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Osteoprotegerin links bone metabolism to cardiovascular disease

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Osteoprotegerin (OPG), a glycoprotein in the tumor necrosis factor superfamily, regulates bone metabolism by suppressing the formation and activation of osteoclasts.

13 Feb 2026

Novel antibody 007 targets the elusive HIV envelope epitope

HIV-1 can be neutralized by antibodies which bind to vulnerable structures on the virus surface. One such vulnerable site is the so-called V3 glycan site of the viral envelope protein.

13 Feb 2026

New AI framework enables reliable intracellular antibody design

A new artificial intelligence-driven pipeline developed in a collaborative research combines protein structure prediction, sequence design, and live-cell screening together to enable rapid conversion of antibody sequences into functional intracellular antibodies (intrabodies) that are stable within living cells.

13 Feb 2026

NHS updates bladder cancer chemotherapy guidelines

Hundreds of people with advanced bladder cancer across the UK can now receive three rather than six chemotherapy cycles following research by Queen Mary University of London which has led to a change to NHS treatment guidelines.

13 Feb 2026

Parkinson's-related weight loss reflects a failure of the body's energy-producing pathways

Weight loss is a well-recognized but poorly understood non-motor feature of Parkinson's disease (PD). Many patients progressively lose weight as the disease advances, often alongside worsening motor symptoms and quality of life.

13 Feb 2026

Exercise-induced activation of neurons mediates improvements in endurance

Exercise does more than strengthen muscles; it also rewires the brain. In a study publishing February 12 in the Cell Press journal Neuron, researchers reveal that the lasting gain in endurance from repeated exercise-such as the ability to run farther and faster over time-involves changes in brain activity that help muscles and hearts to become stronger.

13 Feb 2026

Genetic variants in 11 regions of human genome influence the gut microbiome

In two new studies on 28,000 individuals, researchers are able to show that genetic variants in 11 regions of the human genome have a clear influence on which bacteria are in the gut and what they do there.

13 Feb 2026

How psychedelics alter perception: A glimpse into the brain's inner world

Research findings reinforce new approaches in psychology, using psychedelic substances under medical supervision to treat certain clinical conditions.

13 Feb 2026

Study reveals insights into how cells coordinate gene compensation response

Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms.

12 Feb 2026

Study reveals dynamic nature of myelin swellings

An international research team of Amsterdam UMC, VU LaserLab, the Netherlands Institute for Neuroscience and the University of Edinburgh have gained new insights into the dynamics of myelin swellings in the brain.

12 Feb 2026

Distinct microbial signature identified in pediatric Crohn's disease

NYU researchers have found a "microbial signature" of pediatric Crohn's disease that differs from the makeup of gut bacteria in children with other gastrointestinal conditions, with Crohn's patients harboring more pro-inflammatory bacteria and less protective bacteria.

12 Feb 2026

New strategy may improve ovarian cancer treatment outcomes

A new study published by Mayo Clinic researchers suggests that ovarian cancer cells quickly activate a survival response after PARP inhibitor treatment, and blocking this early response may make this class of drugs work better.

12 Feb 2026

Study examines the relationship between leukocyte telomere length and age-related cataract

Cataracts remain the leading cause of blindness worldwide among adults over 50, despite major advances in surgical treatment.

12 Feb 2026

AI system controls brain circuits during social behavior

A male fruit fly in a laboratory chamber extends his wings and vibrates them to produce his species' version of a love song.

12 Feb 2026

Novel DAMP markers advance myocardial contusion detection

Researchers are exploring a new generation of biochemical markers that may help clinicians detect myocardial contusion. A frequently overlooked form of heart injury caused by blunt chest trauma, earlier and more accurately.

12 Feb 2026

Brain circuit links past experiences to appetite control

Our past experiences shape how much we eat and where and what we choose to eat. Using preclinical models, researchers from Mass General Brigham and the Broad Institute of MIT and Harvard have identified brain cells that translate contextual information into appetite control.

12 Feb 2026

Light-based sensor can detect low concentrations of cancer biomarkers in the blood

Researchers have developed a highly sensitive light-based sensor that can detect extremely low concentrations of cancer biomarkers in the blood.

12 Feb 2026

Study highlights key role of non-contractile cardiac cells in persistent atrial fibrillation

Atrial fibrillation (AF), the most common chronic cardiac arrhythmia in clinical practice, is very challenging to treat once it becomes persistent, after which spontaneous return to normal rhythm becomes highly unlikely.

12 Feb 2026

Boosting good immune cells can help fight insulin resistance and diabetes

Scientists at the University of Pittsburgh School of Medicine discovered a surprising new way the body can fight insulin resistance and diabetes – by boosting a special type of "good" immune cell in fat tissue.

12 Feb 2026

Early cognitive stimulation preserves memory in Alzheimer’s

A team from the Institute of Neurosciences of the University of Barcelona (UBneuro) has discovered that early and sustained cognitive stimulation can help preserve brain connectivity and memory in Alzheimer's disease, even in advanced stages of the pathology.

12 Feb 2026