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Researchers find mechanism to repair communication between neurons

A team of researchers led by professor Patrik Verstreken (VIB/KU Leuven) has exposed the fine details of a mechanism that provides more insight in the communication between neurons. The research has clarified how damaged synapses - the connection points between neurons - are repaired to keep communication between neurons at an optimal level.

19 Nov 2015

ProMetic, ProThera form strategic partnership to develop and commercialize Inter-alpha Inhibitor Proteins

ProMetic Life Sciences Inc. announced today that it has entered into a strategic partnership with ProThera Biologics Inc. for the development and commercialization of human plasma-derived Inter-alpha Inhibitor Proteins.

19 Nov 2015

Identifying new mechanism for aspirin in cancer prevention

Aspirin has been shown to decrease the risk of colorectal cancer and possibly other cancers. However, the risk of side effects, including in some cases severe gastrointestinal bleeding, makes it necessary to better understand the mechanisms by which aspirin acts at low doses before recommending it more generally as a preventative, says Cornelia Ulrich, PhD, Senior Director of Population Sciences at Huntsman Cancer Institute in Salt Lake City.

19 Nov 2015

Sildenafil drug improves insulin sensitivity in people at risk for diabetes

The drug sildenafil, sold as Viagra and other brand names, improves insulin sensitivity in people at risk for diabetes, researchers at Vanderbilt University Medical Center reported today.

19 Nov 2015

University of York researchers unveil 3-D structure of cancer target enzyme

A team from the University of York has published research unveiling the 3-D structure of human heparanase, a sugar-degrading enzyme which has received significant attention as a key target in anti-cancer treatments.

19 Nov 2015

Role of genetic predisposition in pediatric cancer patients

The most detailed analysis yet of the role germline mutations in genes associated with cancer predisposition play in the development of childhood cancer suggests that comprehensive genomic screening may be warranted on all pediatric cancer patients, not just those with a family history of cancer.

19 Nov 2015

Testosterone cause of sex differences in the occurrence of Parkinson’s disease, new research suggests

Men are twice as likely as women to develop Parkinson's disease, a nervous system disorder characterized by tremors and difficulty moving. New research to be presented at Cardiovascular, Renal and Metabolic Diseases: Physiology and Gender suggests that the difference in risk may be due to the presence of the male sex hormone testosterone.

19 Nov 2015

New technique improves accuracy of CRISPR/Cas9 gene editing system

A new CRISPR/Cas9 technology developed by scientists at the University of Massachusetts Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.

19 Nov 2015

Role of biomarkers in drug development and regulatory decision making

Biomarkers in Medicine, a leading MEDLINE-indexed journal, has published a special focus issue exploring the increasingly important role of biomarkers in both drug development and regulatory decision making.

19 Nov 2015

Scientists, chefs explore ways to help people with neurologically-related taste impairments enjoy food again

Two women, seated at a table, told their stories in quiet tones. A group of chefs, some standing, others seated, leaned forward eagerly, clearly interested in what these two women had to say. They peppered the women with questions: did food taste better cold or hot? Was texture an issue? Did a glass of wine before dinner help or hurt the flavor experience? The women have taken chemotherapy for their cancer. One of them -- Gina Mullin -- will be taking chemotherapy every three weeks for the rest of her life. Both of them tell heartbreaking stories about a side effect of chemotherapy that gets swept under the rug: food tastes terrible.

19 Nov 2015

Sound deprivation causes irreversible damage to the inner ear

Massachusetts Eye and Ear investigators have shown that sound deprivation in adult mice causes irreversible damage to the inner ear. The findings, published in PLOS ONE, suggest that chronic conductive hearing loss, such as that caused by recurrent ear infections, leads to permanent hearing impairment if it remains untreated.

19 Nov 2015

Dartmouth study reveals the brain's visual pathways

A Dartmouth study reveals how the brain understands motion and still objects to help us navigate our complex visual world.

