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Water management is the key to regulating cell volume

...says Dutch researcher Bas Tomassen. He investigated the uptake and secretion of water by the plasma membrane of animal and human cells.

27 Sep 2005

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

A team from the University of Pennsylvania School of Medicine has shown that by using a cancer vaccine based on the bacterium Listeria monocytogenes, they can cure mice with established breast tumors. Cancer vaccines, which are more properly described as immunotherapy, work by boosting an immune response against tumor-associated antigens.

27 Sep 2005

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Johns Hopkins scientists have discovered that a drug currently being tested against cancers might help children with a rare, fatal condition called Hutchinson-Gilford progeria syndrome, which causes rapid, premature aging.

27 Sep 2005

Gene responsible for Neuralgic Amyotrophy identified

Neuralgic Amyotrophy is a painful disorder of the peripheral nervous system. This heritable disease causes prolonged acute attacks of pain in the shoulder or arm, followed by temporary paralysis.

27 Sep 2005

Stem cells may unlock the secrets to healing the brain

These amazing cells have the remarkable potential to develop into many different cell types in the body and have to potential to revolutionise medical science.

27 Sep 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

Nature may play a larger role than nurture when it comes to family relationships

Researchers from the University of Texas at Austin and George Washington University in Washington, D.C., used data on 674 families, each with a same-sex adolescent pair, to evaluate the factors that made up the relationships and individual personalities.

26 Sep 2005

Plans to develop a "universal beta-cell line" - treatment for type 1 diabetes

Transplantation of insulin-producing pancreatic beta-cells shows great promise as a treatment for type 1 diabetes, but development of this therapy has been hampered by a severe shortage of donor beta-cells, which are obtained from decreased human donors.

26 Sep 2005

Findings increase understanding of how an organism's body size is determined and how the speed of its development is controlled

In particular, the work sheds light on the molecular and cellular pathways that act to convey information about a growing organism's size, as well as on pathways that use that information to correctly time critical transitional events during development.

26 Sep 2005

Discovery of molecule that causes transverse myelitis

Hopkins researchers have discovered a single molecule that is a cause of an autoimmune disease in the central nervous system, called transverse myelitis (TM), that is related to multiple sclerosis.

26 Sep 2005

Antibody in humans that quickly fights the smallpox virus

Researchers at the La Jolla Institute for Allergy & Immunology (LIAI) have made a major advancement toward protecting society against a smallpox outbreak by identifying an antibody in humans that quickly fights the smallpox virus.

26 Sep 2005

Loss of body mass over time appears to be strongly linked to older adults' risk of developing Alzheimer's disease

The findings are the first to associate decline in body mass index (BMI) with the eventual onset of AD. The researchers suggest that the loss of body mass reflects disease processes and that change in BMI might be a clinical predictor of the development of AD.

26 Sep 2005

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

The relationship between tissue rigidity and tumor formation is fairly well established; however, what is not so well understood is what happens on a molecular level that contributes to such stiffness.

26 Sep 2005

Tobacco industry hindered federal and international regulations on pesticide use

The tobacco industry coordinated cross-industry campaigns to delay and weaken federal and international regulations on pesticide use, according to new findings by University of California - San Francisco (UCSF) researchers.

26 Sep 2005

Researchers gain insights into how malaria pathogen destroys the cells in which it resides

By specially tagging the outer and inner membranes of red blood cells infected with the malaria parasite and tracking the cellular changes that precede the cell bursting event that disperses parasites to other blood cells, a group of researchers has deepened our understanding of how the malaria pathogen destroys the cells in which it resides.

26 Sep 2005

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Their findings, which may point to new approaches to developing improved treatment options for the disease, are published in the journal Nature.

26 Sep 2005

A new, less toxic way to treat malignant melanoma

A new, less toxic way to treat malignant melanoma (skin cancer) is being developed by medicinal chemists at Reading University. They have produced a range of prodrugs: compounds that offer the potential to be converted to toxic molecules only within the vicinity of tumours. These prodrugs aim to reduce the toxicity of treatment.

26 Sep 2005

Extreme gene pin-pointed

One teenager likes to snowboard off a cliff. Another prefers to read a book and wouldn't think of trading places. Why these differences exist is a mystery, but for the first time researchers have identified a possible genetic explanation behind risk-seeking behavior.

26 Sep 2005

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine identified three novel mutations in two receptor tyrosine kinases in glioblastoma tumors using high throughput sequencing.

26 Sep 2005

Pharmacists can drastically reduce patients worries about using steroids

For those people who suffer from eczema, the use of topical corticosteroids is high up on their list of concerns: How should they be used? And are they safe?

26 Sep 2005

Medical Research News

Water management is the key to regulating cell volume

Cancer vaccine based on the bacterium Listeria monocytogenes, can cure mice with breast tumors

Farnesyl transferase inhibitors may help chidren with Hutchinson-Gilford progeria syndrome

Gene responsible for Neuralgic Amyotrophy identified

Stem cells may unlock the secrets to healing the brain

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

Nature may play a larger role than nurture when it comes to family relationships

Plans to develop a "universal beta-cell line" - treatment for type 1 diabetes

Findings increase understanding of how an organism's body size is determined and how the speed of its development is controlled

Discovery of molecule that causes transverse myelitis

Antibody in humans that quickly fights the smallpox virus

Loss of body mass over time appears to be strongly linked to older adults' risk of developing Alzheimer's disease

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

Tobacco industry hindered federal and international regulations on pesticide use

Researchers gain insights into how malaria pathogen destroys the cells in which it resides

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

A new, less toxic way to treat malignant melanoma

Extreme gene pin-pointed

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Pharmacists can drastically reduce patients worries about using steroids

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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