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Researchers explain interaction between HNRNPA2B1 protein and pancreatic cancer development

Researchers from the University of Barcelona have described an interaction between the protein HNRNPA2B1 and pancreatic cancer development which remained unknown. The study, published in the journal Gastroenterology, has proved in human cancer cell lines that this protein is essential to the correct activity of the oncogenic protein KRAS, related to cancer start and development.

11 Nov 2014

Olympus to host fifth annual neuroimaging symposium in conjunction with 2014 annual meeting of the Society for Neuroscience

Olympus is hosting its fifth annual neuroimaging symposium in conjunction with the 2014 annual meeting of the Society for Neuroscience (SfN) on Monday, November 17 at 6:30pm in Washington DC. The Olympus Neuroimaging Symposium and reception will be held at the Marriott Marquis Washington, DC, 901 Massachusetts Avenue NW, in the Capitol and Congress ballrooms. It is open to all media and registered SfN attendees.

From Evident Corporation - Life Sciences 10 Nov 2014

LSTM receives research grants to develop Experimental Human Pneumococcal Carriage model

Respiratory specialists at Liverpool School Tropical Medicine (LSTM) have been awarded two substantial research grants to further develop and utilise their Experimental Human Pneumococcal Carriage (EHPC) model.

10 Nov 2014

UF Health researcher finds way to grow human norovirus

Noroviruses are pernicious intestinal viruses. They cause violent vomiting and diarrhea, and people ill with the virus remain contagious up to three days after they seem to recover.

9 Nov 2014

Worst effects of reperfusion injury after heart attack may be prevented with iodide

Blocked arteries are typically the trigger, stopping the flow of blood and starving the heart muscle of oxygen. But when the blockage is removed and the blood comes rushing back, it wreaks havoc of its own. The result is called reperfusion injury, a life-threatening flood of inflammation and cellular destruction that has stumped scientists for 40 years.

9 Nov 2014

Researchers find way to defeat elusive target proteins in cancer cells

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found a way to defeat one of the most tantalizing yet elusive target proteins in cancer cells - employing a strategy that turns the protein's own molecular machinations against it.

9 Nov 2014

New vaccination approach can reduce tumor burden, suppress formation of lung metastases

In a new study published in the scientific journal Oncotarget researchers from Uppsala University show that a therapeutic vaccine directed against tumor vessels can reduce tumor burden and suppress formation of spontaneous lung metastases in a mouse model for metastatic breast cancer.

9 Nov 2014

Scientists may have discovered new way to repair damaged tissue

By transforming human scar cells into blood vessel cells, scientists at Houston Methodist may have discovered a new way to repair damaged tissue. The method, described in an upcoming issue of Circulation (early online), appeared to improve blood flow, oxygenation, and nutrition to areas in need.

9 Nov 2014

UCSD researchers describe surprising role of protein in embryonic development

Hematopoietic stem cells (HSCs) give rise to all blood and immune cells throughout the life of vertebrate organisms, from zebrafish to humans. But details of their genesis remain elusive, hindering efforts to develop induced pluripotent stem cell (iPSC) replacements that might address a host of blood disorders.

7 Nov 2014

Induced neural stem cells hold promise for therapeutic transplantation

Induced neural stem cells (iNSCs) created from adult cells hold promise for therapeutic transplantation, but their potential in this capacity has been limited by failed efforts to maintain such cells in the desirable multi-potent NSC state without continuous expression of the transcription factors used initially to reprogram them.

7 Nov 2014

Findings pave way for personalized probiotic therapies for obesity-related diseases

Our genetic makeup influences whether we are fat or thin by shaping which types of microbes thrive in our body, according to a Cornell-led study published today in the journal Cell.

7 Nov 2014

Researchers discover new genetic cause of rare, complex form of epilepsy

A research team led by scientists at the Scripps Translational Science Institute has used whole genome sequencing to identify a new genetic cause of a severe, rare and complex form of epilepsy that becomes evident in early childhood and can lead to early death.

