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Active feedback improves pharmacist participation in heart failure treatment

Pharmacists who received active feedback about their heart failure patients increased the frequency of their patient interactions and prescribed more heart failure medication adjustments, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Intensive blood pressure treatment reduces cardiovascular risk in people with Type 2 diabetes

An intensive treatment approach to lowering high systolic blood pressure in people with Type 2 diabetes led to a reduced risk of heart attack, stroke, heart failure and death due to cardiovascular disease when compared to a standard treatment approach, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Anticoagulants fail to reduce cognitive decline in younger adults with AFib

Prescribing anti-clotting medications to adults younger than age 65 who have atrial fibrillation (AFib) but no other risk factors for stroke did not reduce the risk of cognitive decline, stroke or transient ischemic attack (TIA), according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Ablation may offer better outcomes than medication for ventricular tachycardia

Ablation, a procedure to treat abnormal electrical short circuits caused by a heart attack and is usually reserved for patients who do not improve with medication, may be a better first-line treatment for heart attack survivors experiencing dangerous rapid heartbeat episodes, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

SGLT2 inhibitor canagliflozin shown to improve kidney oxygenation in diabetes patients

Type 2 diabetes can lead to diabetic kidney disease, but a class of drugs that cause the kidneys to remove glucose through urine has been gaining attention.

18 Nov 2024

NSAIDs raise bleeding risk in patients taking blood thinners

People who take an anticoagulant medicine double their risk of an internal bleed if they take a type of painkiller called a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen, diclofenac or naproxen, according to research published in the European Heart Journal [1] today (Monday).

18 Nov 2024

Hormone therapy and puberty blockers alter skeletal size in transgender individuals

Skeletal size may be altered by gender-affirming hormone therapy only if puberty has also been suppressed during adolescence, according to research presented at the 62nd Annual European Society for Paediatric Endocrinology Meeting in Liverpool.

18 Nov 2024

Delayed puberty in boys could lead to new follow-up healthcare routines in the future

Swedish young men who went through late puberty during adolescence are more likely to use healthcare services later in life, according to research presented at the 62nd Annual European Society for Paediatric Endocrinology Meeting in Liverpool.

18 Nov 2024

New mindfulness therapy offers hope for teenagers struggling with depression

Researchers have developed a mindfulness therapy tailored specifically to appeal to teenagers to help them cope with increasing levels of depression and mental health problems.

18 Nov 2024

Study links cannabis use to genotoxicity and transgenerational health impacts

Cannabis exposure leads to genetic damage and accelerated aging, raising concerns about its transgenerational health effects and public health implications.

18 Nov 2024

Air pollution spurs inflammation in heart failure patients

A new study by heart researchers at Intermountain Health in Salt Lake City finds that patients with heart disease, specifically those with heart failure, are especially vulnerable to the impacts of air pollution and poor air quality and can take steps to protect themselves.

18 Nov 2024

Phase 2 study evaluates safety and efficacy of asunercept in COVID-19 patients

The ASUNCTIS trial evaluated asunercept's safety and efficacy in COVID-19, showing trends toward faster recovery despite not meeting statistical significance.

18 Nov 2024

Monash researchers develop model to tackle weight stigma in pregnancy and beyond

People with larger bodies commonly face a pervasive, resilient form of social stigma, often facing discrimination in the workplace as well as in educational and healthcare settings.

18 Nov 2024

Diabetes rates skyrocket globally with millions left untreated

The total number of adults living with either type 1 or type 2 diabetes in the world has surpassed 800 million - over four times the total number in 1990, according to findings from a global analysis published ahead of World Diabetes Day in The Lancet.

18 Nov 2024

Can music therapy be the breakthrough dementia care desperately needs?

Music therapy reduces distress and improves well-being in advanced dementia by meeting unmet needs, enhancing caregiver-patient understanding, and fostering humanizing connections in institutional care settings.

18 Nov 2024

Spermidine regulates RIPK1 to combat diabetes and vascular damage

Researchers reveal that spermidine-mediated acetylhypusination of RIPK1 suppresses necroptosis and insulin resistance, offering potential therapeutic strategies for type 2 diabetes.

18 Nov 2024

Neoantigen DNA vaccines improve survival and immunity in triple-negative breast cancer patients

A new phase 1 trial demonstrates the safety and effectiveness of personalized neoantigen DNA vaccines, showing promising immune responses and improved recurrence-free survival in high-risk triple-negative breast cancer patients.

17 Nov 2024

Engineered SNIPRs transform CAR T-cell precision for safer cancer therapy

Researchers developed SNIPRs, innovative receptors that sense soluble ligands, enabling precise therapeutic control in CAR T-cells. This breakthrough enhances tumor targeting while reducing off-target effects, paving the way for advanced synthetic biology applications.

17 Nov 2024

Growth hormone-releasing hormone transforms therapeutic potential in health and chronic disease

Researchers review the biological activities of growth hormone-releasing hormone and its analogs.

17 Nov 2024

Engineered virus-like particles evolve for superior gene delivery efficiency

Researchers developed a barcoded directed evolution system for engineered virus-like particles (eVLPs), creating a fifth-generation (v5) eVLP with enhanced production, transduction, and gene-editing efficiency. This system could pave the way for improved gene delivery vehicles in therapeutic applications.

17 Nov 2024