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Neuroscientists reveal the brain malady responsible for tinnitus, chronic pain

Neuroscientists at Georgetown University Medical Center and Germany's Technische Universität München say they've uncovered the brain malady responsible for tinnitus and for chronic pain — the uncomfortable, sometimes agonizing sensations that persist long after an initial injury.

24 Sep 2015

Research suggests potential drug targets to stop cancer spread

It only takes seconds: one cancerous cell breaks off from a tumor, slips into the bloodstream and quickly lodges elsewhere in the body. These colonizers may bloom into deadly metastatic cancer right away or lie dormant for years, only to trigger a recurrence decades after the primary tumor is removed.

24 Sep 2015

Stanford researchers successfully defeat C. difficile bacteria

Stanford University School of Medicine scientists successfully defeated a dangerous intestinal pathogen, Clostridium difficile, with a drug targeting its toxins rather than its life.

24 Sep 2015

Novel approach promises easier way to detect protein fibers implicated in neuro-degenerative diseases

Liquid crystals are familiar to most of us as the somewhat humdrum stuff used to make computer displays and TVs. Even for scientists, it has not been easy to find other ways of using them.

24 Sep 2015

TUM, Stanford University scientists create new cancer therapy concept

Pancreatic cancer is one of the most aggressive forms of cancer and one of the most difficult to treat. Its high resistance to treatment is a major problem, particularly in the advanced stages.

24 Sep 2015

Scientists trace out intricate molecular pathway that may explain tamoxifen resistance in breast cancer patients

For reasons unknown, many patients with breast cancer treated with the estrogen receptor-blocking drug tamoxifen eventually become resistant to the treatment despite the fact that their cancer cells still have the estrogen receptor proteins that the drug normally targets.

24 Sep 2015

Study uses genome- and epigenome-editing tools to determine disease-causing variants

A paper receiving advance online release in Nature Medicine describes a strategy for meeting one of today's most significant challenges in genomic medicine - determining whether a specific DNA variant in the non-protein-coding genome is the actual disease-causing variant of an associated disease risk.

24 Sep 2015

Researchers develop promising metal-based compound to fight kidney cancer

Researchers developed a promising metal-based compound that destroys kidney cancer cells, while leaving normal cells unharmed. The findings may provide a new way of treating kidney cancer, opening the potential for more potent and less toxic therapies that would give cancer patients a better quality of life.

24 Sep 2015

Soft palate plays key role in viruses' ability to spread

Flu viruses come in many strains, and some are better equipped than others to spread from person to person. Scientists have now discovered that the soft palate -- the soft tissue at the back of the roof of the mouth -- plays a key role in viruses' ability to travel through the air from one person to another.

24 Sep 2015

UT Southwestern researchers find a previously unknown genetic code

UT Southwestern physiologists trying to understand the genetic code have found a previously unknown code that helps explain which protein should be created to form a particular type of cell.

24 Sep 2015

NGN3-expressing cells in adult human pancreas offer hope to diabetics

Cells that express neurogenin 3 (NGN3) may one day be harnessed to create a plentiful supply of insulin-producing beta cells for the treatment of diabetes, a study led by researchers at the University of South Florida suggests.

24 Sep 2015

MIT neuroscientists identify brain circuit critical in forming episodic memory

When you remember a particular experience, that memory has three critical elements -- what, when, and where. MIT neuroscientists have now identified a brain circuit that processes the "when" and "where" components of memory.

24 Sep 2015

MIT researchers devise new system to genetically engineer viruses to combat harmful bacteria

In the hunt for new ways to kill harmful bacteria, scientists have turned to a natural predator: viruses that infect bacteria. By tweaking the genomes of these viruses, known as bacteriophages, researchers hope to customize them to target any type of pathogenic bacteria.

23 Sep 2015

ASU and three partner institutions awarded NSF grant to study how healthy brains create memories of odors

Like most animals, we rely on our sense of smell for survival. It's critical to our health and an important factor in our quality of life.

23 Sep 2015

Matricellular proteins may be key therapeutic targets for common ocular disorders

A special issue of Journal of Ocular Pharmacology and Therapeutics highlights the latest research on matricellular proteins, which play a critical role in inflammation and blood vessel formation in the eye and therefore making them key targets for new therapies to treat common ocular disorders such as glaucoma, dry eye disease, and age-related macular degeneration (AMD).

23 Sep 2015

New analysis shows rare gene mutations cause half of all ASD cases

A team led by researchers at Cold Spring Harbor Laboratory (CSHL) this week publishes in PNAS a new analysis of data on the genetics of autism spectrum disorder (ASD).

23 Sep 2015

S. Lawrence Zipursky to receive 2015 Louisa Gross Horwitz Prize from Columbia University

Columbia University will award the 2015 Louisa Gross Horwitz Prize to S. Lawrence Zipursky, PhD, for discovering a molecular identification system that helps neurons to navigate and wire the brain. Zipursky is a professor of biological chemistry at the University of California, Los Angeles and a Howard Hughes Medical Institute investigator.

23 Sep 2015

Researchers receive NIH grants to find genomic regions containing variants that affect disease risk

Six new grants from the National Institutes of Health will support researchers to develop new computational approaches for searching among millions of genomic variants to find those that make a difference in disease susceptibility or in other traits.

23 Sep 2015

TSRI scientists awarded grant from Gates Foundation to develop revolutionary alternative HIV/AIDS vaccine

Scientists from the Florida campus of The Scripps Research Institute have been awarded up to nearly $6 million dollars from the Bill & Melinda Gates Foundation to develop a revolutionary HIV/AIDS alternative vaccine that has demonstrated great potential in animal models.

23 Sep 2015

Radboud university medical center reveals how BCG vaccine works against tuberculosis

Not only the acquired immune system but also the innate immune system has a memory. And the BCG vaccine against tuberculosis can stimulate this memory. After a BCG vaccination the innate immune system responds better to a wide range of other infections. Mihai Netea and colleagues from Radboud university medical center discovered and described how that works. They think that the old vaccine could be useful for specific target groups, such as the elderly.

23 Sep 2015

Medical Science News

Neuroscientists reveal the brain malady responsible for tinnitus, chronic pain

Research suggests potential drug targets to stop cancer spread

Stanford researchers successfully defeat C. difficile bacteria

Novel approach promises easier way to detect protein fibers implicated in neuro-degenerative diseases

TUM, Stanford University scientists create new cancer therapy concept

Scientists trace out intricate molecular pathway that may explain tamoxifen resistance in breast cancer patients

Study uses genome- and epigenome-editing tools to determine disease-causing variants

Researchers develop promising metal-based compound to fight kidney cancer

Soft palate plays key role in viruses' ability to spread

UT Southwestern researchers find a previously unknown genetic code

NGN3-expressing cells in adult human pancreas offer hope to diabetics

MIT neuroscientists identify brain circuit critical in forming episodic memory

MIT researchers devise new system to genetically engineer viruses to combat harmful bacteria

ASU and three partner institutions awarded NSF grant to study how healthy brains create memories of odors

Matricellular proteins may be key therapeutic targets for common ocular disorders

New analysis shows rare gene mutations cause half of all ASD cases

S. Lawrence Zipursky to receive 2015 Louisa Gross Horwitz Prize from Columbia University

Researchers receive NIH grants to find genomic regions containing variants that affect disease risk

TSRI scientists awarded grant from Gates Foundation to develop revolutionary alternative HIV/AIDS vaccine

Radboud university medical center reveals how BCG vaccine works against tuberculosis

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