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Study reveals how leukemia cells evade deadly effects of BRD4 inhibitors

BRD4 inhibitors are among the most promising new agents in cancer therapy that are currently evaluated in clinical trials.

15 Sep 2015

$Whole-genome sequencing identifies EN1 gene as determinant of bone mineral density, fracture$

Whole-genome sequencing identifies EN1 gene as determinant of bone mineral density, fracture

Using extensive genetic data compiled by the UK10K project, an international team of researchers led by Dr. Brent Richards of the Lady Davis Institute at the Jewish General Hospital has identified a genetic variant near the gene EN1 as having the strongest effect on bone mineral density (BMD) and fracture identified to date.

15 Sep 2015

Molecular biology research holds promise in understanding cancer growth, aging

Researchers at the Johns Hopkins University have found molecular evidence of how a biochemical process controls the lengths of protective chromosome tips, a potentially significant step in ultimately understanding cancer growth and aging.

15 Sep 2015

BfArM approves Greenovation’s moss-aGal phase I clinical trial for Fabry disease

Greenovation Biotech GmbH announced today that it has received approval to begin a phase I clinical trial in Europe for its first drug candidate moss-aGal (agalsidase) from Germany's regulatory authority, the Federal Institute for Drugs and Medical Devices (BfArM).

15 Sep 2015

New strategy improves bone repair by boosting survival rate of transplanted stem cells

Stem cell therapies are often limited by low survival of transplanted stem cells and the lack of precise control over their differentiation into the terminal cell types needed to repair or replace injured tissues. Now, a team led by Wyss Institute Core Faculty member David Mooney, Ph.D., has developed a new strategy - embedding stem cells into porous, transplantable hydrogels - that has experimentally improved bone repair by boosting the survival rate of transplanted stem cells and influencing their cell differentiation.

15 Sep 2015

Researchers show how a cell surface protein can mobilize immune cells to attack malignant tumors

Revealing a biological combat strategy worthy of a five-star general, researchers from Houston Methodist Hospital, University of Chicago and Cornell University have shown how a cell surface receptor--a specialized protein which communicates signals between a cell and the outside world--can mobilize immune cells to attack, rather than protect, malignant tumors.

15 Sep 2015

Inhibition of FGFR3 receptor could be a new way of treating patients with liver cell cancer

In a recent study, scientists from the Institute for Cancer Research at MedUni Vienna have shown that the growth factor receptor FGFR3 increases the rate of growth and aggressiveness of hepatocellular carcinomas (liver cell cancer). Inhibition of this receptor could be a new and effective way of treating patients.

15 Sep 2015

Combining epigenetic drugs with immunotherapies may provide additional clinical benefit to cancer patients

Recent data suggest that epigenetic therapies are likely to provide additional clinical benefit to cancer patients when rationally combined with immunotherapeutic drugs, according to a review published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

15 Sep 2015

Missing part of the brain may play vital role in how people understand the world

A study three years ago sparked a medical mystery when it revealed a part of the brain not found in any present-day anatomy textbooks.

15 Sep 2015

Scientists identify a gene that can cause more aggressive cancer in AML patients

University of Manchester scientists have identified a gene - FOXC1 - that, if switched on, causes more aggressive cancer in a fifth of acute myeloid leukaemia (AML) patients, according to a Cancer Research UK study published in the journal Cancer Cell, today (Monday).

14 Sep 2015

Human Brain Project aims at detailed simulations of human brain

The goal of brain simulations using supercomputers is to understand the processes in our brain. This is a mammoth task: the activity of an estimated 100 billion nerve cells - also known as neurons - must be represented .

14 Sep 2015

Researchers examine neuroanatomical signature of schizophrenia in different ethnic groups

While it is known that the incidence and outward symptoms of schizophrenia are strongly influenced by ethnic factors--for instance, patients from Asian ethnicities are more likely to experience visual hallucinations, whereas patients from western cultures and Caucasian ethnicities are more likely to suffer from auditory hallucinations--it was unclear if brain deficits would differ amongst suffers from various ethnic backgrounds.

