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Scientists uncover rare gene variants that help people live past 100

Researchers studying over 2,000 Ashkenazi Jewish centenarians uncovered two rare IGF-1 gene variants linked to exceptional longevity. These variants reduce IGF-1 receptor activity through either diminished receptor binding or lower circulating IGF-1 levels.

26 Mar 2025

This molecule links your diet to stroke and Alzheimer’s—here’s how to stop it

A new review explores how TMAO, a gut-derived metabolite from red meat and other foods, contributes to heart and brain diseases. It also highlights promising interventions—like plant-based diets, probiotics, and nutraceuticals—to lower TMAO levels and reduce health risks.

26 Mar 2025

Flavonoids help regulate gut hormones and show promise in managing type 2 diabetes

Flavonoids show promise in treating type 2 diabetes mellitus by targeting the enteroendocrine system and regulating key gut hormones. They enhance insulin sensitivity, reduce oxidative stress, and influence appetite, glucose uptake, and hormone secretion.

26 Mar 2025

Scientists link emulsifiers in processed foods to allergy and immune disorders

Review identifies common food additives in ultra-processed foods—particularly emulsifiers like carrageenan and polysorbate 80—as key drivers of gut dysbiosis, inflammation, and allergic diseases by disrupting intestinal barriers and activating proinflammatory pathways.

26 Mar 2025

Discovery provides crucial molecular targets for future obesity treatments

The pleasure we get from eating junk food - the dopamine rush from crunching down on salty, greasy French fries and a luscious burger - is often blamed as the cause of overeating and rising obesity rates in our society.

26 Mar 2025

Researchers identify key gene linked to heroin addiction

Opioid use disorder is associated with more than 350,000 deaths annually worldwide. Guided by the need for an increased understanding of critical neurobiological features of addiction, researchers have now found a unique molecular signature and genes in the orbitofrontal cortex associated with heroin-seeking behavior.

26 Mar 2025

Study highlights the flexible nature of numerical quantity processing in the brain

The National Institute of Information and Communications Technology (NICT, President: TOKUDA Hideyuki, Ph.D.) has revealed, through fMRI-based brain activity analysis, that multiple regions in the human cerebral cortex flexibly represent numerical quantity.

26 Mar 2025

Addressing cardiovascular risk factors in emerging adulthood

Many teenagers enter adulthood with significant risk factors for cardiovascular disease, and the transition from adolescence to adulthood is a key time to address these risk factors and reduce the risk of developing future cardiovascular disease, according to a new American Heart Association scientific statement published today in the Journal of the American Heart Association.

26 Mar 2025

Understanding how the brain processes positive and negative stimuli

Researchers analyzed mice's D1 and D2 neurons to understand how they code and respond to appetitive and aversive stimuli.

26 Mar 2025

COVID-19 vaccines may cut risk of long COVID

Full COVID-19 vaccination may reduce post-COVID-19 condition risk by 27%, though more research is needed, especially for children and immunocompromised groups.

26 Mar 2025

AI is as good as pathologists at diagnosing coeliac disease, study finds

A machine learning algorithm developed by Cambridge scientists was able to correctly identify in 97 cases out of 100 whether or not an individual had coeliac disease based on their biopsy, new research has shown.

26 Mar 2025

TikTok fuels ADHD self-diagnosis with misleading content, study shows

Psychologists find most TikTok videos about ADHD to be misleading, often overgeneralizing normal behaviors as symptoms. These videos shape young adults’ perceptions and contribute to rising self-diagnosis trends.

25 Mar 2025

Study shows red wine biomarkers in urine can predict inflammation levels

Researchers found that specific metabolites of resveratrol in urine accurately reflect red wine consumption. These biomarkers were linked to reduced inflammation in older adults at cardiovascular risk, unlike traditional food surveys.

25 Mar 2025

Epigenetic scores offer new insights into cardiometabolic disease prevention

A new study explores how epigenetic markers-chemical modifications that influence gene activity-can help predict the risk of developing cardiometabolic diseases and guide personalized prevention strategies.

25 Mar 2025

Study reveals distinct infection strategies of Zika and dengue viruses

Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host's dendritic cells.

25 Mar 2025

Arthritis drug shows promise in halting seizures in mice with epilepsy

A drug typically prescribed for arthritis halts brain-damaging seizures in mice that have a condition like epilepsy, according to researchers at the University of Wisconsin–Madison.

25 Mar 2025

New research sheds light on CDK7's role in cancer cell proliferation

For organs to develop, grow and regenerate, cells must proliferate. But when that process goes awry, leading to uncontrolled cell growth, cancer can emerge.

25 Mar 2025

Why Mānuka isn't the only healing honey from New Zealand anymore

New research from Auckland University of Technology reveals that eight native New Zealand honeys, beyond mānuka, possess unique antioxidant, antibacterial, and bioactive properties. Thyme and beech honeydew stood out for their vitamin C and polyphenol content.

25 Mar 2025

Stanford study reveals glucose's surprising role in cell differentiation

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process by which stem cells give rise to specialized cells that make up all the body's tissues.

25 Mar 2025

Multi-modal imaging reveals complex brain alterations associated with autism spectrum disorder

Autism spectrum disorder (ASD) is a growing global concern, affecting approximately 2.8% of children in the United States and 0.7% in China. ASD is characterized by challenges in social interaction, communication difficulties, and repetitive behaviors, making early diagnosis critical for improving outcomes.

25 Mar 2025