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MGH researchers develop bioartificial replacement limbs suitable for transplantation

A team of Massachusetts General Hospital investigators has made the first steps towards development of bioartificial replacement limbs suitable for transplantation. In their report, which has been published online in the journal Biomaterials, the researchers describe using an experimental approach previously used to build bioartificial organs to engineer rat forelimbs with functioning vascular and muscle tissue.

3 Jun 2015

Scientists identify novel mechanism that can reorganize cell's genetic architecture to promote senescence

Senescence, a phenomenon in which cells cease to divide and grow, can be caused by everything from natural DNA damage to treatment with chemotherapy. However, several mechanisms allow for cells to bypass senescence and grow out of control, eventually becoming cancerous.

3 Jun 2015

Research finding could explain why HIV envelope protein has a long tail

Virologists at Emory University School of Medicine, Yerkes National Primate Research Center, and Children's Healthcare of Atlanta have uncovered a critical detail explaining how HIV assembles its infectious yet stealthy clothing.

3 Jun 2015

UC Santa Cruz-led study offers new insights into molecular mechanisms of biological clock

A new study led by UC Santa Cruz researchers has found that a protein associated with cancer cells is a powerful suppressor of the biological clock that drives the daily ("circadian") rhythms of cells throughout the body.

3 Jun 2015

BioCision, CCT to develop ThawSTAR automated cell thawing system for treatment of diabetic foot ulcers

BioCision, LLC, a leader in advanced technology to improve biological sample handling and standardization, today announced that it will collaborate with Celgene Cellular Therapeutics (CCT) (a subsidiary of Celgene Corporation), to accelerate the development of a cell thawing solution based on BioCision’s proprietary ThawSTARÔ technology for the 6 mL injectable vial that CCT has chosen to store PDA-002, a cryopreserved, allogeneic cell therapy currently in clinical development to treat diabetic foot ulcers in patients with peripheral arterial disease.

3 Jun 2015

Researchers transform bacteria into 'secret agents' for detecting disease

Another step forward has just been taken in the area of synthetic biology. Research teams from Inserm and CNRS (French National Centre for Scientific Research) Montpellier, in association with Montpellier Regional University Hospital and Stanford University, have transformed bacteria into "secret agents" that can give warning of a disease based solely on the presence of characteristic molecules in the urine or blood. To perform this feat, the researchers inserted the equivalent of a computer programme into the DNA of the bacterial cells.

3 Jun 2015

University of Bonn researchers find way to stimulate larynx muscles using light

Researchers at the University of Bonn have found a way to stimulate the larynx muscles of mice using light. In the long term, this method could be an option for the treatment of laryngeal paralysis, which causes difficulties in phonation and breathing. Their findings will be published in the scientific journal "Nature Communications."

3 Jun 2015

Northeastern University researcher reports finding epicenter of brain's prediction

In recent years, scientists have discovered the human brain works on predictions, contrary to the previously accepted theory that it reacts to the sensations it picks up from the outside world. Experts say humans' reactions are in fact the body adjusting to predictions the brain is making based on the state of our body the last time it was in a similar situation.

3 Jun 2015

ProBioGen initiates clinical trials of Ebola vaccine using AGE1.CR.pIX cell line

Complex biologics development and manufacturing specialist ProBioGen today announced that an investigational vaccine against Ebola virus disease, produced on its proprietary, continuous muscovy duck AGE1.CR.pIX cell line, has proceeded into clinical trials at the Jenner Institute, Oxford University, UK.

3 Jun 2015

Ovizio unveils new in-line suspension cell-monitoring microscope at ESACT

Ovizio Imaging System, an innovative quantitative microscopy company specializing in life science solutions, announces today the launch of its new product, the iLine F, an in-line suspension cell-monitoring microscope.

3 Jun 2015

Scientists identify gene mutation that causes color blindness

A rare eye disorder marked by color blindness, light sensitivity, and other vision problems can result from a newly discovered gene mutation identified by an international research team, including scientists from Columbia University Medical Center.

3 Jun 2015

New study sheds light on the disruption of astrocytes in depression

A new study published by the team of Naguib Mechawar, Ph.D., a researcher with the McGill Group for Suicide Studies of the Douglas Institute (CIUSSS de l'Ouest-de-l'Ile de Montreal) and associate professor in the Department of Psychiatry at McGill University, sheds new light on the disruption of astrocytes in depression.

