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Researchers identify potential ways in which cancer cells may develop resistance to BET inhibitors

A team of Walter and Eliza Hall Institute researchers has worked out how a new class of anti-cancer drugs kills cancer cells, a finding that helps explain how cancer cells may become resistant to treatment.

23 May 2016

Researchers genetically modify microalgae to form complex molecules

Researchers from Copenhagen Plant Science Centre at University of Copenhagen have succeeded in manipulating a strain of microalgae to form complex molecules to an unprecedented extent.

23 May 2016

Scientists take key step towards understanding link between obesity and physically distant diseases

Obesity is on the rise throughout the world, and in some developed countries two-third of the adult population is either overweight or obese. This brings with it an increased risk of serious conditions such as heart disease, stroke, cancer and osteoarthritis.

23 May 2016

Harvard researchers create new, simplified platform for antibiotic discovery

Harvard researchers have created a new, greatly simplified, platform for antibiotic discovery that may go a long way to solving the crisis of antibiotic resistance.

23 May 2016

ULK1, ULK2 enzymes play key role in maintaining cellular homeostasis

Researchers at St. Jude Children's Research Hospital have uncovered how two enzymes, ULK1 and ULK2, which are best known for their role in the degradation and recycling of proteins, control the trafficking of specific proteins.

23 May 2016

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Colorectal cancer is the second most common cause of cancer-related deaths in the Western world, mainly because it is usually diagnosed too late. Finding ways to identify those people who are at increased risk of developing colon cancer is therefore crucial, a researcher will tell the annual conference of the European Society of Human Genetics today.

23 May 2016

Inhibiting palmitate-adding enzyme can make cancer cells sensitive to EGFR inhibitors

The mistaken activation of certain cell-surface receptors contributes to a variety of human cancers. Knowing more about the activation process has led researchers to be able to induce greater vulnerability by cancer cells to an existing first-line treatment for cancers (mainly lung) driven by a receptor called EGFR.

23 May 2016

New microfluidic device helps extract rare target cells from background cells

A team of researchers from University of Cincinnati in Cincinnati, OH have developed a novel microfluidic device, which combines the inertial effect of fluid and microscale vortices generated in microchambers, to achieve simultaneous double sorting of rare target cells and removal of background cells.

23 May 2016

New, easy-to-use method for rapid testing of neutrophil chemotaxis

A team of researchers from the University of Manitoba in collaboration with local clinical scientists in Winnipeg, Canada, have developed a new method for rapid neutrophil chemotaxis test directly from a small drop of whole blood using a microfluidic system.

23 May 2016

New method helps scavenge inflammatory molecules that mediate sepsis in mice

Sepsis is a life-threatening complication of infection in which the molecules that the body releases to fight an infection trigger widespread inflammatory responses, resulting in damage to multiple organ systems.

22 May 2016

New collaborative research center to investigate promising aspects of mucosal immunology

Immunology - and the idea that many diseases can best be addressed by boosting the body's own immune response - is one of the hottest areas in medical research and clinical treatment.

22 May 2016

Nanoparticles of ultrapure silicon act as luminescent markers in early diagnosis of cancer

The group of Russian and French researchers, with the participation of scientists from the Lomonosov Moscow State University, has succeeded to synthesize nanoparticles of ultrapure silicon, which exhibited the property of efficient photoluminescence, i.e., secondary light emission after photoexcitation.

22 May 2016

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

For cancer to spread, the cells that take off into the bloodstream must find a tissue that will permit them to thrive. They don't just go looking, though. Instead, they actively prepare the tissue, in one case by co-opting a protein that suppresses defenses the body would otherwise mount.

21 May 2016

Two-way communication between cancer cells may be key to tumor metastasis

Two-way communication between cancer cells appears to be key to their becoming motile, clustering and spreading through metastasis, according to Rice University scientists.

21 May 2016

Research provides pathway toward creation of first broad-spectrum antiviral drug

By studying the rare person -- about one in a million -- who can fight off viral infections more effectively than everyone else, investigators at the Icahn School of Medicine at Mount Sinai have developed a strategy to help the rest of us achieve this enhanced anti-viral state.

21 May 2016

LIGR-Seq tool opens door to developing new understanding of ncRNA function

What used to be dismissed by many as "junk DNA" is back with a vengeance as growing data points to the importance of non-coding RNAs (ncRNAs) -- genome's messages that do not code for proteins -- in development and disease.

21 May 2016

Umea University researchers find link between vitamin E and brain tumours

Researchers at Umea University in Sweden and the Cancer Registry of Norway have studied possible causes behind the development of brain tumours.

21 May 2016

New experimental model may predict eventual cardiac phenotype in pediatric patients

An experimental model uses genetics-guided biomechanics and patient-derived stem cells to predict what type of inherited heart defect a child will develop, according to authors of a new study in the journal Cell.

21 May 2016

Specific monocyte immune cells serve as link between gut bacteria and the brain

A special kind of immune cell serves as an intermediary between gut bacteria and the brain. Dr. Susanne Wolf of the Max Delbruck Center for Molecular Medicine in the Helmholtz Association discovered this in tests on mice and published her findings in the journal Cell Reports.

20 May 2016

Malicious form of ATF2 protein drives formation of melanoma

An international collaborative study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a malicious form of a protein that drives the formation of melanoma.

20 May 2016

Medical Science News

Researchers identify potential ways in which cancer cells may develop resistance to BET inhibitors

Researchers genetically modify microalgae to form complex molecules

Scientists take key step towards understanding link between obesity and physically distant diseases

Harvard researchers create new, simplified platform for antibiotic discovery

ULK1, ULK2 enzymes play key role in maintaining cellular homeostasis

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Inhibiting palmitate-adding enzyme can make cancer cells sensitive to EGFR inhibitors

New microfluidic device helps extract rare target cells from background cells

New, easy-to-use method for rapid testing of neutrophil chemotaxis

New method helps scavenge inflammatory molecules that mediate sepsis in mice

New collaborative research center to investigate promising aspects of mucosal immunology

Nanoparticles of ultrapure silicon act as luminescent markers in early diagnosis of cancer

Wresting back control of CHI3L1 protein could stave off cancer spread in mice

Two-way communication between cancer cells may be key to tumor metastasis

Research provides pathway toward creation of first broad-spectrum antiviral drug

LIGR-Seq tool opens door to developing new understanding of ncRNA function

Umea University researchers find link between vitamin E and brain tumours

New experimental model may predict eventual cardiac phenotype in pediatric patients

Specific monocyte immune cells serve as link between gut bacteria and the brain

Malicious form of ATF2 protein drives formation of melanoma

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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