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Researchers discover new biomarker of "complicated" mild- to severe-pediatric traumatic brain injury

Researchers at the University of Pittsburgh and UPMC Children's Hospital of Pittsburgh discovered a promising new biomarker of "complicated" mild- to severe-pediatric traumatic brain injury, or TBI.

9 Dec 2025

SIRT3 deficiency worsens eustachian tube dysfunction during middle-ear infection

Middle-ear infections caused by Gram-negative bacteria remain among the most common pediatric illnesses worldwide.

9 Dec 2025

Blinking suppression reveals how the brain filters speech in noisy environments

Blinking is a human reflex most often performed without thinking, like breathing. Although research on blinking is usually related to vision, a new Concordia study examines how blinking is connected to cognitive function such as filtering out background noise to focus on what someone is trying to say to us in a crowded room.

9 Dec 2025

Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

This study shows that vacancy-engineered MoS₂ nanoflowers drive mitochondrial biogenesis in human mesenchymal stem cells by activating SIRT1–PGC-1α signaling and reducing oxidative stress. These treated cells transfer more functional mitochondria to injured recipient cells, restoring energy metabolism and redox balance in multiple in vitro models.

9 Dec 2025

Mammary glands of domesticated livestock and humans could harbor avian influenza

An ongoing outbreak of highly pathogenic avian influenza has affected more than 184 million domestic poultry since 2022 and, since making the leap to dairy cattle in spring 2024, more than 1,000 milking cow herds.

9 Dec 2025

Genetic risk score can guide early screening for type 1 diabetes

A test using genetics to predict who is at the highest risk of developing type 1 diabetes could one day be applied to largescale health studies, to identify adults who could benefit from new drugs, new research shows.

9 Dec 2025

Gut microbe metabolite TMA improves blood sugar by shutting down a key inflammatory switch

Researchers identified trimethylamine (TMA) as a gut microbe–derived metabolite that directly inhibits IRAK4 to reduce metabolic inflammation and improve glycaemic control in high-fat-diet-fed mice. Choline-driven increases in TMA production replicated these benefits, revealing a host–microbe signaling axis with therapeutic potential for obesity-associated insulin resistance.

9 Dec 2025

Study explains why mpox cases can appear weeks after exposure

Mpox virus clade Ib shows a longer and more variable incubation period than previously characterized clades, with symptom onset extending well beyond 21 days in a substantial minority of cases. Incubation varies by transmission route, with shorter intervals after sexual exposure and longer periods following nonsexual community transmission, raising implications for surveillance and postexposure guidance.

9 Dec 2025

A massive mid-14th-century volcanic eruption likely triggered the spread of the "Black Death"

A large volcanic eruption or cluster of eruptions in the mid-1340s triggered severe climate anomalies that drove harvest failures across parts of Europe. These shocks reshaped Mediterranean grain trade routes, likely introducing plague-infected fleas into Italian ports and helping ignite the Black Death.

9 Dec 2025

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein long considered impossible to target with drugs - a discovery that could open the door to a new class of treatments for leukemia and other hard-to-treat cancers.

9 Dec 2025

WSU researchers discover how a neural circuit drives relapse after opioid use

Washington State University researchers have discovered how a neural circuit – or a connection between two brain regions – drives relapse after opioid use, a finding that could lead to more effective treatments for opioid use disorders.

9 Dec 2025

Brain function discovery helps explain why childhood adversity raises metabolic disease risk in women

McGill University researchers have identified a brain function that helps explain why childhood stress raises metabolic health risks for some women later in life.

9 Dec 2025

Study uncovers how the body's bile acids bind to block C. diff's most dangerous toxin

In a major step towards a precision therapy for Clostridioides difficile (C. diff) infection, researchers at The Hospital for Sick Children (SickKids) have uncovered how the body's bile acids bind to block C. diff's most dangerous toxin.

9 Dec 2025

Dietary restriction reprograms cancer-fighting immune cells to enhance anti-tumour immunity

Reducing calorie intake helps cancer-fighting immune cells do their jobs more effectively, reports a study by Van Andel Institute scientists and collaborators.

9 Dec 2025

New antibody shows ability to overcome treatment resistance in blood cancers and solid tumors

In a new preclinical study, researchers from The University of Texas MD Anderson Cancer Center developed an antibody therapy called 77A that showed an ability to overcome treatment resistance in blood cancers, such as myeloma and lymphoma, as well as solid tumors.

9 Dec 2025

Patients receiving T-cell redirecting therapies can safely be monitored at home

Patients who receive T-cell redirecting therapies are typically hospitalized for several days after treatment to watch for side effects.

9 Dec 2025

Accuracy of remote photoplethysmography drops sharply at elevated heart rates

Researchers at Bielefeld University have analyzed how reliably AI methods can detect pulse rates from simple video recordings.

9 Dec 2025

Online reference library provides a more accurate picture of drug exposure

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete.

9 Dec 2025

Study reveals how brain protein KCC2 influences reward learning

A new finding from researchers at Georgetown University Medical Center shows that the learning process of associating cues with rewards can be altered by increased or decreased activity of a specific protein in the brain.

9 Dec 2025

Supportive marriages may shape appetite control through oxytocin and the brain–gut axis

Supportive marital relationships are associated with lower BMI, fewer food addiction symptoms, higher oxytocin, stronger frontal brain responses to food cues, and favorable gut tryptophan metabolites. These coordinated social, neural, hormonal, and gut pathways suggest a plausible biological link between emotional support and healthier eating regulation.

8 Dec 2025

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Medical Science News

Researchers discover new biomarker of "complicated" mild- to severe-pediatric traumatic brain injury

SIRT3 deficiency worsens eustachian tube dysfunction during middle-ear infection

Blinking suppression reveals how the brain filters speech in noisy environments

Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

Mammary glands of domesticated livestock and humans could harbor avian influenza

Genetic risk score can guide early screening for type 1 diabetes

Gut microbe metabolite TMA improves blood sugar by shutting down a key inflammatory switch

Study explains why mpox cases can appear weeks after exposure

A massive mid-14th-century volcanic eruption likely triggered the spread of the "Black Death"

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

WSU researchers discover how a neural circuit drives relapse after opioid use

Brain function discovery helps explain why childhood adversity raises metabolic disease risk in women

Study uncovers how the body's bile acids bind to block C. diff's most dangerous toxin

Dietary restriction reprograms cancer-fighting immune cells to enhance anti-tumour immunity

New antibody shows ability to overcome treatment resistance in blood cancers and solid tumors

Patients receiving T-cell redirecting therapies can safely be monitored at home

Accuracy of remote photoplethysmography drops sharply at elevated heart rates

Online reference library provides a more accurate picture of drug exposure

Study reveals how brain protein KCC2 influences reward learning

Supportive marriages may shape appetite control through oxytocin and the brain–gut axis

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Extending the reach of Amperia™

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