3 Jun 2015

New finding may lead to development of immunity-based therapies for tuberculosis

A study by researchers at UT Southwestern Medical Center has identified how an enzyme involved in protecting the body from pathogens senses Mycobacterium tuberculosis (TB), a bacterial pathogen that infects millions of people worldwide and causes about 1.5 million deaths annually.

2 Jun 2015

Leica Microsystems to acquire OCT company Bioptigen

Bioptigen develops and manufactures innovative OCT systems and software and is globally successful with products for clinical as well as translational research applications. Using low-power, near-infrared light, Bioptigen OCTs generate high-resolution, volumetric images of the eye...

From Leica Microsystems GmbH 2 Jun 2015

MedImmune, AstraZeneca present encouraging results from new combination-focused immuno-oncology portfolio at ASCO 2015

AstraZeneca and MedImmune, the company’s global biologics research and development arm, today presented encouraging results from their novel combination-focused immuno-oncology portfolio at the American Society of Clinical Oncology (ASCO) Annual Meeting 2015.

2 Jun 2015

Ariana Pharma joins the GastricGlycoExplorer consortium

This collaboration is carried out within the GastricGlycoExplorer consortium, a European Commission funded project. The consortium aims at discovering and developing new diagnostic signatures by characterizing the sugars that are attached to the surface of gastric tissue. "Glycomics" provides a systematic approach for studying sugars that are naturally present on cell surfaces and its application may lead to determine early markers of gastric cancer.

2 Jun 2015

$Matched therapy and FoundationOne genomic profiling improve outcomes in patients with refractory cancer$

Matched therapy and FoundationOne genomic profiling improve outcomes in patients with refractory cancer

Foundation Medicine, Inc. and collaborators from the University of Texas MD Anderson Cancer Center and Sarah Cannon Research Institute at HealthOne today announced compelling new data demonstrating that matching patients to targeted therapies based on the unique molecular profile of the patient’s advanced cancer leads to improved outcomes across a variety of key measures, including overall survival.

2 Jun 2015

New data underscores the importance of FoundationOne genomic profiling for treatment of biliary tract cancers

Foundation Medicine, Inc. today presented new data including promising clinical outcomes underscoring the importance of integrating comprehensive genomic profiling with FoundationOne® into clinical oncology care for the treatment of biliary tract cancers.

2 Jun 2015

Two new groups of viruses discovered within Bunyavirus family in Ivory Coast tropical forest

Researchers at the University of Bonn and the German Center for Infection Research (DZIF) have discovered two new groups of viruses within the Bunyavirus family in the tropical forest of Ivory Coast. Previously only five groups responsible for serious illnesses in humans and animals were known.

2 Jun 2015

Northeastern University researchers report two approaches to eradicate Lyme disease

Northeastern University researchers have found that the bacterium that causes Lyme disease forms dormant persister cells, which are known to evade antibiotics. This significant finding, they said, could help explain why it's so difficult to treat the infection in some patients.

2 Jun 2015

Medical Science News

MGH researchers develop bioartificial replacement limbs suitable for transplantation

Scientists identify novel mechanism that can reorganize cell's genetic architecture to promote senescence

Research finding could explain why HIV envelope protein has a long tail

UC Santa Cruz-led study offers new insights into molecular mechanisms of biological clock

BioCision, CCT to develop ThawSTAR automated cell thawing system for treatment of diabetic foot ulcers

Researchers transform bacteria into 'secret agents' for detecting disease

University of Bonn researchers find way to stimulate larynx muscles using light

Northeastern University researcher reports finding epicenter of brain's prediction

ProBioGen initiates clinical trials of Ebola vaccine using AGE1.CR.pIX cell line

Ovizio unveils new in-line suspension cell-monitoring microscope at ESACT

Scientists identify gene mutation that causes color blindness

New study sheds light on the disruption of astrocytes in depression

New finding may lead to development of immunity-based therapies for tuberculosis

Leica Microsystems to acquire OCT company Bioptigen

MedImmune, AstraZeneca present encouraging results from new combination-focused immuno-oncology portfolio at ASCO 2015

Ariana Pharma joins the GastricGlycoExplorer consortium

Matched therapy and FoundationOne genomic profiling improve outcomes in patients with refractory cancer

New data underscores the importance of FoundationOne genomic profiling for treatment of biliary tract cancers

Two new groups of viruses discovered within Bunyavirus family in Ivory Coast tropical forest

Northeastern University researchers report two approaches to eradicate Lyme disease

In the Thymus We Trust: ProTcell Therapy & the Future of Allogeneic Immunotherapy

Making Complex Cell Culture Easy and Efficient with AI

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

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