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Manipulation of signals in nervous system can enhance recovery after traumatic injury

Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. They also found that manipulating these signals can enhance the return of function.

12 Apr 2016

Bacteroidia pilins prevalent in human gut and mouth form new type of pili to cling to hosts

Many bacteria interact with their environment through hair-like structures known as pili, which attach to and help mediate infection of host organisms, among other things. Now a U.S.-Japanese research team, including scientists from the Department of Energy's SLAC National Accelerator Laboratory, has discovered that certain bacteria prevalent in the human gut and mouth assemble their pili in a previously unknown way - information that could potentially open up new ways of fighting infection.

12 Apr 2016

Six newly identified proteins may help potentially unlock new insights into aging-related diseases

A group of six newly discovered proteins may help to divulge secrets of how we age, potentially unlocking new insights into diabetes, Alzheimer's, cancer, and other aging-related diseases.

12 Apr 2016

Distribution of c-Myc protein during asymmetric cell division influences fate, roles of activated T cells

The fates of immune cells can be decided at the initial division of a cell. Researchers at St. Jude Children's Research Hospital have discovered that the production of daughter cells with different roles in the immune system is driven by the lopsided distribution of the signaling protein c-Myc. Nudging c-Myc in one direction or the other could make vaccines more effective or advance immunotherapies for cancer treatment. The research appears online today in the scientific journal Nature.

12 Apr 2016

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

A signaling molecule called interferon gamma could hold the key to understanding how harmful autoantibodies form in lupus patients. The finding could lead to new treatments for the chronic autoimmune disease, said researchers at Penn State College of Medicine.

12 Apr 2016

Alternative splicing regulates MALT1 protein to have stronger or weaker effect on immune system

The protein MALT1 is an important switch in immune cells and affects their activity. Researchers at Helmholtz Zentrum München report in 'Nature Communications' that this activation is not always equally strong. Through alternative splicing, two variants of the protein may arise which have a stronger or weaker effect on the immune system. Understanding this process is important for the pharmacological use of MALT1.

12 Apr 2016

New biomarker discovery could improve chances of developing effective TB vaccine

A team of scientists led by Oxford University have made a discovery that could improve our chances of developing an effective vaccine against Tuberculosis.

12 Apr 2016

New European standard method can help measure inorganic arsenic content in foods

A new European standard method to determine the content of inorganic arsenic in foodstuffs has been developed at the National Food Institute, Technical University of Denmark. Inorganic arsenic is carcinogenic according to the World Health Organization, WHO. Being able to accurately measure the substance in different foods is necessary to ensure that the content is below the maximum levels recently set by the European Commission to protect consumers.

12 Apr 2016

Bonn mathematicians develop new model for cancer immunotherapy

Mathematicians and physicians at the University of Bonn have developed a new model for immunotherapy of cancer. The method could help to develop new treatment strategies and to understand why some approaches do not work with certain tumors. The study is now appearing in the technical journal "Scientific Reports".

12 Apr 2016

$New sensitive detection method could help measure subfractions of HDL$

New sensitive detection method could help measure subfractions of HDL

High-density lipoprotein (HDL) is often referred to as good cholesterol: high levels of HDL are associated with lower risk of cardiovascular disease. But many clinical outcome trials for drugs that raise HDL levels have failed to show significant benefits for trial participants.

12 Apr 2016

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Writing in the April 11 issue of The Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer's disease (AD) and Down syndrome (DS).

12 Apr 2016

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

In a new study, a research team at Basel University Hospital in Switzerland investigates the biochemical and physiological characteristics of orbicularis oculi, a group of facial muscles that control the eyelids and are selectively spared or involved in different neuromuscular disorders. What they found also helps to explain why another set of muscles—the extraocular muscles that control the movement of the eye—are not affected by Duchenne muscular dystrophy, congenital muscular dystrophy, and aging.

12 Apr 2016

Leica Microsystems launches new camera for imaging live cells under near-native conditions

Leica Microsystems launches the Leica DFC9000, a monochrome microscope camera with a highly sensitive third-generation sCMOS sensor. The camera enables researchers to image live cells under near-native conditions, allowing them to gain a better understanding of cellular processes and dynamics.

From Leica Microsystems GmbH 12 Apr 2016

Researchers develop new technology to tailor grafted tissues

Researchers from the Technion-Israel Institute of Technology and colleagues in the U.S. have developed technology to tailor grafted tissues that can respond to certain natural forces affecting blood vessels.

12 Apr 2016

Brazilian researchers reveal harmful effects of Zika virus in human neural stem cells, neurospheres

Brazilian researchers from the D'Or Institute for Research and Education (IDOR) and Federal University of Rio de Janeiro (UFRJ) have demonstrated the harmful effects of ZIKA virus (ZIKV) in human neural stem cells, neurospheres and brain organoids.

12 Apr 2016

Certain red blood cell manufacturing methods may be less damaging to cells than others

Scientists from Blood Systems Research Institute in San Francisco, California, and Canadian Blood Services' Centre for Innovation lab in Edmonton, Alberta, report for the first time that specific red blood cell manufacturing methods may be less damaging to cells than others.

12 Apr 2016

Porvair Sciences to launch new microplate for genomics at Analytica 2016

Porvair Sciences has announced that it will launch an exciting new microplate for genomics sample preparation at the forthcoming Analytica 2016 exhibition in Munich, Germany.

From Porvair Sciences Limited 12 Apr 2016

New plant-derived oral drug can prevent progression of multiple sclerosis

An international research team has demonstrated that a new plant-derived drug can block the progression of multiple sclerosis (MS).

12 Apr 2016

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

In a new study, researchers from Columbia University Medical Center described a new mouse model featuring a combination of genetic and environmental risk factors that can trigger the compulsive restriction of food intake seen in patients with anorexia nervosa. The findings may help to identify new prevention and treatment strategies for the eating disorder in humans.

12 Apr 2016

Increased expression of VEGF-A promotes three common aging-related eye conditions

A Massachusetts General Hospital investigator has found that increased expression of the angiogenic factor VEGF-A promotes three common aging-related eye conditions - both versions of age-related macular degeneration (AMD) and also cataracts - in an animal model.

12 Apr 2016

Medical Science News

Manipulation of signals in nervous system can enhance recovery after traumatic injury

Bacteroidia pilins prevalent in human gut and mouth form new type of pili to cling to hosts

Six newly identified proteins may help potentially unlock new insights into aging-related diseases

Distribution of c-Myc protein during asymmetric cell division influences fate, roles of activated T cells

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

Alternative splicing regulates MALT1 protein to have stronger or weaker effect on immune system

New biomarker discovery could improve chances of developing effective TB vaccine

New European standard method can help measure inorganic arsenic content in foods

Bonn mathematicians develop new model for cancer immunotherapy

New sensitive detection method could help measure subfractions of HDL

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Researchers investigate biochemical, physiological characteristics of facial and extraocular muscles

Leica Microsystems launches new camera for imaging live cells under near-native conditions

Researchers develop new technology to tailor grafted tissues

Brazilian researchers reveal harmful effects of Zika virus in human neural stem cells, neurospheres

Certain red blood cell manufacturing methods may be less damaging to cells than others

Porvair Sciences to launch new microplate for genomics at Analytica 2016

New plant-derived oral drug can prevent progression of multiple sclerosis

Combination of genetic, environmental risk factors can trigger fatal eating disorder in humans

Increased expression of VEGF-A promotes three common aging-related eye conditions

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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