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Study uncovers the anti-aging role of vitamin D and vitamin D receptor in Drosophila midgut model

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "The anti-aging effect of vitamin D and vitamin D receptor in Drosophila midgut."

27 Feb 2024

FB1006: AI-discovered drug advances to clinical trials for ALS treatment

Amyotrophic Lateral Sclerosis (ALS) is a fatal type of motor neuron disease characterized by progressive degeneration of nerve cells in the spinal cord and brain, resulting in muscle weakness and paralysis that can include the inability to walk and speak, or even swallow and breathe.

27 Feb 2024

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology, has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.

27 Feb 2024

Hedonic overdrive model best explains high-fat diet-induced obesity in mice

High-fat diets cause obesity in male mice. The underlying mechanism, however, remains controversial. After assessing three contrasting ideas, researchers have determined that the hedonic overdrive model provides the best fit, according to a new study published in the journal Obesity, The Obesity Society's (TOS) flagship journal.

27 Feb 2024

Bio-Rad launches vericheck ddPCR replication competent lentivirus and replication competent AAV kits for cell and gene therapy production

Rapid, Sensitive, and Validated Detection of Viral Replication Genes Using Droplet Digital™ PCR During Cell and Gene Therapy Production.

From Bio-Rad Laboratories 27 Feb 2024

Optibrium launches a metabolism prediction software platform tailored to DMPK scientists

Semeta™ offers high sensitivity and superior precision for the prediction of Phase I and II metabolic routes, sites, products and liabilities in early drug discove.ry

From Optibrium Ltd. 27 Feb 2024

Smartphone addiction fuels loneliness and reduces well-being, study finds

How loneliness mediates the link between excessive smartphone use or addiction.

27 Feb 2024

Mapping the brain: How cell types and location influence Parkinson’s disease

A single-cell spatial transcriptome analysis on murine brain expression in age and disease using a Parkinson's disease.

27 Feb 2024

Better cognition and academic performance are associated with Mediterranean diet adherence

The relationship between various Mediterranean-style eating patterns and cognitive and academic performance.

27 Feb 2024

UMSOM wins $3.5 million BARDA contract to develop animals models for radiation research

University of Maryland School of Medicine Dean Mark T. Gladwin, MD, announced today that UMSOM faculty scientists have been selected as key contractors by the Biomedical Advanced Research and Development Authority (BARDA), for the federal agency's Radiation Nuclear Animal Model Development program.

26 Feb 2024

Research unveils major discovery in gut-brain axis communication

The mechanisms by which antidepressants and other emotion-focused medications work could be reconsidered due to an important new breakthrough in the understanding of how the gut communicates with the brain.

26 Feb 2024

Revolutionizing microscopy with affordable high-resolution techniques

Researchers at the University of Illinois at Urbana-Champaign have shown for the first time that expensive aberration-corrected microscopes are no longer required to achieve record-breaking microscopic resolution.

26 Feb 2024

Croatian sea fennel may contain a treasure trove of preservative and anti-aging metabolites

A study in Foods journal finds that Croatian sea fennel's essential oils and hydrolats exhibit significant anti-aging potential, differing chemically and functionally from French sea fennel, suggesting unique cosmetic applications.

26 Feb 2024

Boston College biologist wins NIH grant to study viral insulins for cancer treatment

Boston College Assistant Professor of Biology Emrah Altindis has been awarded a five-year, $2.5-million grant from the National Institutes of Health to study viral insulins and mechanisms related to IGF-1 receptor protein inhibition and its potential applications in cancer treatment.

26 Feb 2024

New clinical practice guideline offers evidence-based recommendations for managing inhalant allergies with immunotherapy

The American Academy of Otolaryngology–Head and Neck Surgery Foundation published the Clinical Practice Guideline: Immunotherapy for Inhalant Allergy today in Otolaryngology–Head and Neck Surgery.

26 Feb 2024

Breakthrough research unveils β-cell dynamics in Type 1 diabetes

About eight million people live with Type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced "beta") in the pancreas, leading to a lack of insulin and inability to regulate blood sugar.

26 Feb 2024

Study reveals BCG vaccine's unexpected role in fighting influenza

As Canada's flu season collides with record strep A cases and ongoing COVID-19 concerns, a new study is shedding light on our understanding of respiratory immune responses.

26 Feb 2024

Gut bacteria may be responsible for sight loss in certain inherited eye diseases

Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher.

26 Feb 2024

Understanding obesity's effects on liver metabolism

Your liver plays a vital role in your metabolism, the biological process which converts food into energy.

26 Feb 2024

Insights into gut plasticity mechanisms unveiled through fruit fly research

One of the most striking examples of gut plasticity can be observed in animals that are exposed to prolonged periods of fasting, such as hibernating animals or phyton snakes that goes for months without eating, where the gut shrinks with as much as 50%, but recovers in size following a few days of re-feeding.

26 Feb 2024

Medical Science News

Study uncovers the anti-aging role of vitamin D and vitamin D receptor in Drosophila midgut model

FB1006: AI-discovered drug advances to clinical trials for ALS treatment

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

Hedonic overdrive model best explains high-fat diet-induced obesity in mice

Bio-Rad launches vericheck ddPCR replication competent lentivirus and replication competent AAV kits for cell and gene therapy production

Optibrium launches a metabolism prediction software platform tailored to DMPK scientists

Smartphone addiction fuels loneliness and reduces well-being, study finds

Mapping the brain: How cell types and location influence Parkinson’s disease

Better cognition and academic performance are associated with Mediterranean diet adherence

UMSOM wins $3.5 million BARDA contract to develop animals models for radiation research

Research unveils major discovery in gut-brain axis communication

Revolutionizing microscopy with affordable high-resolution techniques

Croatian sea fennel may contain a treasure trove of preservative and anti-aging metabolites

Boston College biologist wins NIH grant to study viral insulins for cancer treatment

New clinical practice guideline offers evidence-based recommendations for managing inhalant allergies with immunotherapy

Breakthrough research unveils β-cell dynamics in Type 1 diabetes

Study reveals BCG vaccine's unexpected role in fighting influenza

Gut bacteria may be responsible for sight loss in certain inherited eye diseases

Understanding obesity's effects on liver metabolism

Insights into gut plasticity mechanisms unveiled through fruit fly research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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