7 Nov 2014

Liposomes can help prevent bacterial toxins from killing human cells

Published in Nature Biotechnology, the study at the University of Liverpool showed that specially engineered lipid (fat) bodies, called liposomes, can be used to prevent bacterial toxins from killing human cells.

7 Nov 2014

Regenerative medicine may offer new standard of advanced treatment for foot and leg ulcers

These are exciting times for regenerative medicine. Unlike conventional medicines, the regenerative approach can potentially work to restore the lost functionality of tissues or organs—the major reason for intensive focus on research and development in the field.

7 Nov 2014

Researchers obtain detailed picture of how Gas5 RNA interacts with steroid hormone receptors

It arises from what scientists previously described as "junk DNA" or "the dark matter of the genome," but this gene is definitely not junk.

7 Nov 2014

Single mutation in beta-catenin gene can lead to infertility

Scientists from the RIKEN BioResource Center in Tsukuba, Japan, have discovered that a single mutation in the beta-catenin gene, which codes a protein known to be deeply involved in a number of developmental and homeostatic processes, can lead to infertility not through a disruption of the production of egg or sperm cells, but rather by leading to abnormalities in the morphology of the sexual organs, making natural reproduction impossible.

7 Nov 2014

Researchers synthetize molecules to block virus that causes influenza A

The influenza A virus is a contagious and severe respiratory infection that affects animals but also humans. Researchers from the University of Barcelona have synthetized some molecules which are able to block the virus that causes influenza A and some of the mutations that make it resistant to common drugs.

7 Nov 2014

Zinc supplements more beneficial for some people with diabetes

Researchers at the Johns Hopkins University School of Medicine and elsewhere have found that genetic differences may account for why zinc supplements are more beneficial to some people than to others for the prevention and control of diabetes. The results of their pilot study of a population of Old Order Amish is believed to be the first to point out the relevance of small genetic differences in response to zinc supplementation at play in diabetes management.

7 Nov 2014

McLean Hospital lab explores use of stem cell therapy to treat epilepsy

McLean Hospital and Harvard Stem Cell Institute scientists have new evidence that stem cell transplantation could be a worthwhile strategy to help epileptics who do not respond to anti-seizure drugs.

7 Nov 2014

Genetically diverse mouse model can predict human response to chemical exposures

A genetically diverse mouse model is able to predict the range of response to chemical exposures that might be observed in human populations, researchers from the National Institutes of Health have found. Like humans, each Diversity Outbred mouse is genetically unique, and the extent of genetic variability among these mice is similar to the genetic variation seen among humans.

7 Nov 2014

Medical Science News

Researchers explain interaction between HNRNPA2B1 protein and pancreatic cancer development

Olympus to host fifth annual neuroimaging symposium in conjunction with 2014 annual meeting of the Society for Neuroscience

LSTM receives research grants to develop Experimental Human Pneumococcal Carriage model

UF Health researcher finds way to grow human norovirus

Worst effects of reperfusion injury after heart attack may be prevented with iodide

Researchers find way to defeat elusive target proteins in cancer cells

New vaccination approach can reduce tumor burden, suppress formation of lung metastases

Scientists may have discovered new way to repair damaged tissue

UCSD researchers describe surprising role of protein in embryonic development

Induced neural stem cells hold promise for therapeutic transplantation

Findings pave way for personalized probiotic therapies for obesity-related diseases

Researchers discover new genetic cause of rare, complex form of epilepsy

Liposomes can help prevent bacterial toxins from killing human cells

Regenerative medicine may offer new standard of advanced treatment for foot and leg ulcers

Researchers obtain detailed picture of how Gas5 RNA interacts with steroid hormone receptors

Single mutation in beta-catenin gene can lead to infertility

Researchers synthetize molecules to block virus that causes influenza A

Zinc supplements more beneficial for some people with diabetes

McLean Hospital lab explores use of stem cell therapy to treat epilepsy

Genetically diverse mouse model can predict human response to chemical exposures

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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