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Sponge and sea slug partnership yields a new anticancer molecule with drug design promise

Researchers identified jorumycidine, a new hexacyclic marine alkaloid from the nudibranch Jorunna funebris and its dietary sponge, Haliclona sp., and demonstrated that it exhibits potent nanomolar cytotoxicity against multiple myeloma cells. They also proposed a new biosynthetic route involving cross-species metabolic interplay and an unusual oxazolidine ring that may help stabilize a pharmacologically important scaffold.

8 Apr 2026

Cola may quickly lower pH inside orthodontic clear aligners and shift oral bacteria within hours

Researchers found that cola exposure quickly lowered pH and altered the microbiome on the inner surface of clear aligners, with the greatest disruption observed when aligners were removed before drinking and then reinserted. In this small 24-hour study, wearing aligners during exposure appeared less disruptive than removing them, though the authors said the mechanism still needs further study.

8 Apr 2026

Why early-onset cancers are rising and how researchers plan to stop them

Early-onset cancers are rising worldwide, and this Cell Perspective argues that cancer prevention must move beyond static risk-factor snapshots toward life-course exposure mapping, tissue-level biology, and dynamic estimates of preventability. The authors propose three linked frameworks to speed discovery of cancer causes and translate those findings into more precise prevention and interception strategies.

8 Apr 2026

Study reveals how tau tangles spread from one brain region to another in Alzheimer's

Alzheimer's disease is a progressive neurodegenerative disorder that slowly impairs memory, affects thinking skills, and eventually interferes with daily functioning.

8 Apr 2026

New MRI method tracks transplanted heart stem cells for months

Researchers at the Institute of Biomedical Engineering at the University of Toronto have demonstrated a new way to monitor transplanted stem-cell-derived heart cells using magnetic resonance imaging (MRI).

8 Apr 2026

Yale researchers use zebrafish to find precision treatments for autism

In recent decades, the zebrafish has become one of the most valuable model organisms in scientific research.

8 Apr 2026

Study finds genetic basis for GLP-1 weight loss efficacy and side effects

23andMe Research Institute, a nonprofit medical research organization, announced the publication of a study that identifies genetic predictors for GLP-1 weight loss efficacy and side effects.

8 Apr 2026

New clinical guidelines address blood clot prevention in pediatric patients

The American Society of Hematology (ASH) and the International Society on Thrombosis and Haemostasis (ISTH) released comprehensive clinical practice guidelines on anticoagulant prophylaxis in non-cardiac pediatric patients at risk of venous thromboembolism (VTE).

8 Apr 2026

Study identifies a common brain activity pattern across psychedelics

Scientists have demonstrated, for the first time, that several psychedelic drugs – including psilocybin, LSD, mescaline, DMT and ayahuasca – produce a common pattern of brain activity despite their distinct chemistries.

8 Apr 2026

Clusterin inhibition offers new hope for treating cervical gastric-type adenocarcinoma

Gastric-type adenocarcinoma (GAS) is one of the most aggressive non-human papillomavirus (HPV)-associated cervical adenocarcinomas and remains especially difficult to diagnose and treat.

8 Apr 2026

Future CAR therapy expands beyond T cells to treat diverse diseases

CAR-T therapy has transformed treatment for some blood cancers, with seven FDA-approved products and strong clinical responses in hematologic malignancies.

8 Apr 2026

High affinity for immune receptors predicts antibody drug associated anaphylaxis risk

Antibody therapeutics are laboratory-made proteins designed to work like the body's natural antibodies. They are widely used to treat diseases such as cancer by binding to specific targets, including cancer cells or inflammatory molecules.

8 Apr 2026

CIPHER-seq technology reveals how immune cells communicate during treatment

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

8 Apr 2026

Extended work shifts disrupt normal cortisol patterns in female nurses

Levels of cortisol, often referred to as the "stress hormone," typically peak in the early morning hours, preparing the body for the day's challenges by increasing alertness and energy levels, and gradually decline throughout the day, reaching their lowest point around midnight.

8 Apr 2026

XPANCEO unveils passive eye tracking using smart contact lenses

XPANCEO, a deep-tech company developing smart contact lens, has unveiled a passive eye-tracking system that achieves industry-level measurement precision using standard cameras.

8 Apr 2026

New guidelines and follow-up standards improve pulmonary embolism outcomes

Pulmonary embolism, or PE, is a serious and sometimes life-threatening condition that occurs when a blood clot travels to the lungs and blocks blood flow.

8 Apr 2026

Sugar intake may reduce effectiveness of relaxation exercises

How does sugar affect relaxation exercises? A new study carried out by researchers from the University of Konstanz provides revealing insights into the connection between blood glucose and the autonomic nervous system: The intake of sugar counteracts relaxation.

7 Apr 2026

Gut microbiota regulates intestinal epithelial cell function and plasticity

A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and intestinal cells.

7 Apr 2026

Noninvasive urine test improves prediction of bladder cancer treatment outcomes

Bladder cancer arises from the lining of the bladder, the organ that stores urine, and is one of the most common cancers in the United States. Most patients are diagnosed at an early stage called non-muscle invasive bladder cancer (NMIBC), in which the tumors are confined to the inner layers of the bladder.

7 Apr 2026

Brain study reveals sender and receiver roles in default mode network

The default mode network (DMN) is a distributed set of interconnected brain regions that has long been associated with internally oriented cognition such as remembering the past, thinking about the future, or thinking about oneself.

7 Apr 2026