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Canagliflozin reduces atherosclerosis and modulates inflammatory, oxidative pathways in mice

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating the effect of canagliflozin (Cana) on atherosclerosis and further exploring its potential mechanism. ApoE−/− mice were fed a Western diet (WD) and randomly divided into a WD group and WD+Cana group.

19 Feb 2024

Study discovers link between a breakdown product from excess niacin and heart disease

Cleveland Clinic researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol.

19 Feb 2024

Dietary protein overload linked to increased atherosclerosis risk

University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk.

19 Feb 2024

A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries

Researchers conducted clinical studies on murine animals and humans to evaluate the impact of high protein intake on the amino acid-mammalian target of the rapamycin complex 1 autophagy signaling pathway.

19 Feb 2024

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Researchers utilized an untargeted metabolomics technique to look for new compounds and pathways that may contribute to residual cardiovascular disease risk.

19 Feb 2024

Husker research duo selected as Phase 1 winners in the NIH's Targeted Genome Editor Delivery Challenge

A Husker research duo was named a first-round winner in a National Institutes of Health competition aimed at generating solutions for delivering genome-editing technology to the cells of people with rare and common diseases.

19 Feb 2024

Survey of US adults reveals common cognitive symptoms in post-COVID-19 patients, linked to impaired daily functioning and depression

Scientists examined how prevalent self-reported cognitive symptoms were in individuals with post-COVID-19 condition as compared to individuals who had prior severe SARS-CoV-2 infections but had not developed post-COVID-19 condition.

19 Feb 2024

Associations between food additive emulsifiers and cancer risk

Researchers assessed associations between food emulsifier intake and cancer risk among NutriNet-Santé study participants.

19 Feb 2024

Can grandparental support improve the mental health of single mothers?

The role of grandparental support in protecting mothers from depression.

19 Feb 2024

Study provides evidence that antidepressant use in pregnancy affects child's brain development

A new study explored synapse maturation in the PFC of mice when exposed to 5-HT, shedding light on the link between the chemical and future behavioral changes.

19 Feb 2024

Identification of genetic determinants of micronucleus formation

The genetic determinants of micronuclei formation (MN).

19 Feb 2024

What factors are associated with recent prostate-specific antigen screening in transgender women?

A new study reports on factors associated with prostate cancer screening among transgender women.

19 Feb 2024

What is the association between relationship factors, financial difficulties, and socio-demographic factors with mental health?

The impact of marital/relationship perceptions, financial difficulties, and socio-demographic factors on mental health.

19 Feb 2024

Single-dose genetic medicine halts the progression of ALS and frontotemporal dementia in mice

Neuroscientists at Macquarie University in Australia have developed a single-dose genetic medicine that has been proven to halt the progression of both ALS and frontotemporal dementia (FTD) in mice – and may even offer the potential to reverse some of the effects of the fatal diseases.

19 Feb 2024

Medical Science News

Canagliflozin reduces atherosclerosis and modulates inflammatory, oxidative pathways in mice

Study discovers link between a breakdown product from excess niacin and heart disease

Dietary protein overload linked to increased atherosclerosis risk

A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Husker research duo selected as Phase 1 winners in the NIH's Targeted Genome Editor Delivery Challenge

Survey of US adults reveals common cognitive symptoms in post-COVID-19 patients, linked to impaired daily functioning and depression

Associations between food additive emulsifiers and cancer risk

Can grandparental support improve the mental health of single mothers?

Study provides evidence that antidepressant use in pregnancy affects child's brain development

Identification of genetic determinants of micronucleus formation

What factors are associated with recent prostate-specific antigen screening in transgender women?

What is the association between relationship factors, financial difficulties, and socio-demographic factors with mental health?

Single-dose genetic medicine halts the progression of ALS and frontotemporal dementia in mice

Discovery of novel enzyme family holds potential for antibiotic development

Exercise unleashes anti-inflammatory power against autoimmune diseases

From plate to planet: Innovative indicator tracks diet impact on health and environment

Reversing time: Hyaluronic acid injections offer lasting improvement in aging skin

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

Study reveals seasonal MERS-CoV peaks in Kenyan camels and potential human transmission

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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