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MGH-CEM researchers develop microfabricated device to analyze effects of pro-drugs on cancer cells

A team of researchers from the Massachusetts General Hospital Center for Engineering in Medicine has developed a novel approach that dramatically simplifies the evaluation of the liver's drug-metabolizing activity and the potential toxic effects of the products of that activity on other organs.

8 Jul 2015

IRB Barcelona scientists provide molecular details about Seckel Syndrome

Today in Nature Communications, scientists at the Institute for Research in Biomedicine (IRB Barcelona) provide molecular details about Seckel Syndrome, a rare disease that causes microcephaly, or small brain, and growth delays.

8 Jul 2015

UC Davis scientists identify significant driver of neuropathic pain

Scientists at the University of California, Davis, have identified a key mechanism in neuropathic pain. The discovery could eventually benefit millions of patients with chronic pain from trauma, diabetes, shingles, multiple sclerosis or other conditions that cause nerve damage.

8 Jul 2015

Georgia State University-led study identifies structural brain abnormalities in schizophrenia patients

Structural brain abnormalities in patients with schizophrenia, providing insight into how the condition may develop and respond to treatment, have been identified in an internationally collaborative study led by a Georgia State University scientist.

7 Jul 2015

Changes in key biomarkers of Alzheimer’s disease during midlife may help predict future dementia risk

Studying brain scans and cerebrospinal fluid of healthy adults, scientists have shown that changes in key biomarkers of Alzheimer's disease during midlife may help identify those who will develop dementia years later, according to new research.

7 Jul 2015

Tests reveal that FY26 cancer drug is 49 times more potent than Cisplatin drug

Tests have shown that a new cancer drug, FY26, is 49 times more potent than the clinically used treatment Cisplatin.

7 Jul 2015

Study sheds light on how dengue virus adapts, causes outbreaks as it travels

A researcher from The University of Texas Medical Branch at Galveston is an integral member of a collaborative group that is the first to explain the mechanisms that the Dengue virus has developed to optimize its ability to cause outbreaks as it travels across the globe to new places and revisits old ones.

7 Jul 2015

Commercially available headphones unlikely to interfere with programmable shunt valve settings

Researchers at Brown University examined three magnetically programmable shunt valves to see if the magnetic field emissions of headphones can cause unintentional changes in shunt valve settings. Based on their findings, the researchers state that it is highly unlikely that commercially available headphones will interfere with programmable shunt valve settings.

7 Jul 2015

Mild head injury patients having lower serum S100B levels unlikely to have intracranial hemorrhage

Researchers conducted a prospective observational study in elderly patients and adult patients receiving antiplatelet therapy who presented with mild head injury at two trauma hospitals in Vienna: the Trauma Hospital Meidling and the Donauspital.

7 Jul 2015

Discovery could pave way to new treatments for malaria

Scientists have discovered new ways in which the malaria parasite survives in the blood stream of its victims, a discovery that could pave the way to new treatments for the disease.

7 Jul 2015

New research shows that risk of cardiovascular disease and early death falls due to vitamin C

New research from the University of Copenhagen and Herlev and Gentofte Hospital shows that high vitamin C concentrations in the blood from the intake of fruit and vegetables are associated with a reduced risk of cardiovascular disease and early death.

7 Jul 2015

City of Hope researchers to use patients' own modified T cells to treat advanced brain tumors

Already pioneers in the use of immunotherapy, City of Hope researchers are now testing the bold approach to cancer treatment against one of medicine's biggest challenges: brain cancer. This month, they will launch a clinical trial using patients' own modified T cells to fight advanced brain tumors.

7 Jul 2015

Researchers pinpoint two biomarkers elevated in severe form of coronary disease

Insulin resistance affects tens of millions of Americans and is a big risk factor for heart disease. Yet, some people with the condition never develop heart disease, while some experience moderate coronary blockages. Others, though, get severe atherosclerosis - multiple blockages and deterioration of coronary arteries characterized by thick, hard, plaque-ridden arterial walls.

