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Study provides more insight into treatment options for severe hemophilia A

Families of children with severe hemophilia A may want to take a fresh look at treatment options from human plasma. A study published in the New England Journal of Medicine on May 26 showed that participants who received a recombinant therapy— the present standard in the United States — developed antibodies or "inhibitors" to the treatments at almost twice the rate as those whose treatments were made from human plasma.

14 Jun 2016

EPFL researchers reprogram TAMs to prevent tumor metastasis

One of the major obstacles with treating cancer is that tumors can conscript the body's immune cells and make them work for them. Researchers at EPFL have now found a way to reclaim the corrupted immune cells, turn them into signals for the immune system to attack the tumor, and even prevent metastasis.

14 Jun 2016

Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding that joins molecules together could be the key to our battle against antibiotic resistance. Research published in Bioorganic & Medicinal Chemistry Letters shows that carbon nanodot scaffolding assembled with small molecules called polyamines can kill some dangerous drug-resistant bacteria, including Acinetobacter baumanii and Klebsiella pneumonia.

14 Jun 2016

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Cisplatin is a common, powerful chemotherapy agent used for a wide range of cancers such as breast, ovarian and lung, that in a handful of days can also permanently damage or destroy patients' kidneys.

14 Jun 2016

Gist reasoning training can strengthen cognitive domains in individuals with MCI

New research from the Center for BrainHealth at The University of Texas at Dallas shows that strategy-based reasoning training can improve the cognitive performance for those with mild cognitive impairment (MCI), a preclinical stage of those at risk for Alzheimer's disease.

14 Jun 2016

Prkci gene plays role in organizing cells during early embryo, organ formation

A gene called Prkci can point cells in the right direction, according to a new study in Developmental Biology.

14 Jun 2016

Pediatric diseases and treatment could have greater impact on intestinal microbial diversity

Tracy C. Grikscheit, MD, pediatric surgeon and principal investigator at The Saban Research Institute of Children's Hospital Los Angeles, treats a large number of young patients who require surgery for various intestinal diseases.

14 Jun 2016

New receptor discovery could lead to novel mosquito repellents

Major rainfall across most of Texas triggering hordes of mosquitos coupled with seemingly constant mosquito-related Zika virus media reports from around the globe may have set the stage perfectly for what one researcher deems as a very significant discovery in man's war against earth's leading human disease carrier.

14 Jun 2016

Adequate maternal folate may protect children from future obesity risk

Proper maternal folate levels during pregnancy may protect children from a future risk of obesity, especially those born to obese mothers, according to a study led by researchers funded by the National Institutes of Health.

14 Jun 2016

New nano-fabricated platform provides accurate post-surgery prognosis for glioblastoma patients

A new nano-fabricated platform for observing brain cancer cells provides a much more detailed look at how the cells migrate and a more accurate post-surgery prognosis for brain cancer (glioblastoma) patients.

14 Jun 2016

T memory cells with naive phenotype can help boost immunity in older adults

Sixty-five is the age when many people retire, kick back and take it easy. And so it often is with the human immune system.

14 Jun 2016

OIST researchers discover unique copper-silver nanoparticle structure

Sometimes it is the tiny things in the world that can make an incredible difference. One of these things is the nanoparticle. Nanoparticles may be small, but they have a variety of important applications in areas such as, medicine, manufacturing, and energy.

14 Jun 2016

Researchers unravel species-function relationships in gut microbial genomes

Despite recent progress, the organization and ecological properties of the intestinal microbial ecosystem remain under investigated. Using a manually curated metabolic module framework for (meta-)genomic data analysis, Sara Vieira-Silva, Gwen Falony and colleagues from the Jeroen Raes lab studied species-function relationships in gut microbial genomes and microbiomes.

14 Jun 2016

U-M researchers explore new way to improve cognitive issues in MS patients

Multiple sclerosis looks different from person to person. In many individuals, though, the difficulty in maintaining a sense of self and in keeping up intellectually can be the disease's most devastating manifestations.

14 Jun 2016

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

Alzheimer's is a devastating and incurable disease marked by beta-amyloid and tau protein aggregations in the brain, yet the direct relationship between these proteins and neurodegeneration has remained a mystery.

14 Jun 2016

Scientists find new way to slow growth of triple negative breast cancer

CANCER RESEARCH UK scientists have found a new way to slow the growth of the most aggressive type of breast cancer, according to research published in the journal Oncogene today (Monday).

14 Jun 2016

Study underscores importance of developing PRMT5 inhibitors as promising treatment for GB patients

A new study suggests that blocking an enzyme called PRMT5 in tumor cells could be a promising new strategy for the treatment of glioblastoma (GB), the most aggressive and lethal form of brain cancer.

14 Jun 2016

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

A study in the Journal of the American Society of Nephrology suggests a new therapeutic approach to treat the development of chronic kidney disease secondary to chronic heart failure, known as cardiorenal syndrome type 2.

14 Jun 2016

Study opens up new strategy to make immunotherapy more effective for different cancer types

By combining local radiation therapy and anti-cancer vaccines with checkpoint inhibitors, researchers from the University of Chicago, working with mice, were able to increase the response rate for these new immunotherapy agents.

14 Jun 2016

PET imaging can help identify autoimmune inflammation in MS

The triggers of autoimmune inflammation in multiple sclerosis (MS) have eluded scientists for many years, but molecular imaging is bringing researchers closer to identifying them, while providing a means of evaluating next-generation therapies for MS, say researchers introducing a study at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging.

14 Jun 2016

Medical Science News

Study provides more insight into treatment options for severe hemophilia A

EPFL researchers reprogram TAMs to prevent tumor metastasis

Tiny molecular scaffolding could be key to fight against antibiotic resistance

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Gist reasoning training can strengthen cognitive domains in individuals with MCI

Prkci gene plays role in organizing cells during early embryo, organ formation

Pediatric diseases and treatment could have greater impact on intestinal microbial diversity

New receptor discovery could lead to novel mosquito repellents

Adequate maternal folate may protect children from future obesity risk

New nano-fabricated platform provides accurate post-surgery prognosis for glioblastoma patients

T memory cells with naive phenotype can help boost immunity in older adults

OIST researchers discover unique copper-silver nanoparticle structure

Researchers unravel species-function relationships in gut microbial genomes

U-M researchers explore new way to improve cognitive issues in MS patients

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

Scientists find new way to slow growth of triple negative breast cancer

Study underscores importance of developing PRMT5 inhibitors as promising treatment for GB patients

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

Study opens up new strategy to make immunotherapy more effective for different cancer types

PET imaging can help identify autoimmune inflammation in MS

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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