19 Nov 2015

IMB scientists unravel complex regulatory mechanism involved in brain development

Scientists at the Institute of Molecular Biology in Mainz have unraveled a complex regulatory mechanism that explains how a single gene can drive the formation of brain cells. The research, published in The EMBO Journal, is an important step towards a better understanding of how the brain develops. It also harbors potential for regenerative medicine.

19 Nov 2015

Houston Methodist invention named one of 100 most innovative technologies by R&D Magazine

R&D Magazine named the handheld single-cell pipette (hSCP), a Houston Methodist Research Institute invention, as one the 100 most innovative technologies and services of the past year.

19 Nov 2015

International task force aims to develop new approach to cancer prevention and treatment

Advancements in precision medicine have led to many new targeted cancer therapies for cancer patients. These treatments focus on using agents that target one or two genes that contribute to tumor development. The approach tends to be more effective against cancer cells and less toxic toward normal cells than standard chemotherapeutic regimens.

19 Nov 2015

ICGC announces availability of more genomic data on Amazon Web Services Cloud for cancer researchers

The International Cancer Genome Consortium announced today that 1,200 encrypted cancer whole genome sequences are now securely available on the Amazon Web Services (AWS) Cloud for access by cancer researchers worldwide.

19 Nov 2015

Potential treatment strategy for glycogen storage disease

Researchers from the Duke-NUS Graduate Medical School Singapore and Duke Medicine have identified a potential treatment strategy for an often-fatal inherited glycogen storage disease.

18 Nov 2015

Cell Therapy Catapult initiates construction for cell and gene therapy manufacturing centre

The Cell Therapy Catapult, the UK organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the official initiation of construction for its cell and gene therapy manufacturing centre.

18 Nov 2015

Duchenne muscular dystrophy could directly affect muscle stem cells

A new study from The Ottawa Hospital and the University of Ottawa is poised to completely change our understanding of Duchenne muscular dystrophy and pave the way for far more effective treatments.

18 Nov 2015

Serum phosphorus levels can help predict risk of ESRD in African Americans with CKD

An increase in serum phosphorus levels in African Americans with chronic kidney disease (CKD) is associated with faster progression to kidney failure, known as end-stage renal disease (ESRD), according to new research presented at ASN Kidney Week 2015 November 3-8 in San Diego, CA. Previously confirmed in primarily Caucasian populations, the Indiana University School of Medicine study confirms serum phosphorus is linked to ESRD risk in African Americans.

18 Nov 2015

Medical Science News

Researchers find mechanism to repair communication between neurons

ProMetic, ProThera form strategic partnership to develop and commercialize Inter-alpha Inhibitor Proteins

Identifying new mechanism for aspirin in cancer prevention

Sildenafil drug improves insulin sensitivity in people at risk for diabetes

University of York researchers unveil 3-D structure of cancer target enzyme

Role of genetic predisposition in pediatric cancer patients

Testosterone cause of sex differences in the occurrence of Parkinson’s disease, new research suggests

New technique improves accuracy of CRISPR/Cas9 gene editing system

Role of biomarkers in drug development and regulatory decision making

Scientists, chefs explore ways to help people with neurologically-related taste impairments enjoy food again

Sound deprivation causes irreversible damage to the inner ear

Dartmouth study reveals the brain's visual pathways

IMB scientists unravel complex regulatory mechanism involved in brain development

Houston Methodist invention named one of 100 most innovative technologies by R&D Magazine

International task force aims to develop new approach to cancer prevention and treatment

ICGC announces availability of more genomic data on Amazon Web Services Cloud for cancer researchers

Potential treatment strategy for glycogen storage disease

Cell Therapy Catapult initiates construction for cell and gene therapy manufacturing centre

Duchenne muscular dystrophy could directly affect muscle stem cells

Serum phosphorus levels can help predict risk of ESRD in African Americans with CKD

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