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Scientists uncover shared gene signatures that reveal how mammals age

Researchers mapped more than 11,000 transcriptomes across mice, rats, macaques, and humans, revealing conserved molecular signatures of aging and mortality across tissues, species, and cell types. The study developed interpretable transcriptomic clocks that track age, mortality-related molecular change, chronic disease signals and responses to lifespan-altering interventions.

29 May 2026

Experimental vaccine triggers broadly neutralizing HIV antibodies in macaques

For years, researchers have been hoping for vaccines that protect people against not just one strain of HIV, but every strain of the quickly mutating virus.

28 May 2026

UCLA researchers identify brain circuit controlling memory organization

When a person has a new experience, their brain faces a subtle but critical decision: should this experience be categorized with other stored memories, or should it be filed away as its own new memory? Getting it right allows the brain to help people navigate the world.

28 May 2026

Blood biomarkers may detect Alzheimer’s risk before symptoms appear

For the first time, researchers found blood biomarkers for Alzheimer's disease that correlated with minor cognitive differences in midlife adults who did not have dementia.

28 May 2026

Gut changes linger years after polyp removal and may signal colorectal cancer risk

Researchers found that women who had undergone colorectal adenoma resection still showed gut microbiome and fecal metabolome alterations an average of about 12 years later. These persistent changes partly resembled colorectal cancer-associated patterns, suggesting that the host-microbiome axis may remain altered along the adenoma-cancer continuum.

28 May 2026

AI maps how brain fluids move to clear waste

MR-AIV uses physics-informed AI and DCE-MRI scans to infer 3D brain-wide fluid movement in mice without direct flow measurements. The method distinguished slow diffusion-dominated transport from faster advective flow and estimated pressure and permeability patterns linked to brain waste clearance.

28 May 2026

AI-powered atlas maps immune structures across multiple cancer types

In a new study published today in Science, researchers from The University of Texas MD Anderson Cancer Center developed a spatial atlas of specialized immune structures, called tertiary lymphoid structures (TLSs), across multiple cancer types.

28 May 2026

Low protein intake linked to declining physical function with age

Researchers have found that consuming lower amounts of protein-rich foods may negatively affect physical functioning as people grow older, underscoring the vital function protein plays in preserving mobility and muscle strength in adulthood.

28 May 2026

Brain transposons may influence aging and neurodegenerative disease progression

Transposable elements (TEs), also called transposons, are DNA sequences capable of moving or replicating from one location to another within a genome.

28 May 2026

Study uncovers a biological link between chronic oral inflammation and female fertility

Chronic oral inflammation may impair female fertility by triggering a systemic immune response that affects the ovaries.

28 May 2026

Scientists identify new therapeutic target for deadly prostate cancer

Researchers at Columbia University Irving Medical Center have identified a gene that drives the development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease.

28 May 2026

New nutrient-sensing mechanism offers hope for neurodegenerative diseases

Researchers from the University of Cambridge highlight new ways that neurons and many cell types use to sense nutrients - opening potential novel therapeutic avenues for disorders such as Alzheimer's and Parkinson's disease.

28 May 2026

Drug-filled nanofibers offer potential breakthrough treatment for brain cancer

Researchers with the University of Cincinnati and Johns Hopkins Medicine developed a potential treatment for brain cancer that uses nanofibers embedded with a combination of drugs that work in concert to target tumors.

28 May 2026

‘Natural bypass’ of the heart helps doctors avoid risky cardiac surgeries

Your heart already has its own built-in bypass system that predicts whether the heart muscle is alive or dead - according to new research from the University of East Anglia and Norfolk and Norwich University Hospital.

28 May 2026

Virtual AI mouse tests nanomedicine without using living animals

When a tumor manages to nestle itself in the brain of a living being, it has - from the tumor's perspective - done something particularly clever.

28 May 2026

Vitamin deficiencies may contribute to chronic fatigue and low motivation

With less time and more work, chronic fatigue has become a moniker of modern society. However, this not only reduces the quality of life but also constitutes as a social issue that affects work efficiency and leads to accidents.

28 May 2026

Gut microbiota may determine severity of life-threatening sepsis infections

Why do some people recover easily from bacterial infections while others rapidly deteriorate into life-threatening sepsis? According to a new study, the answer may lie not only in the invading pathogen itself, but also in the microorganisms already living inside the gut.

28 May 2026

Scientists rethink GLP-1 delivery to improve dosing, tolerability, and adherence

The review highlights nanocarriers, microspheres, hydrogels, microneedles, long-acting formulations, and co-formulations as promising but mostly early-stage strategies that still require stronger long-term clinical evidence.

27 May 2026

How do everyday spices help protect the heart?

A Nutrition Reviews supplement article reviewed controlled studies showing that culinary spice and herb blends may improve selected cardiometabolic risk markers, including post-meal triglycerides, insulin responses, inflammation, endothelial function, and 24-hour blood pressure. The review also highlighted exploratory evidence that spices and herbs may influence immune-cell activity, circulating phytochemical metabolites, and gut bacterial composition, while emphasizing the need for longer and more diverse studies.

27 May 2026

Traditional medicinal plant extract shows promising anti-skin aging effects

Announcing a new publication for Acta Materia Medica journal. Vicatia thibetica de Boiss (V. thibetica), a traditional medicinal and edible plant used by the Bai ethnic group in China, is known for its effects in tonifying qi, nourishing the blood, dispelling dampness, and relieving itching.

27 May 2026