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Research reveals how Regnase-1 deficiency enhances NK cell tumor killing

Natural killer (NK) cells play a crucial role in the first line of host defense by eliminating bacteria, viruses, and mutated cells that might become cancer cells.

30 May 2024

Coupling bacteria-laden hydrogel and electronics for adaptive treatment of skin inflammation

Coupling skin bacteria-laden hydrogel and electronics, researchers have introduced the ABLE platform, a bioelectronics system that can deliver management and adaptive treatment of skin inflammation.

30 May 2024

Unveiling the epigenetic impact of prenatal amphetamine exposure using C. elegans models

Amphetamine is a psychostimulant that has been used to treat a variety of brain dysfunctions. However, it is a highly abused drug.

30 May 2024

Cervix-on-a-Chip: A breakthrough model for studying women's health

Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women's health and affects more than 25% of reproductive-aged women.

30 May 2024

Engineered immunogens show promise in inducing HIV broadly neutralizing antibodies

Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals' immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs).

30 May 2024

Targeting Ctdnep1: A potential therapeutic approach to combat bone loss

Osteoporosis, a condition characterized by porous and fragile bones, poses a significant threat to skeletal health.

30 May 2024

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Aging-related physiological decline and the accumulation of senescent or aging cells in bodily tissues can trigger a number of diseases.

30 May 2024

Mast cells and PGE2: Key players in controlling asthma inflammation

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma attack, inducing symptoms such as trouble breathing and narrowing of the airways.

30 May 2024

Newly discovered lincRNA controls the development and function of regulatory T cells

The T cells in our blood fight against cancer, viruses and bacteria. Specific regulatory T cells are required to control faulty immune responses, and disruption in their function may lead to autoimmune diseases or cancer.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Study finds distinct link between sleep duration, social media usage, and brain activation in teens

A new study to be presented at the SLEEP 2024 annual meeting found a distinct relationship between sleep duration, social media usage, and brain activation across brain regions that are key for executive control and reward processing.

30 May 2024

Statins may block an inflammation pathway involved in the development of cancer

A new study led by investigators from Mass General Cancer Center, a founding member of the Mass General Brigham healthcare system, reveals that statins-;commonly used cholesterol-lowering drugs-;may block a particular pathway involved in the development of cancer that results from chronic inflammation.

30 May 2024

RCSI and Head Diagnostics collaborate to revolutionize multiple sclerosis assessment

RCSI has partnered with Head Diagnostics (Dublin, Ireland) on a clinical study to enhance the assessment and monitoring of Multiple Sclerosis (MS) through innovative technology.

30 May 2024

Innovative startups leading the charge in alternative proteins to solve global food crisis

A recent review in Nature Communications highlights the crucial role of innovative startups in advancing alternative protein sources to tackle global food security challenges and translate these efforts into commercial applications.

29 May 2024

Could edible robots be the future of food and medicine?

A review in Nature Reviews Materials explores the potential of edible materials in creating robotic foods and edible robots, highlighting their therapeutic and environmental benefits, while addressing current research challenges.

29 May 2024

New weapon against cancer: "DNA warhead" targets mutant protein in tumor cells

Tumor protein P53 (TP53) plays an important role in suppressing the growth of tumors. Mutations in the gene for TP53 can have a disastrous effect, hampering the body's ability to fight tumors and even encouraging their growth.

29 May 2024

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

A recent review in Signal Transduction and Targeted Therapy highlights the role of exercise-induced molecules, exerkines, in disease prevention and treatment, emphasizing their molecular mechanisms and therapeutic potential.

29 May 2024

Opioid receptors play unexpected role in gut nervous system development

Researchers at Rice University have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the "brain in the gut."

29 May 2024

New antibody shows promise as universal weapon against COVID-19 variants

SARS-CoV-2, the virus that causes COVID-19 disease, continues to evolve and evade current vaccine and therapeutic interventions.

29 May 2024

Transparent skull implant unveils new frontiers in brain imaging

In the first study of its kind, researchers from the Keck School of Medicine of USC and the California Institute of Technology (Caltech) designed and implanted a transparent window in the skull of a patient, then used functional ultrasound imaging (fUSI) to collect high-resolution brain imaging data through the window.

29 May 2024