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Scientists redesign CAR-T cells to fight more than cancer

This review examines how CAR-T cell therapy is expanding beyond blood cancers into solid tumors, autoimmune diseases, chronic viral infections, and next-generation immune-cell platforms. It highlights promising engineering advances, including universal CAR-T cells, in vivo delivery, CAR-NK cells, and safety switches, while emphasizing unresolved challenges in durability, safety, scalability, and global access.

29 Apr 2026

Study reframes ADHD as disorder of energy regulation

The number of people in Europe diagnosed with attention deficit hyperactivity disorder (ADHD) has continued to rise steadily, not only among children, but increasingly among adults and women.

28 Apr 2026

Wearable sweat sensor tracks vitamin levels in real time

Researchers developed a wearable electrochemical patch that detects six vitamins in sweat at nanomolar levels, combining sweat induction, microfluidic sampling, wireless readout, and pH/ionic-strength calibration. Human testing focused mainly on vitamin B9, showing sweat levels rose after supplementation or a vitamin B9-rich diet and correlated with serum levels, supporting future use for non-invasive nutrition trend monitoring.

28 Apr 2026

Epigenetic changes reshape Dicer enzyme function in cancer and reproduction

Activation of a specific part of the Dicer enzyme can change its shape in a way that affects its critical role in proper cell division, with implications for both cancer biology and fertility, according to researchers at The University of Texas MD Anderson Cancer Center.

28 Apr 2026

UIC researchers develop anti-cancer therapy inspired by bacteria in tumors

Researchers at the University of Illinois Chicago have developed an anti-cancer therapy inspired by bacteria found in cancer tumors.

28 Apr 2026

TikTok chatter could help predict where the opioid crisis is heading next

A large-scale analysis of 569,581 TikTok comments found that opioid-related discussions may help track and forecast synthetic opioid overdose mortality in the US. Recovery, harm reduction, drug use, drug sourcing, and loss-related conversations provided near-real-time signals that improved 6-month forecasting accuracy.

28 Apr 2026

Why H2N2 flu is back on the pandemic preparedness radar

A historical review in Vaccine warns that global H2N2 immunity has sharply declined since the 1957 Asian influenza pandemic, leaving most people without H2-specific protection if the virus re-emerges. The authors highlight animal reservoirs, waning birth-cohort immunity, and modern H2 vaccine platforms as key priorities for pandemic preparedness.

28 Apr 2026

New blood-based method identifies testicular cancer missed by standard tests

Mayo Clinic researchers have developed a blood-based method that may help detect germ cell tumors, the most common type of testicular cancer, including cases that do not show up on standard blood tests, according to a study published in Nature Communications.

28 Apr 2026

Lab-grown skin organoids provide new insights into blood vessel pathology

New research has shown that single blood vessel cells that appear in the earliest stages of lab-grown skin organoids have the ability to form complex microvascular networks that grow and mature over time.

28 Apr 2026

Hepatitis C infection associated with reduced portal insulin levels

Insulin resistance is a common extrahepatic manifestation of hepatitis C virus (HCV) infection (HCVi), but its mechanism is poorly understood.

28 Apr 2026

New clinical guidelines significantly reduce opioid prescriptions after ear surgery

A new retrospective study published in OTO Open, the open-access journal of the American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF), demonstrates that the Clinical Practice Guideline (CPG) Opioid Prescribing for Analgesia After Common Otolaryngology Operations has had a measurable and sustained impact on prescribing practices following parotidectomy, which a surgical procedure to remove the parotid gland.

28 Apr 2026

Scientists identify specialized cells that trigger bone marrow cavity growth

Bone marrow is the spongy tissue located within the hollow center of bones, serving as the primary site for the continuous production of red blood cells, platelets, and white blood cells.

28 Apr 2026

Harvard scientists create first detailed map of smell receptors

For most of us, the sense of smell is an integral part of everyday life; it plays a critical role in providing information about our surroundings, alerting us to potential dangers, enhancing our sense of taste, and evoking emotions and memories.

28 Apr 2026

Experts establish new clinical trial endpoints for oligometastatic cancer

An international group of experts led by the Comprehensive Cancer Centre (CCC) at MedUni Vienna and University Hospital Vienna has established endpoints for clinical trials in patients with cancer and isolated metastases.

28 Apr 2026

NCCN publishes new patient guide for prostate cancer screening

The National Comprehensive Cancer Network® (NCCN®)-an alliance of leading cancer centers-has published a new book explaining the latest evidence and expert recommendations around prostate cancer screening.

28 Apr 2026

Electroacupuncture promotes weight loss by turning white fat into brown

Globally rising obesity rates pose major health risks, including type 2 diabetes, cardiovascular disease, and certain malignancies.

28 Apr 2026

Study identifies protein essential for repairing damage after inflammation

Whenever there is a wound or infection, the body produces an inflammatory response. This is the body's first line of defense, and macrophages — cells of the innate immune system — play a key role: first, they help eliminate pathogens and other infectious agents, and then they trigger the mechanisms that repair the damage caused during the inflammatory process.

28 Apr 2026