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Phase 1 trial to examine efficacy of promising malaria vaccine in Burkina Faso

Malaria is one of the world's deadliest diseases: it infects hundreds of millions of people every year, and kills about half a million, most of them under five years of age.

6 Jul 2016

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Precise predictions of whether a tumor is likely to spread would help clinicians and patients choose the best course of treatment. But current methods fall short of the precision needed.

6 Jul 2016

Conceptual model highlights transmission of chronic pain risk from parent to children

Can an increased risk of chronic pain be transmitted from parents to children? Several factors may contribute, including genetics, effects on early development, social learning, and more according to a report in the journal PAIN, the official publication of the International Association for the Study of Pain.

6 Jul 2016

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Maple Syrup Urine Disease (MSUD) is a rare inherited metabolic disorder involving the dysfunction of an enzyme which breaks down three essential amino acids: leucine, isoleucine and valine.

6 Jul 2016

Scientists use Sure Chill technology to develop cost-effective vaccine storage

Vaccines against killer diseases from polio to hepatitis are fragile and can easily be made useless if they get too hot or too cold.

6 Jul 2016

Researchers use FRET to make activation of AMPA receptors optically visible

Our brain is a high-performance computer. One of the key players in this complex system is the AMPA-type glutamate receptor. It ensures that neurotransmission proceeds at a breakneck pace from cell to cell.

6 Jul 2016

Study finds no substantial link between gadolinium exposure and parkinsonism

In a study appearing in the July 5 issue of JAMA, Blayne Welk, M.D., M.Sc., of Western University, London, Canada, and colleagues conducted a study to assess the association between gadolinium exposure and parkinsonism, a degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination.

6 Jul 2016

PREVAIL IV trial opens in Liberia for EVD survivors with persistent traces of Ebola virus RNA

The Partnership for Research on Ebola Virus in Liberia, a U.S.-Liberia joint Clinical Research Partnership, today announced the opening of PREVAIL IV, a treatment trial for men who have survived Ebola virus disease (EVD) but continue to have evidence of Ebola virus genetic material, RNA, in their semen.

6 Jul 2016

Sleep disturbances, long sleep duration linked to inflammatory illnesses

A new meta-analysis in Biological Psychiatry reports that sleep disturbances and long sleep duration are associated with increases in markers of inflammation.

6 Jul 2016

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

Researchers from the University of Zurich and University Children's Hospital Zurich have discovered the first X-chromosome-inherited type of the congenital disease osteogenesis imperfecta, also known as brittle-bone disease.

6 Jul 2016

New lung-targeted gene therapy shows promise in improving treatment for emphysema

Researchers have developed a new strategy using lung-targeted gene therapy that may lead to improved treatments for inherited diseases including emphysema.

6 Jul 2016

Researchers find distinct, non-identical differences among retroviruses

In the most comprehensive study of its kind, researchers in the report that most types of retroviruses have distinct, non-identical virus structures.

6 Jul 2016

Rapid number naming test can detect cognitively impaired people with AD

For the first time, researchers have determined that a brief, simple number naming test can differentiate between cognitively healthy elderly individuals and cognitively impaired people with Alzheimer's disease (AD), including those with mild cognitive impairment (MCI), as well as those with AD dementia.

6 Jul 2016

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

Researchers at University of California San Diego School of Medicine say tiny micro-vesicle structures used by neurons and other cells to transport materials internally or dispose of them externally carry tell-tale proteins that may help to predict the likelihood of mild cognitive impairment (MCI) developing into full-blown Alzheimer's disease (AD).

6 Jul 2016

Religious attendance can help decrease pornography viewing in adolescents

A new study authored by University of Calgary researchers in the Journal of Adolescence examines the pornography viewing habits of adolescents and observes the way in which religious attendance significantly tempers such actions.

6 Jul 2016

Researchers identify potential biomarker for Parkinson's disease in biobanked urine samples

For more than five years, urine and cerebral-spinal fluid samples from patients with Parkinson's disease have been locked in freezers in the NINDS National Repository, stored with the expectation they might someday help unravel the still-hidden course of this slow-acting neurodegenerative disease.

6 Jul 2016

Researchers identify astroglia-mediated mechanism for causing FXS symptoms in mice

A study published today in the Journal of Neuroscience led by Yongjie Yang of Tufts University School of Medicine identifies an astroglial trigger mechanism as contributing to symptoms of fragile X syndrome in mice.

6 Jul 2016

Mice study shows how multiple malaria infections lead to increased health risks

Scientists have discovered why infections with two types of malaria parasite lead to greater health risks - because one species helps the other to thrive.

6 Jul 2016

Changes in neural circuit involved in emotional resilience may help youngsters adapt to childhood adversity

A new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging reports a neural signature of emotional adaptation that could help researchers understand how the brain adapts to childhood adversity and predict which kids may be vulnerable to developing later psychopathology.

6 Jul 2016

Researchers demonstrate simple approach to prove how classes of new drugs work

A collaborative effort by cancer researchers at Cold Spring Harbor Laboratory and chemists at Boehringer Ingelheim, a pharmaceutical firm, has resulted in the identification of a new drug target in leukemia and creation of a candidate drug that hits the target.

6 Jul 2016

Medical Science News

Phase 1 trial to examine efficacy of promising malaria vaccine in Burkina Faso

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Conceptual model highlights transmission of chronic pain risk from parent to children

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Scientists use Sure Chill technology to develop cost-effective vaccine storage

Researchers use FRET to make activation of AMPA receptors optically visible

Study finds no substantial link between gadolinium exposure and parkinsonism

PREVAIL IV trial opens in Liberia for EVD survivors with persistent traces of Ebola virus RNA

Sleep disturbances, long sleep duration linked to inflammatory illnesses

Scientists discover X-chromosome-inherited type of osteogenesis imperfecta

New lung-targeted gene therapy shows promise in improving treatment for emphysema

Researchers find distinct, non-identical differences among retroviruses

Rapid number naming test can detect cognitively impaired people with AD

Tiny micro-vesicle structures may help predict probability of developing Alzheimer's dementia

Religious attendance can help decrease pornography viewing in adolescents

Researchers identify potential biomarker for Parkinson's disease in biobanked urine samples

Researchers identify astroglia-mediated mechanism for causing FXS symptoms in mice

Mice study shows how multiple malaria infections lead to increased health risks

Changes in neural circuit involved in emotional resilience may help youngsters adapt to childhood adversity

Researchers demonstrate simple approach to prove how classes of new drugs work

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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