7 Jul 2015

LSD1 enzyme turns off genes needed to maintain cancer stem cell properties in glioblastoma

Cancer's ability to grow unchecked is often attributed to cancer stem cells, a small fraction of cancer cells that have the capacity to grow and multiply indefinitely. How cancer stem cells retain this property while the bulk of a tumor's cells do not remains largely unknown. Using human tumor samples and mouse models, researchers at University of California, San Diego School of Medicine and Moores Cancer Center discovered that cancer stem cell properties are determined by epigenetic changes -- chemical modifications cells use to control which genes are turned on or off.

7 Jul 2015

Dental pulp stem cell transplants can contribute to peripheral nerve regeneration

Peripheral nerve injuries often are caused by trauma or surgical complications and can result in considerable disabilities. Regeneration of peripheral nerves can be accomplished effectively using autologous (self-donated) nerve grafts, but that procedure may sacrifice a functional nerve and cause loss of sensation in another part of the patient's body.

7 Jul 2015

Bacterial biofilms play role in development of systemic lupus erythematosus

Lupus, multiple sclerosis, and type-1 diabetes are among more than a score of diseases in which the immune system attacks the body it was designed to defend. But just why the immune system begins its misdirected assault has remained a mystery.

7 Jul 2015

WPI-led study provides clues to new ways to treat difficult-to-cure fungal infections

A study by a multidisciplinary research team, co-directed by Worcester Polytechnic Institute, offers new insights into how virulent fungi adapt through genetic modifications to fight back against the effects of medication designed to block their spread, and how that battle leaves them temporarily weakened. These insights may provide clues to new ways to treat notoriously difficult-to-cure fungal infections like thrush and vaginitis.

7 Jul 2015

Findings reveal new pathway to develop effective treatments and therapies for asthma, allergy

Investigators have discovered the precise molecular steps that enable immune cells implicated in certain forms of asthma and allergy to develop and survive in the body. The findings from Weill Cornell Medical College reveal a new pathway that scientists could use to develop more effective treatments and therapies for the chronic lung disorder.

7 Jul 2015

Researchers identify link between autoimmune diseases, medications and Long QT syndrome

Mohamed Boutjdir, PhD, professor of medicine, cell biology, and physiology and pharmacology at SUNY Downstate Medical Center, has led a study with international collaborators identifying the mechanism by which patients with various autoimmune and connective tissue disorders may be at risk for life-threatening cardiac events if they take certain anti-histamine or anti-depressant medications.

7 Jul 2015

Penn biologists reveal recent migratory history of blacklegged ticks in Northeastern United States

Lyme disease cases are on the rise, with diagnoses occurring in areas that were historically Lyme-free. Scientists attribute the spread to the fact that populations of blacklegged ticks, which carry the bacteria that causes the disease, now flourish in areas once thought to be devoid of ticks.

7 Jul 2015

Medical Science News

MGH-CEM researchers develop microfabricated device to analyze effects of pro-drugs on cancer cells

IRB Barcelona scientists provide molecular details about Seckel Syndrome

UC Davis scientists identify significant driver of neuropathic pain

Georgia State University-led study identifies structural brain abnormalities in schizophrenia patients

Changes in key biomarkers of Alzheimer’s disease during midlife may help predict future dementia risk

Tests reveal that FY26 cancer drug is 49 times more potent than Cisplatin drug

Study sheds light on how dengue virus adapts, causes outbreaks as it travels

Commercially available headphones unlikely to interfere with programmable shunt valve settings

Mild head injury patients having lower serum S100B levels unlikely to have intracranial hemorrhage

Discovery could pave way to new treatments for malaria

New research shows that risk of cardiovascular disease and early death falls due to vitamin C

City of Hope researchers to use patients' own modified T cells to treat advanced brain tumors

Researchers pinpoint two biomarkers elevated in severe form of coronary disease

LSD1 enzyme turns off genes needed to maintain cancer stem cell properties in glioblastoma

Dental pulp stem cell transplants can contribute to peripheral nerve regeneration

Bacterial biofilms play role in development of systemic lupus erythematosus

WPI-led study provides clues to new ways to treat difficult-to-cure fungal infections

Findings reveal new pathway to develop effective treatments and therapies for asthma, allergy

Researchers identify link between autoimmune diseases, medications and Long QT syndrome

Penn biologists reveal recent migratory history of blacklegged ticks in Northeastern United States

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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