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Researchers find new significant link between NPM protein and development of AML

A team of researchers from the National University of Singapore has found a new significant correlation between the protein nucleophosmin (NPM) and the development of an aggressive form of blood cancer called acute myeloid leukemia (AML).

8 Dec 2015

Simple approach to predict viral evolution may improve vaccine efficacy

New results from a study performed at the University of Helsinki suggest that genomic information from circulating influenza viruses can help in producing more efficient seasonal vaccines. The researchers were able to develop a simple approach for reliable real-time tracking and prediction of viral evolution based on whole-genome sequences of influenza viruses.

8 Dec 2015

Scientists reveal why loss of CD73 enzyme in human cancer promotes tumor progression

Scientists have shown for the first time why loss of the enzyme CD73 in human cancer promotes tumor progression.

8 Dec 2015

Existing compound offers hope for slowing Huntington's disease progression

Currently, there is no treatment to halt the progression of Huntington's disease (HD), a fatal genetic disorder that slowly robs sufferers of their physical and mental abilities. Now, researchers at University of California, San Diego School of Medicine have discovered that an existing compound, previously tested for diabetes, offers hope for slowing HD and its symptoms.

8 Dec 2015

Plasmacytoid dendritic cells may not contribute to late-stage lupus

For years, biomedical researchers have suspected that a specific set of immune cells are responsible for causing disease in lupus patients, but until now they haven't known for sure one way or the other.

8 Dec 2015

CTTV launches new web platform for identifying therapeutic targets

The Centre for Therapeutic Target Validation (CTTV) has launched a new web platform for life-science researchers that helps them identify therapeutic targets for new and repurposed medicines. Today's launch underscores the CTTV's commitment to share its data openly to benefit the broader scientific community.

8 Dec 2015

Macrophages play key role in maintaining healthy arteries after inflammation

Researchers from the University of Toronto have found that a specific cell type plays a key role in maintaining healthy arteries after inflammation. It's a discovery that could provide treatment options for cardiovascular disease -- one of the leading causes of death in Canada.

8 Dec 2015

NEK7 enzyme acts as on-off switch in innate immune system

UT Southwestern Medical Center and California researchers today provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system -- the body's first defense against infection.

8 Dec 2015

Stanford researchers invent new technique to dramatically accelerate protein evolution

All living things require proteins, members of a vast family of molecules that nature "makes to order" according to the blueprints in DNA.

8 Dec 2015

Researchers discover unique muscle fibers of upper airways often present in sleep apnea patients

Researchers at Umeå University in Sweden have discovered unique muscle fibers in the soft palate of the mouth in both infants and adults. The fibers seem to be present in greater number in snorers and sleep apnea patients.

8 Dec 2015

Study provides new insights into relationship between taste, behavior

Evolutionary conserved brainstem circuits are the first relay for gustatory information in the vertebrate brain. While the brainstem circuits act as our life support system and they mediate vital taste related behaviors, the principles of gustatory computations in these circuits are poorly understood.

8 Dec 2015

Researchers identify genes that act as brakes to stop development of aggressive type of leukaemia

Genes that act as brakes to stop the development of an aggressive form of leukaemia have been identified by researchers.

8 Dec 2015

Innovative DNA technology enables faster and more effective diagnosis of TB cases

Whole Genome Sequencing is a faster, cheaper and more effective way of diagnosing tuberculosis says a new study published in the journal Lancet Respiratory Medicine.

8 Dec 2015

TSRI scientists use new drug discovery technique to identify anti-diabetes compound

Scientists from The Scripps Research Institute have deployed a powerful new drug discovery technique to identify an anti-diabetes compound with a novel mechanism of action.

8 Dec 2015

Quest Diagnostics performs RNA testing on patient specimens to detect more cases of HCV

In its commitment to provide diagnostic insights that enhance patient care and outcomes, Quest Diagnostics will automatically perform molecular testing on all patient specimens whose antibody screening results indicate hepatitis C virus infection, and remove standalone positive antibody screening as a test option.

From Quest Diagnostics 8 Dec 2015

Gallstones, statins increase risk of acute pancreatitis, shows study

Idiopathic pancreatitis is often caused by small gallstones that are difficult to observe prior to surgery, shows a study from the University of Eastern Finland. Small gallstones were found in surgery from two out of three idiopathic pancreatitis patients.

8 Dec 2015

Faulty gene function responsible for reducing survival times of leukaemia patients

Researchers have identified a genetic fault in some leukaemia patients that could be responsible for halving survival times after diagnosis compared to patients without the fault – an average reduction from 16 years to seven years. T

8 Dec 2015

Study shows promise for cord blood-derived natural killer cells in multiple myeloma patients

A first-in-human Phase I study of multiple myeloma patients combined expanded cord blood-derived natural killer cells with transplantation of a patient's own stem cells and high-dose chemotherapy with little or none of the side effects seen with current treatments.

8 Dec 2015

Researchers reveal potential for exploring new treatment options for triple-negative breast cancer

Researchers from Caris Life Sciences and Fox Chase Cancer Center – Temple Health announced the presentation of two studies revealing the potential for exploring new therapeutic options for triple-negative breast cancer (TNBC) at the 2015 San Antonio Breast Cancer Symposium.

7 Dec 2015

Scientists decipher details of cloaking proteins that protect the toxin that causes botulism

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and collaborators at Stony Brook University and the Institute of Advanced Sciences in Dartmouth, Massachusetts, have discovered new details about how "cloaking" proteins protect the toxin that causes botulism, a fatal disease caused most commonly by consuming improperly canned foods.

7 Dec 2015

Medical Science News

Researchers find new significant link between NPM protein and development of AML

Simple approach to predict viral evolution may improve vaccine efficacy

Scientists reveal why loss of CD73 enzyme in human cancer promotes tumor progression

Existing compound offers hope for slowing Huntington's disease progression

Plasmacytoid dendritic cells may not contribute to late-stage lupus

CTTV launches new web platform for identifying therapeutic targets

Macrophages play key role in maintaining healthy arteries after inflammation

NEK7 enzyme acts as on-off switch in innate immune system

Stanford researchers invent new technique to dramatically accelerate protein evolution

Researchers discover unique muscle fibers of upper airways often present in sleep apnea patients

Study provides new insights into relationship between taste, behavior

Researchers identify genes that act as brakes to stop development of aggressive type of leukaemia

Innovative DNA technology enables faster and more effective diagnosis of TB cases

TSRI scientists use new drug discovery technique to identify anti-diabetes compound

Quest Diagnostics performs RNA testing on patient specimens to detect more cases of HCV

Gallstones, statins increase risk of acute pancreatitis, shows study

Faulty gene function responsible for reducing survival times of leukaemia patients

Study shows promise for cord blood-derived natural killer cells in multiple myeloma patients

Researchers reveal potential for exploring new treatment options for triple-negative breast cancer

Scientists decipher details of cloaking proteins that protect the toxin that causes botulism

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