14 Sep 2015

Innovative mouse study could lead to advances in understanding autism

They don't use gondolas or croon like Sinatra. But scientists have known for a long time that male mice belt out something like love songs to females when the time seems right to them.

14 Sep 2015

Location-dependent pattern in cilia length in mouse nasal cavity affects sensitivity to odors

Like the hairs they resemble, cilia come in all lengths, from short to long. But unlike the hair on our heads, the length of sensory cilia on nerve cells in our noses is of far more than merely cosmetic significance. A team of researchers from the Perelman School of Medicine at the University of Pennsylvania found a location-dependent pattern in cilia length in the mouse nasal cavity that affects sensitivity to odors.

14 Sep 2015

Umeå University chemist explores ways to decrease bacterial colonization

Among the bacterial infections that are most difficult to treat, chronic infections associated with bacterial biofilms are one of the most hazardous. Bacterial biofilms are densely packed communities of microbial cells surrounded with secreted polymers. In her doctoral thesis, chemist Shoghik Hakbyan has studied ways to decrease the bacterial colonization at Umeå University in Sweden.

14 Sep 2015

Earliest known case of rickets in the UK identified in Neolithic Tiree skeleton

Rickets has been identified in a Neolithic skeleton from the Scottish island of Tiree, making it the earliest case of the disease in the UK, according to research announced at the British Science Festival in Bradford.

14 Sep 2015

Virginia Tech scientists discover new treatments to target antibiotic-resistant bacteria

Virginia Tech researchers have discovered a new group of antibiotics that may provide relief to some of the more than 2 million people in the United States affected by antibiotic resistance.

14 Sep 2015

Mordor Intelligence announces publication of global whey protein market report

Mordor Intelligence is pleased to announce the publication of the report on Global Whey Protein Market on September 14, 2015. This report discusses the market in detail.

14 Sep 2015

Study finds association between long sleep duration and high serum copper concentration

Persons sleeping less than 6 hours or more than 10 hours suffer from low-grade inflammation more often than persons sleeping 7-8 hours per night. This was observed in a University of Eastern Finland study focusing on the health and lifestyle habits among middle-aged men.

14 Sep 2015

Genetics and race influence patients' response to anticancer drug treatments

A new study published in Pharmacogenomics suggests that a person's response to anticancer drug treatments is strongly related to their genetic ancestry. Pharmacogenomics is published by Future Science Group.

14 Sep 2015

Medical Science News

Study reveals how leukemia cells evade deadly effects of BRD4 inhibitors

Whole-genome sequencing identifies EN1 gene as determinant of bone mineral density, fracture

Molecular biology research holds promise in understanding cancer growth, aging

BfArM approves Greenovation’s moss-aGal phase I clinical trial for Fabry disease

New strategy improves bone repair by boosting survival rate of transplanted stem cells

Researchers show how a cell surface protein can mobilize immune cells to attack malignant tumors

Inhibition of FGFR3 receptor could be a new way of treating patients with liver cell cancer

Combining epigenetic drugs with immunotherapies may provide additional clinical benefit to cancer patients

Missing part of the brain may play vital role in how people understand the world

Scientists identify a gene that can cause more aggressive cancer in AML patients

Human Brain Project aims at detailed simulations of human brain

Researchers examine neuroanatomical signature of schizophrenia in different ethnic groups

Innovative mouse study could lead to advances in understanding autism

Location-dependent pattern in cilia length in mouse nasal cavity affects sensitivity to odors

Umeå University chemist explores ways to decrease bacterial colonization

Earliest known case of rickets in the UK identified in Neolithic Tiree skeleton

Virginia Tech scientists discover new treatments to target antibiotic-resistant bacteria

Mordor Intelligence announces publication of global whey protein market report

Study finds association between long sleep duration and high serum copper concentration

Genetics and race influence patients' response to anticancer drug treatments

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