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Gestational diabetes alters the placenta at the molecular level, study reveals

Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely understood.

18 Dec 2025

Scientists unravel how citrin deficiency can trigger fat buildup in the liver even in lean individuals

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. and a leading research center for diabetes and other life-threatening illnesses, have unraveled how citrin deficiency (CD), a rare genetic disorder that prevents the liver from converting food into energy efficiently, can trigger fat buildup in the liver - even in lean individuals.

18 Dec 2025

Folate deficiency drives genetic changes linked to lung cancer

Genetic alterations lie at the heart of cancer development, but scientists may have been overlooking a powerful driver of these changes—the everyday nutrients that feed our cells.

18 Dec 2025

Ventilator mode and tube cuff design reshape airflow in the intubated trachea

Mechanical ventilation saves lives, but the airflow it produces inside an intubated airway can also shape conditions linked to complications during long-term support.

18 Dec 2025

Social living allows genetic effects to spread through the gut microbiome

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published today in Nature Communications.

18 Dec 2025

Flu wave’s hidden cost on people with cystic fibrosis

People with cystic fibrosis (CF) are uniquely vulnerable to the flu wave currently ripping through the UK, a clinical researcher from The University of Manchester has warned.

18 Dec 2025

New research highlights varied cold perception across body tissues

Universidad Miguel Hernández de Elche A research team led by Félix Viana, co-director of the Sensory Transduction and Nociception laboratory at the Institute for Neurosciences (IN), a joint research center of the Spanish National Research Council (CSIC) and Miguel Hernández University of Elche (UMH), has demonstrated that the body uses different molecular mechanisms to detect cold in the skin and in internal organs.

18 Dec 2025

Study reveals how lung macrophages amplify allergic inflammation in the lungs

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune responses.

18 Dec 2025

Eating high-fat cheese and cream may be linked to lower dementia risk

Eating more high-fat cheese and high-fat cream may be linked to a lower risk of developing dementia, according to a new study published on December 17, 2025, in Neurology, the medical journal of the American Academy of Neurology.

17 Dec 2025

Genetic differences can affect the effectiveness of antibody therapies

The genome differs from person to person in thousands of positions. In some cases, this means that proteins have a different building block in certain regions, rendering some antibody-based therapies ineffective, report researchers from the University of Basel, Switzerland.

17 Dec 2025

Cannabis use alters sleep stages in people with chronic pain

The most frequently reported reasons for medicinal cannabis use are for pain relief and improvements in sleep.

17 Dec 2025

Social isolation emerges as a key, independent risk factor for cognitive decline

Using longitudinal data from the US Health and Retirement Study, this study applied causal inference modeling to disentangle the independent and joint effects of social isolation and loneliness on later-life cognitive function. It shows that reducing social isolation is associated with modest but meaningful protection against cognitive decline, with loneliness mediating only a small proportion of this effect.

17 Dec 2025

AI analysis of chest X-rays may reveal early signs of aging

Artificial intelligence may be able to reveal how fast your body is aging by analyzing a chest X-ray, according to a new study published in The Journals of Gerontology. Researchers found that a deep learning model was able to detect subtle, age-related changes in the heart, lungs, and overall health more effectively than leading DNA-based "epigenetic clocks."

17 Dec 2025

Research reveals how the gut microbiome supports successful pregnancy

Gut microbes may play a key role in training a mother's immune system to adapt to the developing fetus during pregnancy, according to a preclinical study by Weill Cornell Medicine investigators.

17 Dec 2025

Novel mRNA therapy rejuvenates immune function in aging mice

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that this is possible with an innovative approach.

17 Dec 2025

Strong heart health lowers long-term death risk in cancer survivors

Higher Life’s Simple 7 cardiovascular health scores were associated with lower long-term all-cause and cancer mortality in cancer survivors from a large Italian cohort. Inflammation, resting heart rate, and vitamin D statistically explained a substantial share of these associations, supporting shared cardiometabolic pathways across cancer and cardiovascular disease.

17 Dec 2025