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Researchers discover how "leaky" mitochondria can drive harmful inflammation

Researchers have discovered how "leaky" mitochondria – the powerhouses of our cells – can drive harmful inflammation responsible for diseases such as lupus and rheumatoid arthritis.

4 Mar 2024

How long do cognitive and memory dysfunctions persist after SARS-CoV-2 infection?

Whether cognitive deficits can be measured after severe acute respiratory syndrome (SARS-CoV-2) infection.

4 Mar 2024

PharmaKure partners with Sheffield Hallam University to develop epigenetic markers for Alzheimer’s disease prediction

PharmaKure, a clinical stage pharmaceutical company developing precision medicines for Alzheimer’s Disease (AD) and other neurodegenerative diseases, today announces a new epigenetics collaboration with Sheffield Hallam University.

4 Mar 2024

The impact of quinoa bioactive compounds on gut health

Researchers review the beneficial impacts of quinoa and its bioactive compounds, particularly its effects on intestinal microflora.

4 Mar 2024

How live music directly stimulates the affective brain, emotionally engaging listeners in real time

Researchers explore how live and recorded music stimulates the brain.

4 Mar 2024

Prioritizing biologically motivated approaches in Mendelian randomization studies

Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease.

1 Mar 2024

Microbial signatures linked to immunotherapy response across cancers

The microbiome can identify those who benefit from combination immunotherapy across multiple different cancers, including rare gynecological cancers, biliary tract cancers and melanoma.

1 Mar 2024

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel genetic arrangement that may help a common bacterium in the human gut, Bacteroides fragilis, protect itself from tetracycline, a widely used antibiotic.

1 Mar 2024

Exploring the epigenetic impact of smoking across racial and ethnic groups

Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses.

1 Mar 2024

Unlocking the secrets of T follicular helper cells for better treatment strategies

T follicular helper cells (Tfh) are essential for strong antibody-mediated reactions of our immune system during infections and vaccinations. However, if they get out of control, this can cause diseases such as autoimmunity, allergies or cancer.

1 Mar 2024

Nerve overgrowth identified as cause of pain in recurring UTIs

A perplexing problem for people with recurring urinary tract infections (UTIs) is persistent pain, even after antibiotics have successfully cleared the bacteria.

1 Mar 2024

Unraveling the complex cellular composition of aldosterone-producing adenomas

Researchers from Tokyo Medical and Dental University (TMDU) find that the cells that make up aldosterone-producing adenomas become more transcriptionally active and express higher levels of genes linked to hormone production over intratumoral differentiation.

1 Mar 2024

Broad-spectrum neutralizing antibody mAb-39 targets conserved S2 epitope in SARS-CoV-2

The ongoing COVID-19 pandemic caused by SARS-CoV-2 has caused serious damage to public health and the global economy, and one strategy to combat COVID-19 has been the development of broadly neutralizing antibodies for prophylactic and therapeutic use.

1 Mar 2024

Unlocking the molecular mysteries of autism and intellectual disability

A new study from a team of McGill University and Vanderbilt University researchers is shedding light on our understanding of the molecular origins of some forms of autism and intellectual disability.

1 Mar 2024

Penn engineers develop targeted lung delivery system using lipid nanoparticles

Penn Engineers have developed a new means of targeting the lungs with lipid nanoparticles (LNPs), the miniscule capsules used by the Moderna and Pfizer-BioNTech COVID-19 vaccines to deliver mRNA, opening the door to novel treatments for pulmonary diseases like cystic fibrosis.

1 Mar 2024