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Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

In a paper appearing online in advance of print publication of the October 1 issue of the Journal of Clinical Investigation, Adam Boruchov and colleagues from Memorial Sloan Kettering Cancer Center dissect the contributions of CD32 isoforms in human dendritic cell (DC) activation and function.

26 Sep 2005

Researchers discover way to dramatically boost the output of immune system cells from the thymus

Mayo Clinic researchers have discovered a way to dramatically boost the output of immune system cells from the thymus, which may lead to improved cancer vaccines, as well as to ways to otherwise strengthen immune responses.

26 Sep 2005

How the vertebrate eye, as we know it, has emerged over evolutionary time

The evolution of complex and physiologically remarkable structures such as the vertebrate eye has long been a focus of intrigue and theorizing by biologists.

26 Sep 2005

Delicate balance of induction and inhibition in determining tooth cusps

One of the remaining challenges for evolutionary developmental studies of mammals, whose evolution is best known from their teeth, is how their tooth shape is altered during development.

26 Sep 2005

Raf Kinase Inhibitor Protein plays a role in controlling the active movement of cells

University of Illinois at Chicago researchers report that a protein that regulates key signaling pathways in cells also plays a role in controlling the active movement or migration of cells. The finding may suggest new pharmaceutical therapies for treating a variety of diseases, including cancer.

26 Sep 2005

Most Americans rate medical research as a high national priority

...and strongly support greater public and private funding, according to an article in the Journal of the American Medical Association (JAMA), a theme issue on medical research.

26 Sep 2005

Daylight savings changes may help extend the life and health of people's teeth and bones

Beginning in 2007, daylight savings time will be extended by almost a month. This additional amount of daylight may also help extend the life and health of people's teeth and bones. That's because vitamin D, also known as the "sunshine vitamin," is made by the body through casual and minimal sun exposure.

26 Sep 2005

Adult human neural stem cells used to successfully regenerate spinal cord tissue

Researchers at the UC Irvine Reeve-Irvine Research Center have used adult human neural stem cells to successfully regenerate damaged spinal cord tissue and improve mobility in mice.

26 Sep 2005

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Bacteria-eating cells that generally fight infection may cause dementia in HIV patients, University of Florida and University of California at San Francisco researchers have found.

26 Sep 2005

Leaving deprivation out of standard risk assessments for heart disease is potentially denying life saving treatment to those who need it most

A person's estimated chances of developing heart disease, and being allocated "primary preventive" treatment, is currently calculated using the standard risk factors of smoking, blood pressure, cholesterol, age, sex, and diabetes. These are typically pulled together in the internationally used Framingham Risk Score.

26 Sep 2005

Downward mobility hits men far harder than women

The findings are based on survey responses from 503 men and women taking part in the Newcastle Thousand Families Study, all of whom were born in May and June 1947 to mothers living in Newcastle upon Tyne, north east England.

26 Sep 2005

Smaller prefrontal cortex is associated with early-onset drinking

Previous research has shown that alcohol-use disorders (AUDs) are associated with abnormalities of the prefrontal cortex, thalamus and the cerebellar hemispheres in adults.

26 Sep 2005

Heart disease patients face greater risk of PTSD

Heart attack patients, and most likely those with other forms of heart disease, run an increased risk of developing post-traumatic stress disorder, says a new research review done in Denmark and the Netherlands.

22 Sep 2005

Dilute bleach neutralizes the mold allergens that cause most mold-related health complaints

Researchers at National Jewish Medical and Research Center have demonstrated that dilute bleach not only kills common household mold, but may also neutralize the mold allergens that cause most mold-related health complaints.

22 Sep 2005

Change in gene may be underlying molecular defect in some colorectal cancers

Inactivation of a DNA repair gene may be an early step in the development of sporadic colorectal tumors, and detection of the molecular basis for this inactivation may ultimately be useful in risk assessment for colorectal cancer, according to a new study in the current issue of the Journal of the National Cancer Institute.

22 Sep 2005

Prediction of new polymorph of the Alzheimer's drug, piracetam

A challenge, presented at last year's e-Science All Hands meeting, has resulted in an e-Science project achieving one of the holy grails of the pharmaceutical industry - the computational prediction of a previously unidentified crystal structure, or polymorph, of a drug molecule.

22 Sep 2005

Presence of environmental chemicals in human milk does not necessarily indicate health risks for infants

"We strongly emphasize that the mere presence of an environmental chemical in human milk does not indicate that a health risk exists for breast-fed infants," said Cheston M. Berlin, Jr., M.D., Penn State University professor of pediatrics and pharmacology.

22 Sep 2005

Botox helps explain possible causes of nerve diseases

Botox, used by Hollywood stars to smooth out facial wrinkles, is playing an important role in UQ research to understand how nerve cells communicate with each other.

22 Sep 2005

HDL cholesterol helps prevent blocked arteries and heart attack

Cardiology experts at Johns Hopkins have issued interim guidelines for physicians on how best to treat low levels of HDL cholesterol, the so-called good cholesterol, which helps keep arteries clear from the buildup of LDL cholesterol, the so-called bad cholesterol.

22 Sep 2005

John Hopkins scientists uncover "tags" that force proteins to cell surface

Johns Hopkins scientists have discovered internal "shipping labels" that allow -- and perhaps force -- hundreds if not thousands of proteins to get to the surface of cells and stay there.

22 Sep 2005

Medical Research News

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

Researchers discover way to dramatically boost the output of immune system cells from the thymus

How the vertebrate eye, as we know it, has emerged over evolutionary time

Delicate balance of induction and inhibition in determining tooth cusps

Raf Kinase Inhibitor Protein plays a role in controlling the active movement of cells

Most Americans rate medical research as a high national priority

Daylight savings changes may help extend the life and health of people's teeth and bones

Adult human neural stem cells used to successfully regenerate spinal cord tissue

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Leaving deprivation out of standard risk assessments for heart disease is potentially denying life saving treatment to those who need it most

Downward mobility hits men far harder than women

Smaller prefrontal cortex is associated with early-onset drinking

Heart disease patients face greater risk of PTSD

Dilute bleach neutralizes the mold allergens that cause most mold-related health complaints

Change in gene may be underlying molecular defect in some colorectal cancers

Prediction of new polymorph of the Alzheimer's drug, piracetam

Presence of environmental chemicals in human milk does not necessarily indicate health risks for infants

Botox helps explain possible causes of nerve diseases

HDL cholesterol helps prevent blocked arteries and heart attack

John Hopkins scientists uncover "tags" that force proteins to cell surface

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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