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Weak brain circuit connection found to influence overeating and obesity

Why can some people easily stop eating when they are full and others can't, which can lead to obesity?

16 May 2024

Novel gene-delivery vehicle shows promise for treating brain disorders

In an important step toward more effective gene therapies for brain diseases, researchers from the Broad Institute of MIT and Harvard have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein.

16 May 2024

Genes and age reveal new insights into cognitive variability, study finds

Study examines the effects of specific genes and age on cognition, revealing potential for creating genotype- and cognition-stratified cohorts for future research.

16 May 2024

Hunting dogs in Washington show antibodies to H5N1 bird flu virus, study finds

Study found antibodies to H5 and N1 subtype influenza A viruses in 2% of hunting dogs in Washington, suggesting potential transmission from waterfowl to dogs.

16 May 2024

SMART researchers identify key mechanism behind artemisinin resistance in malaria

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), Columbia University Irving Medical Center (CUIMC), and Nanyang Technological University, Singapore (NTU Singapore), have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs – specifically artemisinin (ART) – through a cellular process called transfer Ribonucleic acid (tRNA) modification.

16 May 2024

Researchers develop pathoblockers to combat bacterial pneumonia toxins

In most cases, antibiotics are a reliable form of protection against bacterial infections. They have saved billions of human lives since their introduction.

16 May 2024

Global initiative REACT targets early detection of atherosclerosis

One in three people around the world die from cardiovascular disease, which is mainly caused by atherosclerosis.

16 May 2024

Liquid biopsy biomarker predicts melanoma therapy response

If black skin cancer (melanoma) spreads, there are various therapies that can be used. However, there is still insufficient research into who responds to which therapy and whether resistance may develop over time.

16 May 2024

TRPS1 could serve as a new target for drugs against breast cancer

The mammary gland is a complex tissue comprising a variety of cell types. Their proper functioning is crucial for the health of the breast.

16 May 2024

Study demonstrates link between disrupted developmental dopamine signaling and ASD

Recent evidence suggests that dopamine plays a crucial role in neural development. In a novel study, investigators demonstrated the link between disrupted developmental dopamine signaling and autism spectrum disorder (ASD).

16 May 2024

New therapy shows greater weight loss in mice by targeting brain's appetite center

A groundbreaking paper in Nature describes a promising new therapy for obesity that leads to greater weight loss in mice than existing medications.

16 May 2024

New guideline issued for antiseizure medication use in pregnant epilepsy patients

A new guideline has been issued to help neurologists and other clinicians determine the best antiseizure medications for people with epilepsy who may become pregnant.

16 May 2024

Repurposing human-approved drugs for prion disease treatment

Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.

16 May 2024

Unveiling the role of neutrophils in lung cancer progression

Lung cancer remains a leading global health concern, responsible for the highest number of cancer-related deaths worldwide.

16 May 2024

Mechanistic insights into the role of huc-mscs in treating acute liver failure

Acute liver failure (ALF) is a life-threatening clinical problem with limited treatment options. Administration of human umbilical cord mesenchymal stem cells (hUC-MSCs) may be a promising approach for ALF.

16 May 2024

Clinical trial suggests hypertension self-management strategies may be effective to control blood pressure

The study findings suggest that self-management strategies for hypertension may effectively reduce blood pressure levels over 24 months without increasing healthcare resource utilization or adverse events as compared to usual care.

16 May 2024

Does discrimination cause harm to the body?

Researchers investigate whether experiencing discrimination is associated with accelerated biological processes of aging.

16 May 2024

Cervical cancer rates drop significantly among vaccinated women

The efficiency of the HPV vaccination program in reducing the prevalence of cervical cancers.

16 May 2024

Gut microbiota and obesity: New study shows promising results with probiotic and prebiotic intervention

The effect of a low-calorie, sufficient fiber regimen combined with probiotic supplements and physical activity on health, body composition, and physique.

16 May 2024

New study uncovers 17 genes driving clonal hematopoiesis and links to aging and disease

Researchers identified 17 new genes positively selected for clonal hematopoiesis in a large U.K. Biobank cohort, revealing their impact on aging and disease risks.

15 May 2024