clues to a similar phenomenon in MS. Hans Lassmann, MD (Medical University of Vienna, Wien) and colleagues, including Society grantee Claudia Lucchinetti, MD (Mayo Clinic and Foundation, Rochester, MN), report their findings in Brain.

12 Apr 2005

Cardiac stem cells come closer to clinic

The laboratory of MDA grantee Kenneth Chien at the University of California-San Diego announced in a recent issue of Nature that its researchers have discovered in the hearts of mice, rats and humans a new type of stem cell that can become a mature cardiac cell.

12 Apr 2005

Vaccine against the virus that causes cervical cancer and genital warts shows promise

A vaccine against the virus that causes cervical cancer and genital warts could reduce persistent infection and disease by 90%, suggest the results of a randomised trial published online by The Lancet Oncology.

12 Apr 2005

Researcher grows new insulin-secreting beta cells from pancreatic tissue

JDRF-funded researchers in Canada and Massachusetts have stimulated the birth of new insulin-secreting beta cells by treating human islets with a mixture of two naturally occurring peptides: epidermal growth factor (EGF) and gastrin.

12 Apr 2005

Race influences how we cope with cancer

White patients cope better with the pressure of cancer than their British Asian counterparts according to research published on-line in the British Journal of Cancer.

12 Apr 2005

Antimicrobial soaps may expose consumers to significant quantities of chloroform

Researchers at Virginia Tech have discovered that the use of antimicrobial soaps and other products may unnecessarily be directly exposing consumers to significant quantities of chloroform.

12 Apr 2005

Research challenges the traditional explanation for the causes of diastolic heart failure

New research from Columbia University Medical Center is challenging the traditional explanation for the causes of the most common type of heart failure, traditionally called diastolic heart failure.

12 Apr 2005

Mobile telephones do not increase risk of brain tumours

Much to the relief of millions of users, according to a new Danish study using a mobile telephone does not appear to increase the risk of brain tumours.

11 Apr 2005

New drugs help the immune system kill cancer cells

Researchers at the Lankenau Institute for Medical Research (LIMR) announced today that they have discovered an effective way to enlist the immune system to help chemotherapy destroy breast cancer cells. The work, led by LIMR researchers Alexander J. Muller and George C. Prendergast, is reported in the March 2005 edition of the leading international medical journal Nature Medicine.

11 Apr 2005

Tissue engineering to grow bone, ligaments and cartilage

A future in which laboratory-grown organs and stimulated growth of muscle, bones and nerves could play a major role in treating medical conditions was revealed at a recent Tissue Engineering Symposium at Wake Forest University Baptist Medical Center.

11 Apr 2005

A baby's understanding of language may begin with its own name

A baby's understanding of language may begin with its own name, which a baby uses to break sentences into smaller parts so it can learn other words, according to new research by Texas A&M University psychologist Heather Bortfeld, who studies language development in infants and children.

11 Apr 2005

Laughter best medicine for hope

Laughter might be the best medicine for transforming the faintest of glimmers of hope into an eternal spring, reveals research at Texas A&M University that shows humor may significantly increase a person's level of hope.

11 Apr 2005

Dental patients agreeable to tobacco interventions

Dental patients don't mind if their dentists give them a nudge to stop using tobacco products, according to the findings of survey conducted at the Case Western Reserve University School of Dental Medicine.

11 Apr 2005

Faster, more accurate diagnostic test for Sjogren's syndrome

Researchers in Japan are developing a faster, more accurate diagnostic test for Sjögren’s (SHOW-grins) syndrome, an incurable autoimmune disorder characterized by chronically dry eyes and dry mouth.

11 Apr 2005

Researchers discover mechanism by which tumours support their own growth

In a recent issue of the American Journal of Pathology, the Bremen researchers report their findings on a signalling molecule called "High Mobility Group Protein B1" (HMGB1). As a signal sent by tumour cells HMGB1 proteins induce sprouting of blood vessels that supply tumours with oxygen, thus promoting tumour growth.

11 Apr 2005

New blood test improves the ability to diagnose or exclude congestive heart failure

A new blood test that measures a particular marker of cardiac distress can markedly improve the ability to diagnose or exclude congestive heart failure in patients with shortness of breath who come to hospital emergency departments.

11 Apr 2005

Research suggests a central role for NMDA receptors in learning and memory

Learning and memory are processes that link experience with behavior and therefore play central roles in our daily experience. That there exists a physical basis for these processes seems at first hard to imagine--except for the fact that physical disruptions in the brain, such as stroke or disease, can make them go wrong.

11 Apr 2005

Moderate levels of exercise may not be enough to control mild hypertension

Moderate levels of exercise may not be enough to control mild hypertension in men and women over age 55, the age group most at risk of later developing potentially fatal heart failure, a new four-year study reports. The findings by researchers at Johns Hopkins, to be published in the journal Archives of Internal Medicine online April 11, call into question the effectiveness of national guidelines on exercise for lowering blood pressure in older people.

11 Apr 2005